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Composition with anticorrosion effect and preparation method and application thereof
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A technology of composition and efficacy, which can be used in medical preparations containing active ingredients, preparations for skin care, pharmaceutical formulas, etc., and can solve problems such as sensitization and toxicology disputes and human skin damage
Inactive Publication Date: 2016-02-24
张愉 +1
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Abstract
Description
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Problems solved by technology
At present, preservatives commonly used in cosmetics include parabens, imidazolidinyl urea, hydantoin, isothiazolinone, etc. These preservatives have certain damage to human skin and are potentially sensitizing or even toxic. manage disputes
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Embodiment 1
[0010] A composition (1) with antiseptic effect of the present embodiment is composed as follows by weight percentage: 0.5% caprylyl hydroxamic acid, 15% 1,2-hexanediol, 30% p-hydroxyacetophenone, butanediolAlcohol or glycerin is the balance, butanediol or glycerin is only used as a solvent, the effect is the same, and the amount of solvent does not affect the antiseptic effect.
[0011] A method for preparing a composition (1) with antiseptic effect, the p-hydroxyacetophenone, butanediol or glycerol in the above examples are dissolved in each other at 80°C, stirred evenly, and then cooled to 60°C, Add caprylyl hydroxamic acid and 1,2-hexanediol, stir evenly, and dissolve.
Embodiment 2
[0013] A composition (2) with antiseptic effect of the present embodiment is composed as follows by weight percentage: caprylyl hydroxamic acid 2%, 1,2-hexanediol 5%, p-hydroxyacetophenone 10%, butanediol Alcohol or glycerin is the balance, butanediol or glycerin is only used as a solvent, the effect is the same, and the amount of solvent does not affect the antiseptic effect.
[0014] A preparation method of the composition (2) with antiseptic effect, the p-hydroxyacetophenone, butanediol or glycerol in the above-mentioned examples are mutually dissolved at 80°C, stirred evenly, and then cooled to 60°C, Add caprylyl hydroxamic acid and 1,2-hexanediol, stir evenly, and dissolve.
Embodiment 3
[0016] A composition (3) with antiseptic effect of the present embodiment is composed as follows by weight percentage: 1.8% caprylyl hydroxamic acid, 10% 1,2-hexanediol, 28% p-hydroxyacetophenone, butanediol Alcohol or glycerin is the balance, butanediol or glycerin is only used as a solvent, the effect is the same, and the amount of solvent does not affect the antiseptic effect.
[0017] A preparation method (3) of a composition with antiseptic effect, the p-hydroxyacetophenone, butanediol or glycerol in the above-mentioned examples are mutually dissolved at 80°C, stirred evenly, and then cooled to 60°C, Add caprylyl hydroxamic acid and 1,2-hexanediol, stir evenly, and dissolve.
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Abstract
The invention discloses a composition with an anticorrosion effect. The composition comprises, by weight, 0.5-2% of caprylhydroxamic acid, 5-15% of 1,2-hexanediol, 10-30% of p-hydroxyacetophenone and the rest of butylene glycol or glycerol. A preparation method of the composition comprises the following steps: letting p-hydroxyacetophenone and butylene glycol or glycerol be soluble with each other and uniformly stirring, cooling to 60 DEG C, adding caprylhydroxamic acid and 1,2-hexanediol, uniformly stirring, and dissolving. Application of the composition: dosage of the composition in cosmetic is 1.5-2%. The composition of the invention has an anticorrosion effect, is nonirritating, and has high safety.
Description
technical field [0001] The present invention relates to the field of application of compositions with antiseptic effect, in particular to a composition of polyalcohol with antiseptic effect, chelating agent and antioxidant used in cosmetics and its preparation method and application. Background technique [0002] At present, cosmetics are rich in nutrients, which are especially suitable for the growth of microorganisms. Therefore, preservatives need to be added to cosmetics. The purpose of adding preservatives is to inhibit the growth and reproduction of microorganisms, avoid deterioration of cosmetics, and maintain freshness and effectiveness. . [0003] my country's Hygienic Standards for Cosmetics (2007 Edition) has planned 67 kinds of preservatives and their use limits that can be used in cosmetics. At present, preservatives commonly used in cosmetics include parabens, imidazolidinyl urea, hydantoin, isothiazolinone, etc. These preservatives have certain damage to human...
Claims
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Application Information
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