Test strip for fast detection of drug residue of amantadine

Abstract

The invention provides a test strip, and belongs to the field of food safety fast detection. The test strip comprises a baseplate, a sample cushion, a conjugate release cushion, a reaction film and a water-absorbing cushion, wherein the sample cushion, the conjugate release cushion, the reaction film and the water-absorbing cushion are adhered onto the baseplate and in tight contact with one another sequentially; part of the conjugate release cushion is coated with the sample cushion; the reaction film is coated with detection lines made of amantadine-carrier protein conjugate and quality control lines made of goat anti-mouse IgG; the conjugate release cushion is coated with a colloid gold marker made of amantadine. The test strip has the advantages that the observing time of a detection result can be prolonged; the sample absorption cushion can sufficiently absorb a detection solution and be in full contact with a gold-labelled antibody for full reaction, and then chromatography is conducted on the reaction film for reaction, so that error can be reduced effectively. The test strip can be used for further preventing protein in the gold-labelled antibody from losing activity under the action of certain interference ingredients in a detection sample, so that the impact on the combination of the gold-labelled antibody and a coating antigen is avoided.

Description

technical field [0001] The invention relates to a rapid detection test strip for detecting amantadine drug residues, belonging to the field of rapid detection of food safety. technical background [0002] Amantadine is the earliest antiviral drug used to suppress influenza virus. It was approved as a preventive drug in the United States in 1966 when the Asian cold was prevalent. And in 1976, it was confirmed as a therapeutic drug on the basis of a preventive drug. The efficacy and safety of the drug on adult patients have been widely recognized. However, the therapeutic dose is very close to the dose that produces side effects, and it is difficult to determine the dose and administration plan for the elderly and those with chronic cardiopulmonary disease or kidney disease, so it has not been widely used in clinical practice. In Japan, amantadine has been used as a treatment drug for Parkinson's disease, and it was not approved for the treatment of influenza virus type A in...

AI Technical Summary

Problems solved by technology

[0006] In 2005, the Chinese government's "Announcement of the Ministry of Agriculture (No. 560)" also clearly pointed out that "amantadines and other antiviral drugs for human transplantation lack scientific norms and safe and effective experimental data. Animal disease control brings adverse consequences and affects the implementation of national animal disease prevention and control policies

The reason is that the price is low, but if it is used inappropriately, it will cause it to remain in the poultry or the bird flu virus will mutate, and it will cause harm to the human body after eating it.

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