Traditional Chinese medicine composition for improving cerebral small vessel disease cognition impairment and preparation method and application thereof

A technology for cognitive dysfunction and cerebral small blood vessels, applied in the field of medicine, can solve problems such as lack of interventions, measures and methods, and achieve the effects of simple and feasible preparation method, delaying the development of disease course and having practical value

Inactive Publication Date: 2016-06-15
霍清萍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above studies all show that the intervention of cerebrovascular disease has been studied before, but there is a lack of effective intervention, measures and methods from mild cognitive impairment to severe cognitive impairment, and finally develops into dementia

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] The traditional Chinese medicine composition Bushen Huayu prescription for improving cognitive dysfunction in patients with cerebral small vessel disease in this example is water extract, and the raw materials are weighed according to the following proportions: 40 grams of Cistanche, 24 grams of Dilong, and 20 grams of Danshen , 20 grams of turmeric, 24 grams of Yizhi kernel; then soak in water 3 to 4 cm higher than the raw materials for 0.5 to 1 hour; Aqueous extracts were obtained.

Embodiment 2

[0050] The traditional Chinese medicine composition used to improve the cognitive dysfunction of patients with cerebral small vessel disease in this embodiment is a water extract, and the raw materials are weighed according to the following proportions: 20 grams of Cistanche, 12 grams of Dilong, 10 grams of Salvia miltiorrhiza, 10 grams of Curcuma 12 grams of Yizhi kernels; then soaked in water 3 to 4 cm higher than the raw material for 0.5 to 1 hour; then boiled with a strong fire, decocted with a slow fire until 150 to 200 ml, removed the residue and extracted the juice, and obtained the water extract things.

Embodiment 3

[0052] The traditional Chinese medicine composition used to improve the cognitive dysfunction of patients with cerebral small vessel disease in this embodiment is a water extract, and the raw materials are weighed according to the following proportions: 60 grams of Cistanche, 36 grams of Dilong, 30 grams of Salvia Miltiorrhiza, 30 grams of Curcuma 36 grams of Yizhi kernels; then soaked in water 3 to 4 cm higher than the raw material for 0.5 to 1 hour; then boiled with a strong fire, decocted with a slow fire until 150 to 200 ml, removed the residue and extracted the juice, and obtained the water extract things.

[0053] Adopt the treatment situation of above-mentioned Chinese medicine composition:

[0054] Case 1, Yang, female, 56 years old, from Shanghai, had dizziness accompanied by memory loss as the first prominent symptom on January 21, 2014. She reported dizziness from time to time and obvious memory loss in the past 2 years. The total course of disease was intermittent....

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for improving cerebral small vessel disease cognition impairment and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from, by weight, 4-60 parts of herba Cistanches, 3-36 parts of pheretima, 3-30 parts of radix salviae miltiorrhizae, 3-30 parts of radix curcumae and 3-36 parts of sharpleaf galangal fruits. The traditional Chinese medicine composition can effectively improve cognition impairment of a patient suffering from cerebral small vessel disease (CVSD), delay development of disease and is small in side effect, normal work and study of the patient are not influenced during the medicine taking period, and wide popularization value is achieved. The preparation method is simple and feasible and has great practical value.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for improving cognitive dysfunction of cerebral small vessel disease. Background technique [0002] Cerebral small blood vessels are the basic units that constitute the blood supply of brain tissue and play an important role in maintaining brain function. CSVD (CerebralSmallVesselDisease) is a cerebral small vessel disease caused by various lesions. It is clinically manifested as lacunar infarction, cerebral infarction, cerebral White matter changes (WhiteMatterLesions, WML) and cerebral microbleeds (CerebralMicrobleeds, CMB) are the main features. At present, CSVD patients in my country are common in the elderly population, and stroke and dementia are the final results. [0003] Current studies believe that advanced age, high blood pressure, diabetes, abnormal lipid metabolism, and a history of transient ischemic attack (TIA) are the most impo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P25/28
CPCA61K36/64A61K35/62A61K36/537A61K36/9062A61K36/9066A61K2236/331A61K2300/00
Inventor 霍清萍
Owner 霍清萍
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