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Traditional Chinese medicine gel capable of promoting skin wound to heal and preparation method of traditional Chinese medicine gel

A technology of wound healing and gel, which is applied in the field of embodiments, can solve the problems of not strict quality control standards, inability to reduce trauma pain, poor control of infection, etc.

Inactive Publication Date: 2016-01-20
陈远征
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, the use of disinfectants (iodine, etc.) and band-aids can play a role in sterilization and disinfection, but it cannot reduce trauma pain; external use of lidocaine cream and aerosol can play an analgesic effect, but it is poor in controlling infection; Traditional Chinese medicine extracts are the main drug, most of which are medical devices, and the quality control standards are not strict; most of the external drug dosage forms are ointment and liniment, which is inconvenient to administer

Method used

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  • Traditional Chinese medicine gel capable of promoting skin wound to heal and preparation method of traditional Chinese medicine gel

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Experimental program
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Effect test

Embodiment 1

[0082] Gel composition: Carbomer 940 2.6%, hydroxypropyl methylcellulose 1.4%, lauroazepine 1.5%, polysorbate-80 2.5%, triethanolamine 1.4%, glycerin 7.5%, methyl hydroxybenzoate 0.3 %, traditional Chinese medicine clear ointment 10%, the balance is water;

[0083] Prescription of traditional Chinese medicine clear ointment: 15 parts of Hypericum perforatum, 12 parts of Featherweed, 10 parts of Liangmianzhen, 12 parts of Dixie, 25 parts of Fufangteng, 10 parts of Hibiscus, 14 parts of Bletilla striata

[0084]The preparation method of the gel: take Hypericum perforatum, Feathergrass, L. chinensis, Dixie, Fufangteng, hibiscus, and Bletilla striata, add water to decoct 2 to 3 times, and the amount of water added each time is 6% of the weight of the raw material medicine. ~10 times, decocting time is 1~2 hours, filter; combine filtrate, leave standstill, take supernatant and concentrate to relative density to be 1.12 (60 ℃ measure), add ethanol to make the volume percentage conte...

Embodiment 2

[0087] Gel composition: Carbomer 940 1.8%, hydroxypropyl methylcellulose 1.6%, lauroazepine 1.3%, polysorbate-80 25%, triethanolamine 1.7%, glycerin 8%, methyl paraben 0.45%, traditional Chinese medicine clear ointment 7%, and the remainder is water.

[0088] Prescription of traditional Chinese medicine clear ointment: 15 parts of Hypericum perforatum, 12 parts of Featherweed, 10 parts of Liangmianzhen, 12 parts of Dixie, 25 parts of Fufangteng, 10 parts of Hibiscus, 14 parts of Bletilla striata

[0089] The preparation method of the gel: take the raw materials, add water and decoct 2 to 3 times, the amount of water added each time is 6 to 10 times the weight of the raw material medicine, and the decoction time is 1 to 2 hours, then filter; combine the filtrates, statically Place, take the supernatant and concentrate to a relative density of 1.10 (measured at 60°C), add ethanol to make the volume percentage of ethanol reach 75%, after stirring evenly, let the alcohol settle do...

Embodiment 3

[0092] Gel composition: Carbomer 940 3.0%, hydroxypropyl methylcellulose 1.5%, lauroazepine 2.2%, polysorbate-80 3.0%, triethanolamine 2.9%, glycerin 6.5%, methyl hydroxybenzoate 0.25% %, traditional Chinese medicine clear ointment 12%, and the remainder is water.

[0093] Prescription of traditional Chinese medicine clear ointment: 15 parts of Hypericum perforatum, 12 parts of Featherweed, 10 parts of Liangmianzhen, 12 parts of Dixie, 25 parts of Fufangteng, 10 parts of Hibiscus, 14 parts of Bletilla striata

[0094] The preparation method of the gel: take the raw materials, add water and decoct 2 to 3 times, the amount of water added each time is 6 to 10 times the weight of the raw material medicine, and the decoction time is 1 to 2 hours, then filter; combine the filtrates, statically Place, take the supernatant and concentrate to a relative density of 1.15 (measured at 60°C), add ethanol to make the volume percentage of ethanol reach 77%, after stirring evenly, let the alc...

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Abstract

The invention belongs to the field of traditional Chinese medicine, discloses a traditional Chinese medicine gel capable of promoting a skin wound to heal and is characterized by comprising a high molecular material, a penetration enhancer, a surfactant, a pH modifier, a preservative, water and traditional Chinese medicine clear paste prepared through raw materials of hyperforin perforatum, herb of denseleaf crazyweed, radix zanthoxyli, herb of thymeleaf speed welt, euonymus fortunei, hibiscus mutabilis and bletilla striata. According to the Chinese medicine gel capable of promoting the skin wound to heal, all medicine interacts collaboratively, stasis can be eliminated to subdue swelling, heat and toxic materials can be cleaned away, and effects of antisepsis and anti-inflammation as well as removing necrotic tissue and promoting granulation are realized. The effects of rapidly relieving patient's pain, rapidly healing the wound, removing blood stasis for promoting tissue regeneration and activating blood and dissipating stasis are realized; besides, the traditional Chinese medicine gel is uniform and fine and easy to coat after folding, the residence time is long, skin won't be tightened, the gel is stable to release, the stability is good, no toxic or side effect exists, the obedience of a patient for receiving treatment is improved greatly, and the life quality of the patient is improved.

Description

technical field [0001] The embodiment of the present invention specifically discloses a traditional Chinese medicine gel for promoting skin wound healing and a preparation method thereof. Background technique [0002] From ancient times to the present, skin wounds and injuries are common clinical diseases in surgery. For example, burns, various traumas, skin ulcers, and mucous membrane injuries are all surgical wounds. If they are not treated in time, pathogens and bacteria will invade, which will not only expand the wound , skin ulceration, and even infection, resulting in sepsis, leading to death. Wound repair has always been one of the research hotspots in the field of surgery. Wound healing is a pathological process caused by trauma, which is a complex and highly coordinated process involving a variety of growth factors, cytokines, inflammatory cells and repair cells. The process of wound healing is complex and affected by many factors. In addition to fibroblasts, infl...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/06A61K47/38A61K47/32A61P17/02
Inventor 陈远征
Owner 陈远征
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