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Long-acting udder injection for treating dry mastitis in dairy cows and preparation method thereof

An udder injection and dry milk period technology, which can be applied in the directions of non-active ingredients medical preparations, medical preparations containing active ingredients, and pharmaceutical formulas, etc. Pathogen resistance and other problems, to achieve the effect of promoting damaged tissue repair and immune regulation, reducing antibiotic residues, and lasting efficacy

Active Publication Date: 2019-02-12
QILU ANIMAL HEALTH PROD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] However, the single use of antibiotics can easily induce drug resistance of pathogenic bacteria and easily lead to antibiotic residues, which will affect the treatment effect of dairy cow mastitis and the quality of dairy products, and have adverse effects on the development of the dairy industry and human health.

Method used

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  • Long-acting udder injection for treating dry mastitis in dairy cows and preparation method thereof
  • Long-acting udder injection for treating dry mastitis in dairy cows and preparation method thereof
  • Long-acting udder injection for treating dry mastitis in dairy cows and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Long-acting udder injection for the treatment of dry mastitis in dairy cows, the composition per hectogram is as follows:

[0042]

[0043] The preparation method is as follows:

[0044](1) adding the aluminum distearate of the prescribed amount into part of the liquid paraffin, heating at 145° C. and stirring continuously, so that the slow-release agent is fully dissolved and stirred evenly, and the temperature is lowered to obtain a slow-release solution;

[0045] (2) dissolving the glyceryl monostearate of prescription quantity and the butylated hydroxytoluene (BHT) of prescription quantity in the liquid paraffin of remainder, stir and disperse evenly, make emulsion;

[0046] (3) Mix the sustained-release liquid prepared in step (1) with the emulsion prepared in step (2), and after stirring evenly, add the prescribed amount of micronized cefuroxime and tanshinone extract to the feed liquid , 50Hz ultrasound and emulsification with a high-speed shear emulsifier to...

Embodiment 2

[0048] Long-acting udder injection for the treatment of dry mastitis in dairy cows, the composition per hectogram is as follows:

[0049]

[0050] The preparation method is the same as in Example 1.

Embodiment 3

[0052] Long-acting udder injection for the treatment of dry mastitis in dairy cows, the composition per hectogram is as follows:

[0053]

[0054] The preparation method is the same as in Example 1.

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Abstract

The invention relates to a long-acting breast injection agent for treating cow mastitis in dry period and a preparation method of the long-acting breast injection agent. The long-acting breast injection agent is prepared from the following raw materials: cefalonium, a tanshinone extract, a slow-release agent, an emulsifier, an antioxidant and an oily solvent. The breast injection agent provided by the invention is mainly used for preventing and treating clinical mastitis and subclinical mastitis caused by staphylococcus aureus, streptococcus, Escherichia coli and the like, has the characteristics of long-lasting property, high stability and high efficiency, and has good clinical application value and market prospects.

Description

technical field [0001] The invention relates to a long-acting udder injection for treating dry mastitis in dairy cows and a preparation method thereof, in particular to a long-acting udder injection containing cefuroxime and a preparation method thereof, belonging to the technical field of veterinary medicine preparations. Background technique [0002] Cow mastitis is a common and frequently occurring disease of dairy cows. It is difficult to prevent and treat, and the cost of treatment is high. [0003] Cow mastitis is divided into two types: invisible mastitis and clinical mastitis. It is caused by pathogenic microorganisms invading mammary gland tissue. There are many kinds of pathogenic microorganisms. According to statistics, there are more than 130 kinds of pathogenic bacteria, and the most common clinical pathogenic bacteria are more than 20. species, mainly Staphylococcus aureus, Streptococcus and Escherichia coli. Clinical mastitis can cause breast redness, swellin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/58A61K31/546A61K9/107A61K47/12A61P31/04A61P15/14
CPCA61K9/0002A61K9/0041A61K9/107A61K31/546A61K31/58A61K47/12A61K2300/00
Inventor 王海挺田振平梁秀婷朱祈明孟双双韩文王甜孔梅吴连勇
Owner QILU ANIMAL HEALTH PROD
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