Magnetization transfer contrast technique for chemical exchange saturation transfer (cest) mri by localized steam and method of operation thereof

A kind of magnetic resonance, part of the technology, applied in the field of MRI system, can solve the problem of non-uniformity, limitation and so on

Inactive Publication Date: 2016-05-11
KONINKLJIJKE PHILIPS NV
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  • Abstract
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  • Claims
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Problems solved by technology

In addition, the sensitivity of conventional CESTMRI i

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  • Magnetization transfer contrast technique for chemical exchange saturation transfer (cest) mri by localized steam and method of operation thereof
  • Magnetization transfer contrast technique for chemical exchange saturation transfer (cest) mri by localized steam and method of operation thereof
  • Magnetization transfer contrast technique for chemical exchange saturation transfer (cest) mri by localized steam and method of operation thereof

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Embodiment Construction

[0017] The following is a description of illustrative embodiments in which the above-mentioned features and advantages, as well as other features and advantages, will emerge when taken in conjunction with the following figures. In the following description, illustrative details such as architectures, interfaces, technologies, element attributes, etc. are set forth for purposes of explanation and not limitation. However, one of ordinary skill in the art will appreciate that other embodiments than these details are still to be understood within the scope of the claims. Moreover, for the purpose of clarity, detailed descriptions of well-known devices, circuits, tools, techniques and methods are omitted so as not to obscure the description of the present system. It should be expressly understood that the drawings are included for purposes of illustration and do not represent the entire scope of the present system. In the drawings, like reference numerals in different drawings may...

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Abstract

A magnetic resonance imaging (MRI) system (600),for acquiring magnetic resonance (MR) information of a volume, includes at least one controller (610) configured generate at least a portion of a stimulated echo acquisition mode (STEAM) CESTsequence including first through third 90degree radio frequency (RF) pulses, and a first pulse train situated before the first 90degree RF pulse. The first pulse train has first number of pulses. The controller (610) is further configured to generate at least another portion of the STEAM CEST sequence comprising a second pulse train situated between the second and third 90degree RF pulses, the second pulse train comprising a second number of pulses which is less than the first number of pulses;generating end of spoil gradients;and/or to acquire MR information during an acquisition window which is stated at least partially after the end of spoil gradients.

Description

technical field [0001] Embodiments of the present disclosure relate to a magnetic resonance imaging (MRI) system that acquires image information using a nuclear magnetic resonance (NMR) method, and more particularly, to a magnetization transfer ( MT) contrast technique to enhance the MRI system and method of operation of the magnetization contrast. Background technique [0002] CESTMRI is an MT contrast technique in which exogenous or endogenous compounds containing exchangeable protons or exchangeable molecules are selectively saturated and, thereafter, indirectly detected by a water signal with enhanced sensitivity to the exogenous or endogenous Compounds were tested (see R1, R2). Can extend the application of CESTMRI to such as oncology research (e.g. amide proton transfer (APT) (see R3)), ischemic heart disease research, myocardial infarction research (e.g. creatine MT spectroscopy (see R4)), sugar In the field of study of original quantification (glycoCEST) studies an...

Claims

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Application Information

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IPC IPC(8): G01R33/56
CPCG01R33/5605G01R33/288G01R33/4833G01R33/5617
Inventor B·杨
Owner KONINKLJIJKE PHILIPS NV
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