58 results about "Carotid artery plaque" patented technology

A system and method of obtaining and analyzing ultrasound images of a patient provides for the identification of specific tissue types in using the image data. A feature vector set of sub-regions of the region of interest is obtained, dimensionally reduced and evaluated using a heuristic to identify the tissue type. Where the tissue type is suitable for image standardization, the overall gray scale of the image is adjusted with respect to a predetermined gray scale for the identified tissue type. The image may be segmented and plaque regions identified and characterized. The characterized plaque and other parameters such as percent stenosis may be used to determine a risk score for the patient.

The invention belongs to the field of intersection of a computer technology and medical images, and in particular relates to a dividing method of plaque in the cross section direction of carotid artery blood vessel in an ultrasound image. The method specifically comprises the following steps of: selecting the current frame image; dividing to obtain profiles of internal and external membranes of the blood vessel; extracting the plaque and dividing the interested area; detecting an initial plaque external boundary: carrying out curve fitting on each column of pixel point gray value between the internal and external membrane profiles on a polar coordinate image obtained through conversion in the interested area, and detecting the pixel point with the minimum gray value and nearest to the external membrane profile as the initial plaque external boundary point; carrying out level set evolution to obtain the final plaque external boundary; and using the area between the final external boundary and the internal membrane profile as the plaque area. By adopting the dividing method of ultrasound carotid artery plaque, plaque can be accurately divided, the workload of doctors can be greatly reduced, and the plaque size and area calculated on the basis of the division result can help doctors analyze the lesion degree and treatment effect.

The invention discloses a method for intelligently segmenting the intracranial plaques and the carotid plaques of a magnetic resonance image, which comprises the following steps of S1, acquiring the blood vessel wall magnetic resonance image of a user; S2, preprocessing the blood vessel wall magnetic resonance image to obtain a preprocessed image; S3, segmenting a preset plaque region in the preprocessed image by a pre-trained convolutional neural network model; and S4, outputting a plaque tissue region segmentation image corresponding to the blood vessel wall magnetic resonance image. The method improves the accuracy of plaque segmentation of the blood vessel wall magnetic resonance image, thereby obtaining a high-precision segmentation image and contributing to improving diagnosis efficiency and improving the safety of an operation.

The present disclosure is directed to compounds, diagnostic agents, and related methods. In some cases, methods for treating patients are provided. More specifically, the disclosure provides compounds, diagnostic agents, and kits for detecting and / or imaging and / or monitoring elastin rich tissues. In addition, the disclosure provides methods of detecting and / or imaging and / or monitoring the presence of coronary plaque, carotid plaque, iliac / femoral plaque, aortic plaque, renal artery plaque, plaque of any arterial vessel, aneurism, vasculitis, other diseases of the arterial wall, and / or damage or structural changes in ligaments, uterus, lungs or skin, as indicated by changes in total vessel wall area, internal lumen size, and exterior arterial perimeter.

The invention provides a carotid plaque segmentation method and device based on artificial intelligence and a storage medium, and the method comprises the steps: obtaining an original mode image slice, and recognizing a bifurcated slice based on the original mode image slice; marking initial boundary points of the bifurcated slices, and interpolating the marked initial boundary points to create a continuous initial boundary; and refining the initial boundary through a distance regularization level set to obtain an intima boundary and an outer wall boundary of a carotid plaque blood vessel cavity, and obtaining the carotid plaque. According to the technical scheme provided by the invention, the carotid plaque is automatically segmented by using brand new 3DUS imaging based on a plaque segmentation integrated framework of 3DUS and deep learning, the accuracy of carotid plaque segmentation is improved, the plaque burden can be more comprehensively measured, and the recognition of the carotid plaque is more accurate.

