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Evaluation of carotid plaque using contrast enhanced ultrasonic imaging

A technology of contrast enhancement and ultrasound imaging, applied in image enhancement, ultrasound/sonic/infrasonic diagnosis, application, etc., can solve problems such as stroke and cerebrovascular obstruction

Active Publication Date: 2016-09-14
KONINKLJIJKE PHILIPS NV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the carotid artery provides blood supply to the brain, certain substances in the bloodstream of the carotid artery can cause blockage of the blood vessel in the brain and a potential risk of stroke

Method used

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  • Evaluation of carotid plaque using contrast enhanced ultrasonic imaging
  • Evaluation of carotid plaque using contrast enhanced ultrasonic imaging
  • Evaluation of carotid plaque using contrast enhanced ultrasonic imaging

Examples

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Embodiment Construction

[0015] In some embodiments, the present invention provides an ultrasound imaging system, for example, an ultrasound diagnostic imaging system, which is used to evaluate plaque by contrast-enhanced ultrasound. The system can include an ultrasound imaging probe with an array transducer that acquires a sequence of ultrasound images of the plaque during contrast delivery. In a specific embodiment, the system can be configured to include a processor, a memory, and other structures that can act as a time-intensity curve calculator, which forms an image for each point where a contrast agent is present in the plaque image. The time-intensity curve of the plaque, and the comparator, which identifies the perfused pixels in the plaque image. In one embodiment, the comparator is also operable to compare pixel intensity values ​​before and after the contrast agent reaches the patch. The system can also include a display that shows the degree of perfusion in the plaque. In a particular emb...

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Abstract

An ultrasound system and method are described for acquiring a sequence of ultrasound images of the carotid artery during the delivery of a contrast agent. Plaque in the images is identified and a time-intensity curve is calculated for pixels in the images. The intensity values before and after the arrival of contrast are compared to identify pixels or groups of pixels having perfusion. An anatomical image may be formed showing areas in an image of the plaque of the intensity and presence of perfusion, or the perfusion may be quantified by determining the percentage of pixels in the plaque image which exhibit perfusion. The extent and degree of perfusion is an indicator of the risk of plaque particulates in the blood stream which may lead to stroke-related symptoms.

Description

Technical field [0001] The present invention relates to an ultrasound diagnostic imaging system, and specifically relates to the use of contrast-enhanced ultrasound imaging to assess the risk of stroke. Background technique [0002] The development of plaque in the vasculature, especially atherosclerosis in the carotid artery, often occurs in many patients. Plaque can accumulate to a certain extent, in which partial and even complete blockage of blood vessels may occur. figure 1 A blood vessel 110 is shown in which the vessel wall 18 is partially cut away to show the internal lumen 16 in which plaque accumulation 24 is visible. Since the plaque 24 has filled most of the lumen at its thickest point, it has partially blocked blood flow through the blood vessel. Plaque not only restricts the delivery of fresh blood to tissues and organs downstream of the obstruction, but also traps blood clots in the narrowed lumen, blocking all blood flow. Another event of equal severity can be c...

Claims

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Application Information

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IPC IPC(8): G06T7/00
CPCG06T2207/10132G06T2207/10136G06T2207/30101G06T2207/30104G06T7/0016A61B8/06A61B8/4444A61B8/5223H04N23/683G06F18/22A61B8/4494A61B8/461A61B8/481G06T7/20G06T2207/20021
Inventor M·阿韦基乌D·克里斯托菲迪斯E·L·S·利恩
Owner KONINKLJIJKE PHILIPS NV
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