Traditional Chinese medicine plastic for treating phase-I and phase-II pressure sores and preparation method of traditional Chinese medicine plastic

A film coating agent and a traditional Chinese medicine technology, which are applied to the traditional Chinese medicine film coating agent for stage II pressure ulcers and its preparation, and the field of treatment I can solve the problems of affecting the healing time of the wound, great pain for the patient, and low effective ingredients, and achieve the improvement of the microscopic wound surface. Circulatory disturbance and persistent pain, dredging of meridians, high effect of active active ingredients

Inactive Publication Date: 2015-12-23
QINGDAO YUNTIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Surgical treatment is risky, with large openings, great pain for patients, high cost, and slow healing; the use of antibiotics is only effective for wound infection, but it affects the healing time of wounds and prolongs the pain of patients
However, the existing traditional Chinese medicines for the treatment of decubitus are mostly outdated dosage forms such as powders or ointments, and there are widespread problems of complex drug compatibility, extensive preparation technology, and unreasonable selection of substrates, resulting in low active ingredients, excessive dosage, and incomplete efficacy. Play and other shortcomings

Method used

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  • Traditional Chinese medicine plastic for treating phase-I and phase-II pressure sores and preparation method of traditional Chinese medicine plastic
  • Traditional Chinese medicine plastic for treating phase-I and phase-II pressure sores and preparation method of traditional Chinese medicine plastic
  • Traditional Chinese medicine plastic for treating phase-I and phase-II pressure sores and preparation method of traditional Chinese medicine plastic

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0087] Prescription for clear ointment: 20 servings of three needles, 12 servings of ten major meritorious service leaves, 15 servings of bark vine, 8 servings of liangmianzhen, 17 servings of Hibiscus leaves, and 9 servings of Angelica dahurica;

[0088] Prescription of coating agent (by weight percentage): 12% of traditional Chinese medicine clear ointment, 24881.3% of polyvinyl alcohol, 1.9% of water-soluble chitosan, 6% of glycerin, Tween-800.8%, 1.0% of borneol, 77.0% of water;

[0089] The preparation method of the coating agent: take the medicinal material of Liangmianzhen, percolate with water, collect the percolation liquid, pass the percolation liquid through the macroporous adsorption resin, first elute with water to remove impurities soluble in polar solvents, and use the water eluate Discard it and use it for elution with 80% high-concentration ethanol to collect the eluate of Liangmianzhen ethanol;

[0090] Grind the three needles, Shigonggong leaves, Angelica da...

Embodiment 2

[0093] Prescription for clear ointment: 20 servings of three needles, 12 servings of ten major meritorious service leaves, 15 servings of bark vine, 8 servings of liangmianzhen, 17 servings of Hibiscus leaves, and 9 servings of Angelica dahurica;

[0094] Prescription of coating agent (by weight percentage): 15% of traditional Chinese medicine clear ointment, 24881.7% of polyvinyl alcohol, 2.6% of water-soluble chitosan, 8% of glycerin, Tween-801.0%, 1.0% of borneol, 70.7% of water;

[0095] The preparation method of the coating agent: take the medicinal material of Liangmianzhen, percolate with water, collect the percolation liquid, pass the percolation liquid through the macroporous adsorption resin, first elute with water to remove impurities soluble in polar solvents, and use the water eluate Discard it and use it for elution with 80% high-concentration ethanol to collect the eluate of Liangmianzhen ethanol;

[0096] Grind the three needles, Shigonggong leaves, Angelica da...

Embodiment 3

[0099] Prescription for clear ointment: 25 servings of Three Needles, 15 servings of Shiba Gongluo Leaf, 16 servings of Barbadensis, 10 servings of Liangmianzhen, 15 servings of Hibiscus Leaf, and 10 servings of Angelica dahurica;

[0100] Prescription of coating agent (by weight percentage): 10% of traditional Chinese medicine clear ointment, 24881.5% of polyvinyl alcohol, 2.7% of water-soluble chitosan, 7.3% of glycerin, Tween-800.9%, 1.1% of borneol, 76.5% of water;

[0101] The preparation method of the coating agent: take the medicinal material of Liangmianzhen, percolate with water, collect the percolation liquid, pass the percolation liquid through the macroporous adsorption resin, first elute with water to remove impurities soluble in polar solvents, and use the water eluate Discard it and use it for elution with 80% high-concentration ethanol to collect the eluate of Liangmianzhen ethanol;

[0102] Grind the three needles, Shigonggong leaves, Angelica dahurica, Cinnam...

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PUM

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Abstract

The invention particularly relates to traditional Chinese medicine plastic for treating phase-I and phase-II pressure sores and a preparation method of the traditional Chinese medicine plastic and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine plastic is prepared from 1%-30% of traditional Chinese medicine sugarless paste, 0.5%-5% of polyvinyl alcohol 2488, 0.5%-10% of water-soluble chitosan, 3%-10% of glycerinum, 0.5%-1.5% of polysorbate-80, 0.5%-1.5% of borneol and water. The traditional Chinese medicine clear paste is prepared from roots of Chinese barberry, Chinese mahonia leaves, Root or stem of Creeping Mallotus, radix zanthoxyli, cottonrose hibiscus leaves and radix angelicae. The plastic has the effects of promoting blood circulation to remove blood stasis, clearing away heat and toxic materials, relieving swelling and pain, resisting bacteria, diminishing inflammation and improving wound surface microcirculation disturbance and durable pain, skin channels can be dredged, toxin and necrotic tissue are removed, bruises are eliminated, and new flesh is generated by itself. The effect on the phase-I and phase-II pressure sores is remarkable, specificity is high, use is convenient, and high clinical popularization value is achieved.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine film-coating agent for treating stage I and stage II pressure sores and a preparation method thereof. Background technique [0002] Pressure sores are also called decubitus ulcers or pressure ulcers. Due to the long-term pressure on the local tissues, the blood circulation is disturbed, and the tissues continue to be in a state of ischemia, hypoxia, and malnutrition, so that the skin gradually loses its normal physiological functions. tissue damage and necrosis. Traditional Chinese medicine calls pressure sores "bed sores". According to TCM theory, pressure sores are caused by long-term bed mats due to serious illnesses. The patient is under pressure for a long time and cannot turn to the side. The tendons and veins have been lost for a long time and cultivated by Confucianism. [0003] The current clinically generally acce...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/758A61K9/70A61P17/02
Inventor 王传秀
Owner QINGDAO YUNTIAN BIOTECH
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