The invention provides a carotid plaque identification method based on cross-modal prediction from CTA to MRA. The method comprises the following steps: a data collection step: paired carotid CTA andMRA image data are collected; plaque segmentation and model training: carotid artery lumens of CTA and MRA are positioned firstly, then carotid artery plaques are segmented, plaque area images of CTAand MRA are obtained, the plaque area images of CTA and MRA are sent to a pix2pix or cycle-GAN network to be trained, and a model obtained after preliminary training is obtained. According to the method, a complete and novel algorithm flow is designed, the carotid artery lumen and plaque on the CTA image are automatically segmented by using an improved deep learning Multiplan-net algorithm, and anoptimized adversarial generative network is designed on the basis to perform CTA data amplification, so that the segmentation precision is further improved.

The present disclosure is directed to compounds, diagnostic agents, and related methods. In some cases, methods for treating patients are provided. More specifically, the disclosure provides compounds, diagnostic agents, and kits for detecting and / or imaging and / or monitoring elastin rich tissues. In addition, the disclosure provides methods of detecting and / or imaging and / or monitoring the presence of coronary plaque, carotid plaque, iliac / femoral plaque, aortic plaque, renal artery plaque, plaque of any arterial vessel, aneurism, vasculitis, other diseases of the arterial wall, and / or damage or structural changes in ligaments, uterus, lungs or skin, as indicated by changes in total vessel wall area, internal lumen size, and exterior arterial perimeter.

The carotid artery plaque properties are quantitatively determined by a carotid artery echo whereby predicting incidence of cerebral infarction or myocardial infarct. A method includes obtaining, coloring, and displaying steps. In the obtaining step, the integrated amounts per unit time of echo signals corresponding to pixels of an echo image of carotid artery plaque are obtained. The signals are obtained when the image is obtained by an IBS method. In the coloring step, the relationship between ranges and colors is referenced. The available full range of the integrated amount is previously divided into the ranges. The colors are assigned to the ranges. The pixels are classified into the ranges in accordance with the integrated amounts corresponding to the pixels. The pixels of the image are colored in colors corresponding to the ranges of the pixels. In the displaying step, the colored echo image is displayed on a display portion 30.

The invention relates to a domestic and medical two-purpose sound recording and fetal heart sound listening stethoscope, and belongs to the field of medical apparatuses. A stethoscope head (1), a sound conduction tube, a three-way tube and a listening tube protecting port are mutually connected, so that a pipeline stethoscope is constituted; a microphone, an amplifier (2), a recording-playing module (3), a transmission module (4), a power supply and the like are arranged in the stethoscope head, so that an electronic stethoscope, which is capable of recording and playing sound, is formed to listen two different stethoscopic sound effects. People can identify sounds from left side and right side through two ears, but the known stethoscopes are operated in a mode of communicating left and right ears, and subsequently, a listening habit is changed and a hearing threshold is narrowed; with the application of the stethoscope which adopts a novel dual-sound-track circuit, the listening habit is recovered and the hearing threshold is widened, so as to bring about benefits for doctors in auscultation. In addition, known fetal heart rate instruments cannot output original heartbeat sound, while by virtue of the novel stethoscope, actual fetal heartbeat sound can be listened, and meanwhile, the sound can be recorded or played; and when the sound is recorded, a voice catalog can be additionally annotated by virtue of the microphone, so that functions of searching and tracing an electronic medical record can be developed. Moreover, a carotid artery plaque detection method is more convenient and rapider than the known stethoscopes.

The invention provides a magnetic resonance single-sequence multi-parameter quantitative imaging system for identifying carotid plaques, and belongs to the technical field of magnetic resonance quantitative imaging. The system comprises a carotid artery blood vessel coil, a magnetic resonance machine and a computer; and a working method of the system includes the following steps: compiling on a magnetic resonance imaging sequence programming platform in a computer to realize simultaneous quantitative imaging of SQUMA sequences of T1, T2 and T2 * values of carotid artery tube wall, importing the SQUMA sequences into a magnetic resonance machine, performing SQUMA sequence scanning on the neck of a subject by the magnetic resonance machine, and obtaining a corresponding carotid artery tube wall weighted image after scanning; and carrying out weighted fitting on the images to obtain T1mapping, T2mapping and T2 * mapping of the carotid artery wall of the subject. According to the system, quantitative images of T1, T2 and T2 * values of carotid artery tube wall plaques can be obtained at the same time through a single sequence, and technical support is provided for one-stop qualitative and quantitative evaluation of carotid artery vulnerable plaque characteristics.

