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Traditional Chinese medicinal compound for preventing and treating liver cancer and preparation method of traditional Chinese medicinal compound

A technology for traditional Chinese medicine and liver cancer, which is applied in the field of traditional Chinese medicine compound for preventing and treating liver cancer and its preparation field, can solve the problems such as the traditional Chinese medicine compound that has no effect on treating liver cancer, and achieve the effect of preventing and treating liver cancer.

Inactive Publication Date: 2016-09-07
陈芝维
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there is no traditional Chinese medicine compound with particularly significant effect on the treatment of liver cancer

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1: the preparation of active ingredient extract

[0023] Herbal formula:

[0024] Pseudostellaria, 65 parts; Nutmeg, 40 parts; Evodia, 50 parts; Coptis chinensis, 20 parts; Psoralen, 40 parts; It is 5:1.

[0025] Preparation method: Take the crude drug in the prescribed amount and extract it with 80% ethanol under hot reflux for 2 to 3 times, combine the extracts, concentrate to a density of 1.22, and spray dry to obtain the extract powder. Each gram of the extract powder is equivalent to 5g of the crude drug.

Embodiment 2

[0026] Embodiment 2: the preparation of active ingredient extract

[0027] Herbal formula:

[0028] Pseudostellariae, 60 parts; Nutmeg, 35 parts; Evodia rutaecarpa, 45 parts; Coptis chinensis, 15 parts; Psoralen, 35 parts; It is 4:1.

[0029] Preparation method: Take the crude drug in the prescribed amount and extract it with 65% ethanol under hot reflux for 2 to 3 times, combine the extracts, concentrate to a density of 1.15, and spray dry to obtain the extract powder. Each gram of the extract powder is equivalent to 4g of the crude drug.

Embodiment 3

[0030] Embodiment 3: the preparation of active ingredient extract

[0031] Herbal formula:

[0032] Pseudostellariae, 70 parts; Nutmeg, 45 parts; Evodia, 55 parts; Coptis chinensis, 25 parts; Psoralen, 45 parts; is 6:1.

[0033] Preparation method: extract the crude drug in the prescribed amount with 95% ethanol under hot reflux for 2 to 3 times, combine the extracts, concentrate to a density of 1.30, and spray dry to obtain extract powder. Each gram of extract powder is equivalent to 6g of crude drug.

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PUM

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Abstract

The invention discloses a traditional Chinese medicinal compound for preventing and treating liver cancer and a preparation method of the traditional Chinese medicinal compound. The traditional Chinese medicinal compound is prepared from the following crude medicinal materials in parts by weight: 60-70 parts of radix pseudostellariae, 35-45 parts of semen myristicae, 45-55 parts of fructus evodiae, 15-25 parts of rhizoma coptidis, 35-45 parts of fructus psoraleae, 25-35 parts of medicinal cyathula root, and 50-70 parts of bark of Phellodendron amurense Rupr. and radix angelicae pubescentis (the ratio of the weight parts of Phellodendron amurense Rupr. to radix angelicae pubescentis is (4-6) to 1). The microvessel density in the tumor can be taken as a novel tumor biological feature, which can reflect the inevitable relationship between the formation strength of the tumor microvessel and the tumor invasion. The traditional Chinese medicinal compound provided by the invention can obviously inhibit the growth of the transplantation tumor of the liver cancer, and can be developed into the medicine for treating liver cancer; and the effect of the traditional Chinese medicinal compound is possibly relevant to the ratio of the weight parts of the bark of Phellodendron amurense Rupr. to radix angelicae pubescentis.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine compound for preventing and treating liver cancer and a preparation method thereof. Background technique [0002] Liver cancer is a malignant tumor of the liver, which can be divided into two categories: primary and secondary. Primary malignant tumors of the liver originate from the epithelial or mesenchymal tissues of the liver. The former is called primary liver cancer, which is a malignant tumor with a high incidence in my country and is extremely harmful; rare. Secondary or metastatic liver cancer refers to malignant tumors originating from multiple organs throughout the body and invading the liver. Generally, it is more common in liver metastases of malignant tumors in stomach, biliary tract, pancreas, colorectum, ovary, uterus, lung, breast and other organs. [0003] The etiology and exact molecular mechanism of prima...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P35/00
CPCA61K36/36A61K36/185A61K36/21A61K36/232A61K36/487A61K36/718A61K36/754A61K36/756A61K2236/333A61K2236/39
Inventor 陈芝维
Owner 陈芝维