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Composite patch with anti-adhesion pouch skirt

An anti-adhesion and soft film technology, which is applied in the field of composite patches, can solve problems such as easy delamination, high cost, and cumbersome preparation process, and achieve the effects of reducing adhesion, good compliance, and low foreign body sensation

Active Publication Date: 2018-03-06
TRANSEASY MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation of this product has gone through many chemical reactions, which is relatively complicated and adds a large cost to the production process.
[0007] The above products may have problems such as cumbersome preparation process, many chemical reactions, easy delamination, easy to cause serous swelling, affect the healing of tissue and repair materials, and have controversial anti-adhesion effects

Method used

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  • Composite patch with anti-adhesion pouch skirt
  • Composite patch with anti-adhesion pouch skirt
  • Composite patch with anti-adhesion pouch skirt

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The manufacturing process of the composite patch with anti-adhesion soft membrane skirt according to the present invention will be described in detail below with a specific example. Described manufacturing process specifically comprises the following steps:

[0041] 1. Solution preparation

[0042] 1.1 Materials: PLCL pellets, acetone.

[0043] 1.2 Apparatus: 1000ml volumetric flask, 250ml measuring cylinder, 250ml Erlenmeyer flask.

[0044] 1.3 Environment: Class 100,000 clean workshop

[0045] 1.4 Equipment dry heat sterilization, 165 ℃, 2 hours. Rinse with acetone before use.

[0046] 1.5 Take the PLCL pellets, open it at room temperature, pour it into a 1000ml volumetric flask, add acetone to make the volume to 1000ml, cover the bottle tightly and place it at 40°C to dissolve for 48-72 hours, shake and shake during the period, and use it as a film-making PLCL solution for later use (PLCL concentration: 0.1 g / ml).

[0047] 1.6 Take 100ml of film-making PLCL sol...

Embodiment 2

[0108] 1. Solution preparation

[0109] 1.1 Materials: PLCL, MPEG2000-PLLA6000, acetone.

[0110] 1.2 Apparatus: 1000ml volumetric flask, 250ml measuring cylinder, 250ml Erlenmeyer flask.

[0111] 1.3 Environment: Class 100,000 clean workshop

[0112] 1.4 Equipment dry heat sterilization, 165 ℃, 2 hours. Rinse with acetone before use.

[0113] 1.5 Prepare 10, 30 or 50 grams of MPEG2000-PLLA6000, open it at room temperature, pour it into a 1000ml volumetric flask, add acetone, cap the bottle tightly and place it at 40°C to dissolve, then add 90, 70, 50 grams of PLCL and stir to dissolve completely , and add acetone to make it to 1000mL, and use it as a film-making mixed solution (the mass ratios of PLCL and MPEG2000-PLLA6000 are 9:1, 7:3, and 1:1, respectively).

[0114] 1.6 Take 100ml of film-making mixed solution and add it to a 250ml Erlenmeyer flask, then add 100ml of acetone, cap the bottle tightly and shake well, and use it as a coating mixed solution for later use. ...

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Abstract

The invention relates to a complex patch provided with an anti-adhesion soft membrane skirt, belonging to the technical field of medical consumables. The complex patch provided with the anti-adhesion soft membrane skirt comprises a polypropylene mesh and an absorbable membrane layer, wherein the surface of the polypropylene mesh is dipcoated with an absorbable coating, and the absorbable membrane layer is laminated on the polypropylene mesh; the area of the absorbable membrane layer is larger than that of the polypropylene mesh, so that the absorbable membrane layer skirt is formed around the polypropylene mesh. Compared with hot-pressing or molding by casting, the anti-adhesion patch enables polypropylene and the anti-adhesion membrane to be completely nested with each other, and microscopic examination proves that no obvious boundary surface exists, so that the phenomenon of stratification does not occur. The anti-adhesion patch is suitable for itra-abdominal herniorrhaphy of abdominal hernia and abdominal wall defect as well as itra-abdominal herniorrhaphy of laparoscopic inguinal hernia.

Description

technical field [0001] The invention relates to the technical field of medical consumables, and more specifically, the invention relates to a composite patch with an anti-adhesion soft film skirt. Background technique [0002] A hernia is a fascial defect in a structure, such as the abdominal wall, through which an organ or part of an organ, tissue or part of a tissue can protrude. Usually it involves a weakening, bulging or actual tearing of the fascia that normally structurally contains the organ or tissue. There are many types of hernias. For example, when in the lower abdominal region, hernias often contain intra-abdominal contents, such as bowel or other tissue, that enter or pass through a defect in the abdominal wall. Mesh mesh is widely used in hernia repair. Currently commonly used hernia repair sheets are polyester mesh (such as Dacron, Mersilene) and polypropylene mesh (such as Marlex, Prolene, etc.). However, pure non-degradable mesh cannot be used for intrap...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/00A61M27/00A61L31/04A61L31/14
CPCA61F2/0063A61L31/048A61L31/14A61M27/002C08L23/12
Inventor 孙杰陈凡何建庆孟庆怡乔红英
Owner TRANSEASY MEDICAL TECH
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