Atherosclerosis can be viewed as a response to injury and it is not atherosclerosis per se that is serious but instead factors leading to rupture of atherosclerotic plaques. In the present invention we have identified such factors. A decreased binding of Annexing V to the endothelium was seen in patients with a history of atherothrombosis. The use of native Annexin V or an N-terminal fragment as an active component or a subfraction of immunoglobulins to manufacture a pharmaceutical composition is proposed to improve said binding. The use of Annexin V, N-terminal fragments or immunoglobulins to increase the Annexin V-binding to carotid plaque represents novel mechanism for preventing atherothrombosis.

The invention relates to the technical field of ultrasonic medical image processing, and particularly discloses a carotid plaque property judgment method, which comprises the following steps of obtaining an ultrasonic radiography video comprising a carotid plaque; identifying the ultrasound contrast video through a first neural network to obtain an angiography video, the angiography video comprising an image stream of an area where plaque blood vessels are located in the ultrasound contrast video; extracting the image features in the angiography video through a feature extraction model; and identifying the image features through a second neural network to obtain the property category of the plaque. The invention further discloses a storage medium and an ultrasonic device. According to thecarotid plaque property judgment method and device provided by the invention, the nature category of the plaque can be effectively identified, and the qualitative analysis of the carotid plaque is realized, so that an important basis is provided for the medical personnel to analyze and diagnose the carotid plaque.

The invention relates to traditional Chinese medicine decoction for treating carotid artery plaque, which is characterized by being prepared from the following traditional Chinese medicine raw materials: 10 g of gastrodia elata, 15 g of peach kernel, 30 g of astragalus membranaceus, 15 g of root of common peony, 15 g of lumbricus, 10 g of leech powder (taking after mixing with water), 10 g of wine-treated rhubarb, 15 g of carthamus tinctorius, 30 g of the root of red-rooted salvia, 15 g of the rhizome of chuanxiong, 50 g of the root of kudzu vine, 10 g of liquorice and 10 g of medicinal cyathula root. By means of dialectical compatibility of various raw materials, the traditional Chinese medicine decoction for treating carotid artery plaque disclosed by the invention has the effects of tonifying Qi, invigorating the circulation of blood and descending blood stasis and has obvious curative effect to patients suffering from carotid artery plaque, therefore, the traditional Chinese medicine decoction for treating carotid artery plaque is worthy of being popularized.

The invention relates to the technical field of medicine, and discloses a method for establishing a carotid arteriosclerosis and carotid plaque prediction model for common people. The method comprisesthe following steps: 1) selecting common people as modeling people; 2) collecting information; 3) grouping the modeling people, concretely, dividing the modeling people into a normal group and an abnormal group by taking the IMT maximum value of carotid arteries at the two sides as an evaluation index; 4) statistical modeling; and 5) prediction model evaluation. The method has the advantages thatthe prediction model is suitable for common physical examination crowds rather than high-risk crowds, the prediction efficiency of the prediction model is high, AUC reaches 0.88 or above, and the accuracy of the prediction model is 80% or above.

The invention provides a visual carotid plaque ultrasonic self-inspection instrument and relates to the technical field of medical automation equipment. The instrument specifically comprises at leastone ultrasonic probe for transmitting an ultrasonic signal to the carotid artery of a user and receiving and transmitting a reflected signal; a signal processing module is connected with the ultrasonic probe and used for providing ultrasonic signals for the ultrasonic probe and receiving and processing the reflected signal; a central processing module is connected with the signal processing moduleand a display module, and is used for carrying out image post-processing on the reflected signal to obtain a carotid artery ultrasonic image, carrying out carotid artery plaque identification on thecarotid artery ultrasonic image and outputting an identification result to the display module for real-time display; and a power supply is connected with the signal processing module and the central processing module and used for supplying power. The invention has the beneficial effects that a patient can use the instrument to scan and image plaques on carotid arteries by himself / herself, site limitation is avoided, the instrument is more convenient, examination images are transmitted in a wireless transmission mode, limitation is smaller, and self-examination of the patient is facilitated.

