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A Fast Imaging Method of Contrast-enhanced Ultrasound Perfusion Parameters

A technology of contrast-enhanced ultrasound and imaging methods, which is applied in ultrasound/acoustic/infrasonic diagnosis, acoustic diagnosis, infrasonic diagnosis, etc. It can solve the problems of large TIC interference, limited application of imaging algorithms, and long running time of perfusion parameter imaging algorithms, etc.

Active Publication Date: 2016-08-17
XI AN JIAOTONG UNIV
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Problems solved by technology

However, the perfusion parameter imaging algorithm takes a long time to run, TIC is greatly disturbed, and the requirements for equipment are high, which limits the further application of imaging algorithms.

Method used

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  • A Fast Imaging Method of Contrast-enhanced Ultrasound Perfusion Parameters
  • A Fast Imaging Method of Contrast-enhanced Ultrasound Perfusion Parameters
  • A Fast Imaging Method of Contrast-enhanced Ultrasound Perfusion Parameters

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Embodiment Construction

[0057] The present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.

[0058] Although published patents or literature, such as high-resolution and high-quality contrast-enhanced ultrasound perfusion parameter images obtained under a single-pixel TIC source (for example, application number: 201510100876.8, a contrast-enhanced ultrasound perfusion parameter imaging based on a single-pixel TIC source method), but due to the limitation of the complexity of the algorithm, its running time is long, and it has high requirements on the software and hardware level of the equipment. Therefore, the present invention first proposes a quantitative evaluation method of perfusion parameter imaging, comprising the following steps:

[0059] (1) Using image information entropy (InEn C ), image average contrast (AC C ), image average gray level (AG), image color uniformly distributed area noise (SD C ) four quantitative evaluation inde...

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Abstract

The present invention provides a fast imaging method of contrast-enhanced ultrasound perfusion parameters: input the contrast-enhanced ultrasound image of the perfusion process, and select a certain frame of image as the background display image of the perfusion parameter; select the region of interest and extract 3×3 to 5×5 pixel neighborhoods After smoothing the TIC of each point, the effective TIC is screened and the baseline is zeroed in turn; the time-type, intensity-type and ratio-type perfusion parameter matrix of the TIC matrix is ​​extracted, and pseudo-color coding is performed; the pseudo-color parameter image information entropy, average contrast The quantitative evaluation model of multivariate contrast-enhanced ultrasound perfusion parameters imaging was constructed by using the average gray level and uniform color distribution area noise, and the perfusion parameter images obtained were evaluated. Compared with other disclosed perfusion parameter imaging methods, the present invention not only obtains perfusion parameter image quality equivalent to the disclosed method, but also greatly reduces computing time and improves imaging efficiency by 71.6±5.2%.

Description

technical field [0001] The invention belongs to the field of contrast-enhanced ultrasound imaging, and in particular relates to an imaging method of contrast-enhanced ultrasound perfusion parameters and a quantitative evaluation method. Background technique [0002] Contrast-enhanced ultrasound perfusion parameter imaging technology transforms the conventional contrast-enhanced ultrasound sequence image into a color map containing the time distribution characteristics of the entire microvascular perfusion for intuitive spatial display, which can reflect the space of functional blood perfusion information such as blood flow velocity and blood volume distributed. Through color coding, using pseudo-color changes to highlight details, increase the dynamic range of images, and facilitate the identification and diagnosis of clinicians. It is of great significance and value for clinical diagnosis and treatment evaluation. [0003] Contrast-enhanced ultrasound perfusion parametric ...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B8/00
Inventor 万明习王弟亚肖梦楠杨萱钟徽
Owner XI AN JIAOTONG UNIV