Pharmaceutical composition capable of treating chronic constipation

A technology of chronic constipation and composition, applied in the field of medicine, can solve the problems of incomplete curative effect, difficult for ordinary patients, many side effects, etc., and achieve the effects of no toxic side effects, good therapeutic effect, and strict prescription

Inactive Publication Date: 2016-07-27
徐美英
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Western medicine has a certain curative effect on constipation, but it has many side effects and the curative effect is not thorough. Chinese medicine has rich records on the treatment of constipation. Medication, treatment based on syndrome differentiation, treating both symptoms and root causes
Patent No. ZL200410073958.X discloses a composition and preparation method with functions of laxative and detoxification, weight loss and fat reduction. It has a certain curative effect, but the materials are expensive and the cost is high, which is unbearable for ordinary patients

Method used

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  • Pharmaceutical composition capable of treating chronic constipation
  • Pharmaceutical composition capable of treating chronic constipation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1 pharmaceutical composition capsule of the present invention

[0021] Prescription: Cynomorium 18 parts, Cistanche 9 parts, tangerine peel 12 parts, bitter almond 5 parts, Polygonatum 10 parts, Ophiopogon japonicus 12 parts, Cyperus cyperi 10 parts, rhubarb 4 parts.

[0022] Preparation method: take the medicinal materials of the above weight components, add water 5-8 times the total weight of the medicinal materials, soak for 2-4 hours, decoct 1-3 times for 2-3 hours each time, filter, and combine the filtrates, The filtrate is concentrated under reduced pressure to an extract with a relative density of 1.11-1.26. The relative density is the test result at 60 degrees Celsius. Add ethanol until the alcohol content is 60-80% (v / v), refrigerate and stand for 48 hours, filter After that, the recovered ethanol was concentrated under reduced pressure into an extract. Then add a pharmaceutically acceptable carrier, and prepare into capsules by conventional method...

Embodiment 2

[0024] Embodiment 2 pharmaceutical composition granules of the present invention

[0025] Prescription: Cynomorium 18 parts, Cistanche 9 parts, tangerine peel 12 parts, bitter almond 5 parts, Polygonatum 10 parts, Ophiopogon japonicus 12 parts, Cyperus cyperi 10 parts, rhubarb 4 parts.

[0026] Preparation method: take the medicinal materials of the above weight components, add water 5-8 times the total weight of the medicinal materials, soak for 2-4 hours, decoct 1-3 times for 2-3 hours each time, filter, and combine the filtrates, The filtrate is concentrated under reduced pressure to an extract with a relative density of 1.11-1.26. The relative density is the test result at 60 degrees Celsius. Add ethanol until the alcohol content is 60-80% (v / v), refrigerate and stand for 48 hours, filter After that, the recovered ethanol was concentrated under reduced pressure into an extract. A pharmaceutically acceptable carrier is then added to prepare granules by conventional methods...

Embodiment 3

[0028] Embodiment 3 pharmaceutical composition oral liquid of the present invention

[0029] Prescription: Cynomorium 18 parts, Cistanche 9 parts, tangerine peel 12 parts, bitter almond 5 parts, Polygonatum 10 parts, Ophiopogon japonicus 12 parts, Cyperus cyperi 10 parts, rhubarb 4 parts.

[0030] Preparation method: take the medicinal materials of the above weight components, add water 5-8 times the total weight of the medicinal materials, soak for 2-4 hours, decoct 1-3 times for 2-3 hours each time, filter, and combine the filtrates, The filtrate is concentrated under reduced pressure to an extract with a relative density of 1.11-1.26. The relative density is the test result at 60 degrees Celsius. Add ethanol until the alcohol content is 60-80% (v / v), refrigerate and stand for 48 hours, filter After that, the recovered ethanol was concentrated under reduced pressure into an extract. Then add a pharmaceutically acceptable carrier, and prepare an oral liquid by a conventional...

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Abstract

The invention belongs to the field of traditional Chinese medicine, relates to a pharmaceutical composition and particularly relates to a pharmaceutical composition capable of treating chronic constipation and application of pharmaceutical composition serving as a medicine for treating chronic constipation. The pharmaceutical composition comprises the following ingredients: cynomorium songaricum, herba cistanche, pericarpium citri reticulatae, semen armeniacae amarae, radix polygonati odorati, radix ophiopogonis, rhizoma cyperi and rheum officinale. The pharmaceutical composition is simple in preparation and comprehensive in functions, has an effect of relaxing bowels, also achieves the efficacy of tonifying the kidney and the spleen, nourishing yin and generating body fluids, is capable of thoroughly conditioning the habitus of patients suffering from chronic constipation, is low in cost and free from toxic and side effects, ensures that chronic constipation is difficult to relapse after being cured, and has favorable application prospects in treating chronic constipation.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a pharmaceutical composition and its application as a medicine for treating chronic constipation. Background technique [0002] Constipation is a common complex symptom in clinical practice. It is mainly characterized by decreased frequency of defecation, decreased amount of feces, dry feces, hard defecation, or inability to defecate despite the desire to defecate, or discomfort after defecation, or anal swollen, etc. disease. If it exceeds 6 months, it is chronic constipation. With the development of society, the increase of work pressure and the single diet structure, the number of constipation patients is gradually increasing, especially in middle-aged and elderly people. Traditional Chinese medicine believes that constipation is caused by abnormal conduction in the intestines, and the disease is related to the large intestine and the spleen, stomach and kidneys. Insuffi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P1/10
CPCA61K36/8969A61K36/185A61K36/64A61K36/708A61K36/736A61K36/752A61K36/8905A61K36/8968A61K2236/331A61K2236/51A61K2300/00
Inventor 徐美英
Owner 徐美英
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