The invention provides a carotid plaque detection method and device based on a medical ultrasonic image, and the method comprises the steps: building a corresponding relation between a feature parameter in a carotid medical ultrasonic image of a patient and a new vessel perfusion mode in a carotid plaque through the self-learning capability of an artificial neural network; acquiring current feature parameter of the medical ultrasonic image corresponding to the current carotid artery of the patient; determining a new vessel perfusion mode in the current carotid plaque corresponding to the current feature parameter according to the corresponding relationship, specifically, determining a new vessel perfusion mode in the current carotid plaque corresponding to the feature parameter, comprisingdetermining the new vessel perfusion mode in the current carotid plaque corresponding to the feature parameter identical to the current feature parameter in the corresponding relation as the new vessel perfusion mode in the current carotid plaque. The ability of extracting effective features of the neural network is improved, the personnel cost required by detection is reduced, and the accuracy is high.

The invention discloses a traditional Chinese medicine for treating carotid plaque. The medicine is prepared from a red ginseng tail, pseudo-ginseng, an earthworm, a rhodiola root and safflower carthamus, and the weight ratio of the red ginseng tail to the pseudo-ginseng to the earthworm to the rhodiola root tothe safflower carthamus is 10:10:10:2:1; according to thetraditional Chinese medicine, the five medicines are combined, so that qi is enough to promote blood circulation, blood stasis is removed,veins are smooth, both manifestation and root cause of diseases are treated, and the carotidplaque is stabilized and removed.

The invention discloses traditional Chinese medicine for treating carotid plaque and belongs to the technical field of Chinese herbal medicine preparations. The traditional Chinese medicine is prepared from, by mass, 3 g of panax notoginseng powder, 15 g of prepared radix polygoni multiflori, 20 g of radix puerariae, 15 g of fructus crataegi and 5 g of hirudo. The preparation method includes the steps that the panax notoginseng powder, prepared radix polygoni multiflori, radix puerariae, fructus crataegi and hirudo are prepared into particles and mixed, and the traditional Chinese medicine is prepared. Pure natural Chinese herbal medicine is particularly selected for the rigorous formula, the traditional Chinese medicine has the effects of nourishing the liver and the kidney, eliminating stasis and softening hard masses, accelerating elimination of carotid plaque and reducing the risk of stroke episode of a patient. The traditional Chinese medicine lowers morbidity, the death rate and the disability rate, relieves pain of the patient, improves living quality of the patient and is safe, free of toxin or side effects after being taken for a long time and more convenient to take after being decocted. The traditional Chinese medicine is low in cost and can relieve the economic burden of the patient and household.

The invention belongs to the field of medical image recognition, and provides a carotid artery vulnerability grading method and system based on multi-modal imaging omics. The method comprises the following steps: acquiring at least one of a carotid artery ultrasound image and a nuclear magnetic resonance image; based on at least one of the carotid artery ultrasound image and the nuclear magnetic resonance image, adopting a carotid artery plaque grading model to obtain a vulnerability grade of the carotid artery plaque; the carotid plaque grading model comprises a multi-scale feature fusion network and an attention classification network; wherein the multi-scale feature fusion network is used for fusing extracted carotid ultrasound image sample features and carotid nuclear magnetic resonance image sample features based on carotid ultrasound image samples and carotid nuclear magnetic resonance image samples to obtain fusion features; the attention classification network is used for obtaining the vulnerability level of the carotid plaque based on the fusion features and the carotid ultrasound image sample features / carotid nuclear magnetic resonance image sample features.

A fluorescent imaging device for plaque monitoring enables fluorescent imaging in a normal environment other than a dark room, thereby preventing inconvenience for both a medical staff and a patient due to the dark room. Also, a carotid artery plaque can be monitored in greater detail and in a short time by means of generating and combining a fluorescent image and a photo-acoustic image.

