A two-dimensional honeycomb electrode array digital microfluidic chip based on ewod

Abstract

The invention discloses an EWOD (electrowetting on dielectric)-based two-dimensional digital micro-fluidic chip provided with a honeycomb electrode array. The two-dimensional digital micro-fluidic chip comprises multiple electrode layers, wherein the electrode layers are longitudinally communicated through a plurality of through holes, each electrode layer is formed by transversely connecting a plurality of drive electrodes in a shape of regular polygon, the drive electrodes have the same shape and size, the electrical property of each drive electrode is opposite to that of an adjacent electrode, the drive electrodes are tightly arranged, every drive electrode and the adjacent drive electrode are electrically insulated, nonadjacent equivalent drive electrodes are electrically connected, and equivalent drive electrodes are connected with one control electrode. The digital micro-fluidic chip has multiple advantages that the control mode is novel and simple, the array scale can be extended infinitely while the number of electrical signals is not required to be increased, the manufacturing process is simple, the drive energy is high, the batch processing degree is high, high-throughput operation is realized and the like, the defect of a conventional digital micro-fluidic chip is made up, and the practical function and the application range of the digital micro-fluidic chip are greatly broadened.

Description

technical field [0001] The invention belongs to the technical field of digital microfluidics, and relates to a digital microfluidic chip, in particular to a two-dimensional cellular electrode array digital microfluidic chip driven by electrowetting on dielectric (EWOD for short). . Background technique [0002] Digital microfluidic chip refers to a miniaturized chip that operates on discrete droplets, and is an important part of the automated control of the laboratory on a chip (LOC). The digital microfluidic chip based on the electrowetting effect on the medium mainly includes the driving and grounding electrodes, the dielectric layer, the hydrophobic layer and other parts, and uses the voltage signal to control the droplet, so it has the advantages of simple driving method, strong driving force, and easy control. It has many advantages such as convenience and high degree of automation, and has very good development prospects in the field of LOC. [0003] For the digital ...

AI Technical Summary

Problems solved by technology

However, there are currently two types of chip structures for digital microfluidic chips based on the strip electrode structure. One is that two sets of strip electrodes are placed on the lower plate of the chip, which makes the chip difficult to manufacture, complicated to control, and has problems such as easy breakdown; The second is that two sets of strip electrodes are respectively placed on the upper and lower plates. Although this can be effectively controlled, the dual-plane chip with driving electrodes on the upper plate is not easy to integrate with optical detection and other functions, which limits the application range of the chip.

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