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Traditional Chinese medicine suppository for treating premature ovarian failure of women and preparation method thereof

A technology for premature ovarian failure and suppositories, applied in the field of traditional Chinese medicine suppositories for treating women with premature ovarian failure and its preparation, can solve the problems that are not conducive to the condition and damage the health of patients, and achieve the effect of reducing curative effect, increasing costs, and good safety

Inactive Publication Date: 2016-09-07
马佳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For physical therapy, there is also a limit, and it cannot be excessive. Excessiveness is not conducive to the condition and will damage the health of the patient.

Method used

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  • Traditional Chinese medicine suppository for treating premature ovarian failure of women and preparation method thereof
  • Traditional Chinese medicine suppository for treating premature ovarian failure of women and preparation method thereof
  • Traditional Chinese medicine suppository for treating premature ovarian failure of women and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] 1000g of Bletilla striata, 1000g of Angelica dahurica, and 1000g of peppermint are vaporized into crystals by distillation, then pulverized, passed through a 100-120 mesh sieve, and used as component 1 for later use; then 1000g of white peony root, 1000g of Mildew Spatholobus, 1000g of motherwort, and Fu 1000g, Comfrey 1000g, Patrinia 1000g, Ligustrum lucidum 1000g, Eclipta 1000g, Mulberry 1000g, Cuscuta 1000g, Epimedium 1000g, Paeonol 1000g, Pueraria 1000g, Sophora flavescens 1000g, Cnidium 1000g, Smilax tuckahoe 1000g, 1000g of Kochia scoparia, 1000g of dandelion, 1000g of eyebright, 1000g of jackfruit and chopped, soak it in a stainless steel bucket with a cover, add 70% ethanol liquid, the quality is 0.8-1 times of coarse particles, stir evenly, Keep it moist and airtight for more than 1 hour to fully expand; wrap the filter plate at the bottom of the percolation cylinder with a gauze bag and spread it flat, then mix and loosen the wet and expanded drug samples, then...

Embodiment 2

[0063] 1100g of Bletilla striata, 1200g of Angelica dahurica, and 1200g of peppermint are vaporized into crystals by distillation, then pulverized, passed through a 100-120 mesh sieve, and used as component 1 for later use; then 1200g of white peony root, 1200g of Mildew Spatholobus, 1200g of motherwort, and Fu 1200g, Comfrey 1200g, Patrinia 1200g, Ligustrum lucidum 1200g, Eclipta 1200g, Mulberry 1200g, Cuscuta 1200g, Epimedium 1200g, Paeonol 1200g, Pueraria 1200g, Sophora flavescens 1200g, Cnidium 1200g, Smilax tuckahoe 1200g, Kochia chinensis 1200g, dandelion 1200g, eyebright 1200g, jack 1200g chopped, put into ethanol and heat and reflux to extract 2 times, each time for 1-2 hours, combine the 2 extracts and let stand; Combine the extracts, concentrate under reduced pressure the filtrate with a relative density of 1.38 at 70°C, recover ethanol, adjust the specific gravity of the resulting filtrate to 1.60, and pass it into a spray dryer for spray drying. The compressed air p...

Embodiment 3

[0080] Embodiment 3: skin allergy test result

[0081] Use the suppository of the present invention to carry out induction and excitation contact tests, and treat the test mice after 24 hours and 48 hours, and there is no phenomenon such as erythema and edema in the skin, and there is no difference with the negative control group. The results show that the suppository has close to zero skin reaction intensity, that is, no skin allergy.

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PUM

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Abstract

The invention provides a traditional Chinese medicine suppository for treating premature ovarian failure of women. The suppository is prepared from the following raw materials in parts by weight: 10-20 parts of radix paeoniae alba, 10-20 parts of caulis spatholobi, 10-20 parts of herba leonuri, 10-20 parts of rhizoma cyperi, 10-20 parts of radices lithospermi, 10-20 parts of herba patriniae, 10-20 parts of glossy privet fruits, 10-20 parts of eclipta alba, 10-20 parts of mulberry, 10-20 parts of semen cuscutae, 10-20 parts of herba epimedii, 10-20 parts of cortex moutan, 10-20 parts of radix puerariae, 10-20 parts of radix sophorae flavescentis, 10-20 parts of fructus cnidii, 10-20 parts of rhizoma smilacis glabrae, 10-20 parts of bletilla striata, 10-20 parts of radix angelicae, 10-20 parts of fructus kochiae, 10-20 parts of dandelion, 10-20 parts of peppermint, 10-20 parts of eyebright and 10-20 parts of philippine flemingia roots. The medicinal materials are combined to achieve the effects of tonifying kidneys, nourishing yin, promoting blood circulation and regulating Chong-Ren. The traditional Chinese medicinal material for tonifying kidneys and regulating menstruation has the effects of delaying hypogonadotropic hypogonadism and promoting restoration of ovarian functions.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, in particular to a traditional Chinese medicine suppository for treating women with premature ovarian failure and a preparation method thereof. Background technique [0002] Premature ovarian failure (POF) refers to the phenomenon of amenorrhea before the age of 40 caused by ovarian failure. It is characterized by primary or secondary amenorrhea accompanied by elevated blood gonadotropin levels and decreased estrogen levels, accompanied by a series of low estrogen symptoms such as hot flashes, hyperhidrosis, facial flushing, and low libido. The average natural menopausal age of women is 50-52 years old, and there are differences in the distribution of menopausal age among races and regions, but the absolute value is not much different. Coulam et al. summarized the natural amenorrhea of ​​1858 women, and the incidence of POF was 1% for those younger than 40 years ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K36/90A61K9/02A61P15/08
CPCA61K36/71A61K9/0034A61K9/02A61K36/185A61K36/232A61K36/234A61K36/28A61K36/288A61K36/296A61K36/30A61K36/39A61K36/48A61K36/486A61K36/488A61K36/489A61K36/533A61K36/534A61K36/605A61K36/638A61K36/65A61K36/70A61K36/80A61K36/8905A61K36/896A61K36/898A61K36/90A61K47/10A61K47/14A61K47/44A61K2236/333A61K2236/51A61K2236/53A61K2300/00
Inventor 马佳
Owner 马佳
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