Pharmaceutical composition containing folium artemisiae argyi for treating solar dermatitis

A composition and drug technology, applied in the direction of drug combination, medical preparations containing active ingredients, skin diseases, etc., can solve the problems of skin organ damage, unsatisfactory, and inability to comprehensively prevent and treat solar dermatitis, so as to achieve less recurrence , less side effects, better effect of drug treatment

Inactive Publication Date: 2016-02-10
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of these drugs are hormonal drugs. Long-term use will not only cause certain damage to the skin or other organs, but also cannot fundamentally change the skin quality sensitive to sunlight.
In addition, there are a small amount of traditional Chinese medicine compositions used for the treatment of solar dermatitis, which have achieved therapeutic effects to varying degrees, but are not ideal
[0005] Chinese patent application 201410113112.8 discloses a traditional Chinese medicine composition for treating solar dermatitis, which is prepared from the fol

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] The pharmaceutical composition of Example 1 of the present invention is prepared from the following raw materials in parts by weight: 6 parts of Gastrodia elata, 5 parts of Artemisia argyi, 8 parts of Gardenia, 10 parts of Rehmannia glutinosa, 5 parts of chrysanthemum, 6 parts of Houttuynia cordata, and 3 parts of peppermint , 6 parts of red peony, 5 parts of forsythia, 10 parts of notopterygium, 9 parts of Chuanxiong, 5 parts of Moutan bark, 6 parts of nepeta, 7 parts of Pinellia, 4 parts of Sophora flavescens and 5 parts of licorice.

[0045] The preparation method is as follows:

[0046] S1 Gastrodia elata was washed, dried, crushed, passed through a 80-mesh sieve, added 5 times the weight of Gastrodia elata coarse powder with a volume fraction of 75% ethanol, soaked for 10 hours, ultrasonically extracted twice at 55°C, 40 minutes each time, ultrasonically The frequency is 25kHz, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a c...

Embodiment 2

[0050] The pharmaceutical composition of Example 2 of the present invention is prepared from the following raw materials in parts by weight: 12 parts of Gastrodia elata, 15 parts of Artemisia argyi, 16 parts of Gardenia, 15 parts of Rehmannia glutinosa, 10 parts of chrysanthemum, 10 parts of Houttuynia cordata, 6 parts of mint , 12 parts of red peony, 15 parts of forsythia, 20 parts of notopterygium, 15 parts of Chuanxiong, 15 parts of Moutan bark, 9 parts of nepeta, 9 parts of Pinellia, 14 parts of Sophora flavescens and 12 parts of licorice.

[0051] The preparation method is as follows:

[0052] S1 Gastrodia elata was washed, dried, crushed, passed through a 100-mesh sieve, added 80% ethanol with a volume fraction 6 times the weight of Gastrodia elata coarse powder, soaked for 11 hours, ultrasonically extracted twice at 60°C, 45 minutes each time, ultrasonically The frequency is 30kHz, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a cl...

Embodiment 3

[0056] The pharmaceutical composition of Example 3 of the present invention is prepared from the following raw materials in parts by weight: 10 parts of Gastrodia elata, 12 parts of Artemisia argyi, 12 parts of Gardenia, 11 parts of Rehmannia glutinosa, 6 parts of chrysanthemum, 8 parts of Houttuynia cordata, and 4 parts of mint , 10 parts of red peony, 13 parts of forsythia, 15 parts of notopterygium, 12 parts of Chuanxiong, 10 parts of Moutan bark, 7 parts of nepeta, 8 parts of Pinellia, 10 parts of Sophora flavescens and 10 parts of licorice.

[0057] The preparation method is as follows:

[0058] S1 Gastrodia elata was washed, dried, crushed, passed through a 100-mesh sieve, added 8 times the weight of Gastrodia elata coarse powder with 80% ethanol, soaked for 12 hours, ultrasonically extracted twice at 65°C, 50 minutes each time, ultrasonically The frequency is 35kHz, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a clear paste with a...

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PUM

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Abstract

The invention belongs to the field of traditional Chinese medicines, and relates to a pharmaceutical composition containing folium artemisiae argyi for treating solar dermatitis. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 6-12 parts of gastrodia elata, 5-15 parts of folium artemisiae argyi, 8-16 parts of fructus gardeniae, 10-15 parts of dried rehamnnia root, 5-10 parts of chrysanthemum flowers, 6-10 parts of houttuynia cordata, 3-6 parts of mint, 6-12 parts of radix paeoniae rubra, 5-15 parts of fructus forsythiae, 10-20 parts of notopterygium root, 9-15 parts of rhizoma chuanxiong, 5-15 parts of moutan bark, 6-9 parts of schizonepeta, 7-9 parts of pinellia ternata, 4-14 parts of radix sophorae flavescentis, and 5-12 parts of licorice root. The pharmaceutical composition has the efficacies of clearing away heat and toxic materials, treating skin and resisting allergy, dispersing blood stasis and dredging collaterals, diminishing inflammation and relieving itching, as well as clearing damp and eliminating diseases, and also has the advantages of good curative effects, small side effects, small possibility of relapse, and simplicity in popularization and application.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a medicinal composition containing mugwort leaves for treating solar dermatitis. Background technique [0002] Solar dermatitis is solar dermatitis, also known as sunburn or sunburn, which is an acute inflammatory reaction of normal skin after exposure to the sun, manifested as erythema, edema, blisters, pigmentation, and desquamation. It is an allergic skin disease caused by light that occurs in exposed areas. The principle is: normal skin is irradiated by ultraviolet rays to cause various cells in the dermis to release inflammatory mediators such as histamine, 5-hydroxytryptamine, and kinin, so that the blood vessels in the dermis expand and the permeability increases. In spring and summer, the active spectrum of this disease is mainly UVB. Normal skin is irradiated by ultraviolet rays to make various cells in the dermis release inflammatory mediators such as hista...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61P17/00
Inventor 王一飞刘秋英任哲利奕成
Owner JINAN UNIVERSITY
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