The invention discloses a traditional Chinese medicine composition for treating carotid plaques. The traditional Chinese medicine composition comprises: officinal magnolia bark, amomum fruit, stir-fried rhizoma atractylodis, radix curcumae, lotus leaves, poria cocos, rhizoma chuanxiong, humulus scandens, caragana sinica rehd, caulis perllae, wrinkled gianthyssop herb stem and hiraute shiny bugleweed herb. The invention further discloses a method for preparing the traditional Chinese medicine composition for treating carotid plaques and application. According to the traditional Chinese medicinecomposition for treating carotid plaques, the various traditional Chinese medicines cooperate and act jointly according to the compatibility of 'monarch, minister, assistant and conductant', therebyacting on a focus, and exerting the therapeutic effect on treating carotid plaques. Clinical trials have shown that the traditional Chinese medicine composition has a good therapeutic effect on moderate and severe carotid plaques, and the total effective rate for carotid plaques is 86.6%, the carotid plaques do not recur easily after healing, and the traditional Chinese medicine composition has notoxic and side effects and has a wide range of application value.

The invention belongs to the field of intersection of a computer technology and medical images, and in particular relates to a dividing method of plaque in the cross section direction of carotid artery blood vessel in an ultrasound image. The method specifically comprises the following steps of: selecting the current frame image; dividing to obtain profiles of internal and external membranes of the blood vessel; extracting the plaque and dividing the interested area; detecting an initial plaque external boundary: carrying out curve fitting on each column of pixel point gray value between the internal and external membrane profiles on a polar coordinate image obtained through conversion in the interested area, and detecting the pixel point with the minimum gray value and nearest to the external membrane profile as the initial plaque external boundary point; carrying out level set evolution to obtain the final plaque external boundary; and using the area between the final external boundary and the internal membrane profile as the plaque area. By adopting the dividing method of ultrasound carotid artery plaque, plaque can be accurately divided, the workload of doctors can be greatly reduced, and the plaque size and area calculated on the basis of the division result can help doctors analyze the lesion degree and treatment effect.

The invention provides a plaster for treating carotid artery freckles and a preparation method thereof. The plaster for treating carotid artery freckles is prepared from the following components in percentage by weight: seaweed, scrophulariaceae, scorpion, chilopod, hemlock parsley, sea-tangle and borneol according to a certain weight proportion. The preparation method of the plaster comprises the following steps of: decocting the seaweed, the scorpion, the chilopod and the sea-tangle in water and filtering; then, depositing in ethanol to obtain filtrate, crushing the scrophulariaceae, the hemlock parsley and the borneol into fine powder; and mixing uniformly with the filtrate to obtain active ingredients of the plaster. The medicament provided by the invention has the efficacy of invigorating blood circulation, removing blood stasis, clearing dampness, resolving phlegm and lightening freckles. The plaster has a simple use process, low cost and wide application prospects and is convenient and safe to use.

An ultrasound system and method are described for acquiring a sequence of ultrasound images of the carotid artery during the delivery of a contrast agent. Plaque in the images is identified and a time-intensity curve is calculated for pixels in the images. The intensity values before and after the arrival of contrast are compared to identify pixels or groups of pixels having perfusion. An anatomical image may be formed showing areas in an image of the plaque of the intensity and presence of perfusion, or the perfusion may be quantified by determining the percentage of pixels in the plaque image which exhibit perfusion. The extent and degree of perfusion is an indicator of the risk of plaque particulates in the blood stream which may lead to stroke-related symptoms.

The present disclosure is directed to compounds, diagnostic agents, and related methods. In some cases, methods for treating patients are provided. More specifically, the disclosure provides compounds, diagnostic agents, and kits for detecting and / or imaging and / or monitoring elastin rich tissues. In addition, the disclosure provides methods of detecting and / or imaging and / or monitoring the presence of coronary plaque, carotid plaque, iliac / femoral plaque, aortic plaque, renal artery plaque, plaque of any arterial vessel, aneurism, vasculitis, other diseases of the arterial wall, and / or damage or structural changes in ligaments, uterus, lungs or skin, as indicated by changes in total vessel wall area, internal lumen size, and exterior arterial perimeter.