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Polyurethane dressing for trauma hemostasis and preparation method thereof

A polyurethane and trauma technology, applied in the field of medical materials, can solve the problems of wound dressing adhesion, easy breeding of bacteria, hindering epithelialization, etc., and achieve the effect of preventing secondary trauma, strict proportioning of traditional Chinese medicine, and preventing infection

Inactive Publication Date: 2016-04-20
王书美
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional wound dressings (such as gauze and cotton) have many disadvantages: they are easy to breed bacteria, and the wound exudate is easy to form scabs with dry dermal tissue, which hinders epithelialization; at the same time, the wound is easy to stick to the dressing, causing pain when changing the dressing , causing secondary trauma

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Example 1 Polyurethane dressing for trauma hemostasis, mainly prepared from the following raw materials (10g each): 30 parts of polyethylene glycol, 1 part of glycerin, 20 parts of diphenylmethane diisocyanate, 12 parts of polyether, 5 parts of chloroform, 1 part of tetramethylpropanediamine, 6 parts of baicalin, 8 parts of notopterygium, 12 parts of thistle, 10 parts of Zizhucao, 6 parts of catechu, 4 parts of fresh rehmannia glutinosa, 3 parts of alum, 5 parts of Luo Kui, 8 parts of radish , 6 parts of burdock seeds.

[0028] The preparation method of above-mentioned wound hemostasis polyurethane dressing is:

[0029] (1) Take large thistle and baicalin to remove impurities, put them into boiling white wine, heat for 10 minutes, take out, put hot sand in a frying pan and stir-fry until flexible, add raw materials and stir-fry until the surface bulges, take it out, and let it dry cold;

[0030] (2) Take notopterygium and Luokui to remove impurities, soak them in hot...

Embodiment 2

[0034] Example 2 Polyurethane dressing for trauma hemostasis, mainly prepared from the following raw materials (10g each): 40 parts of polyethylene glycol, 3 parts of glycerin, 40 parts of diphenylmethane diisocyanate, 18 parts of polyether, 11 parts of chloroform, 4 parts of stannous 2-ethylhexanoate, 10 parts of skullcap, 10 parts of notopterygium, 20 parts of thistle, 13 parts of Zizhucao, 11 parts of catechu, 9 parts of fresh rehmannia, 6 parts of alum, 8 parts of Luo Kui, radish 11 parts, 10 parts of burdock.

[0035] The preparation method of polyurethane dressing for trauma hemostasis is:

[0036] (1) Take large thistle and baicalin to remove impurities, put them into boiling white wine, heat for 10 minutes, take out, put hot sand in a frying pan and stir-fry until flexible, add raw materials and stir-fry until the surface bulges, take it out, and let it dry cold;

[0037](2) Take notopterygium and Luokui to remove impurities, soak them in hot milk, take them out, d...

Embodiment 3

[0042] Example 3 Polyurethane dressing for trauma hemostasis, mainly prepared from the following raw materials (10g each): 32 parts of polyethylene glycol, 1.5 parts of glycerin, 25 parts of diphenylmethane diisocyanate, 13 parts of polyether, 6 parts of chloroform, 2 parts of hydroxyethylpropylene diamine, 7 parts of skullcap, 8.5 parts of notopterygium, 14 parts of thistle, 11 parts of Zizhucao, 7 parts of catechu, 5 parts of fresh rehmannia, 4 parts of alum, 6 parts of Luo Kui, radish 9 parts, 7 parts of burdock.

[0043] The preparation method of polyurethane dressing for trauma hemostasis is:

[0044] (1) Take large thistle and baicalin to remove impurities, put them into boiling white wine, heat for 10 minutes, take out, put hot sand in a frying pan and stir-fry until flexible, add raw materials and stir-fry until the surface bulges, take it out, and let it dry cold;

[0045] (2) Take notopterygium and Luokui to remove impurities, soak them in hot milk, take them out...

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Abstract

The invention discloses a polyurethane dressing for trauma hemostasis. The polyurethane dressing is mainly prepared from, by mass, 30-40 parts of polyethylene glycol, 1-3 parts of glycerinum, 20-40 parts of methylene diphenyl diisocyanate, 12-18 parts of polyether, 5-11 parts of trichloromethane, 1-4 parts of catalyst, 6-10 parts of scutellaria baicalensis, 8-10 parts of notopterygium roots, 12-20 parts of circium japonicum, 10-13 parts of Callicarpa macrophylla Vahl, 6-11 parts of acacia catechu, 4-9 parts of fresh radix rehmanniae, 3-6 parts of alumen, 5-8 parts of red vinespinach leaf or herb, 8-11 parts of Raphanus sativus L and 6-10 parts of fructus arctii. The polyurethane dressing has good hydrophily, can absorb bleeding blood and seepage of wounds, and is good in hemostasis effect. Effective ingredients in traditional Chinese medicinal materials are effectively extracted, wound healing can be promoted, infection can be avoided, the polyurethane dressing does not adhere to the wound surfaces, and is easy to replace, and secondary trauma is avoided.

Description

technical field [0001] The invention relates to the field of medical materials, in particular to a polyurethane dressing for trauma hemostasis and a preparation method. Background technique [0002] In recent decades, with the proposal of the "moist healing" theory of wounds and the development of biomaterials, new dressings, especially new polyurethane dressings, have emerged continuously. Traditional wound dressings (such as gauze and cotton) have many disadvantages: they are easy to breed bacteria, and the wound exudate is easy to form scabs with dry dermal tissue, which hinders epithelialization; at the same time, the wound is easy to stick to the dressing, causing pain when the dressing is lifted , causing secondary trauma. The new polyurethane dressing can keep the wound moist and control the water vapor transmission rate. And resist the invasion of bacteria: its spongy porous layered structure is conducive to the discharge of wound secretions. Promote the healing o...

Claims

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Application Information

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IPC IPC(8): A61L15/26A61L15/44A61K36/85A61P17/02A61P7/04A61K33/06
CPCA61L15/26A61K33/06A61K36/185A61K36/237A61K36/28A61K36/31A61K36/48A61K36/539A61K36/804A61K36/85A61K2236/33A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61L15/44A61L2300/30A61L2300/404C08L75/08A61K2300/00
Inventor 不公告发明人
Owner 王书美
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