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40results about How to "Has sustained release properties" patented technology

Long-acting slow-release microcapsule food antistaling agent and preparation method thereof

The invention provides a long-acting slow-release microcapsule food antistaling agent and a preparation method thereof. The antistaling agent comprises natural antiseptic patchouli oil as the core material and natural polymer chitosan and gelatin as the wall materials. The antistaling agent is prepared by complex coacervation, comprising the following steps: preparing a chitosan-acetic acid solution and a gelatin solution, uniformly mixing 0.5-3.0wt% of the chitosan-acetic acid solution and 1.0-3.0wt% of the gelatin solution, then adding a certain amount of patchouli oil and emulsifier, emulsifying for a certain time under stirring, and then regulating the pH value of the system to a proper value, after completing the complex coacervation reaction, adding 10wt% of vanillin-alcohol solution to conduct curing crosslinking reaction for a certain time, and finally conducting pumping filtration, washing and freeze drying to obtain the powdery microcapsule food antistaling agent. The antistaling agent has the particle size of 1-10 mum, good sphericity and dispersibility, the embedding rate of 85-92%, the drug-loading rate of 30-40%, and significant slow release effect, and has no toxicity, safety, and long acting and lasting fresh-keeping and anticorrosion effects. The preparation method has the advantages of simple and easiness in operation, good repeatability, low requirement for devices, no toxicity and nature of raw materials, wide obtainment of sources, and low production cost, and is suitable for industrial production.
Owner:AGRI PRODS PROCESSING RES INST CHINESE ACAD OF TROPICAL AGRI SCI

Arsenic-trioxide-carrying pH-responsive mesoporous silica nanoparticle and preparation method thereof

The invention discloses an arsenic-trioxide-carrying pH-responsive mesoporous silica nanoparticle and a preparation method thereof. The preparation method of the arsenic-trioxide-carrying pH-responsive mesoporous silica nanoparticle mainly comprises the following steps: preparing amino modified mesoporous silica by adopting a coprecipitation method, and loading conjugate acid and base ATO and PAA through electrostatic adsorption for preparing PAA-ATO-MSNs. The prepared PAA-ATO-MSNs are circular or quasi-circular in appearance under a transmission electron microscope, average particle size is (158.6+ / -1.32)nm, Zeta potential is (-28.40+ / -0.34)mV, and encapsulation efficiency and drug loading rate are (40.95+ / -3.21)% and (11.42+ / -1.75)% respectively; in vitro drug release is pH-responsive, and accumulated release amount is increased along with reduction of pH value; pharmacokinetic study shows that compared with ATO-Sol and ATO-MSNs, t1 / 2beta of PAA-ATO-MSNs is obviously prolonged and AUC is obviously increased (P is less than 0.01); and PAA-ATO-MSNs in vitro drug release has obvious pH responsiveness and sustained release property, in vivo pharmacokinetic behaviours of a rat can be obviously improved, and the arsenic-trioxide-carrying pH-responsive mesoporous silica nanoparticle carrier can serve as an ATO tumour-targeted drug delivery system and has a good application prospect.
Owner:ZHEJIANG CHINESE MEDICAL UNIVERSITY

Corrosion inhibitor microcapsules based on graphene rolls and preparation method of corrosion inhibitor microcapsules

The invention discloses corrosion inhibitor microcapsules based on graphene rolls. The microcapsules adopt graphene as a capsule wall material and adopt an organic corrosion inhibitor as a core material. The invention further discloses a preparation method of the microcapsules. After a water solution of the organic corrosion inhibitor is blended with graphene oxide, the mixture is subjected to hydrothermal treatment at 80-200 DEG C for 8-24 h, the corrosion inhibitor is coated with the microcapsules while graphene is rolled under the hydrothermal condition, the core material coating quality is high, and the slow release characteristic of the corrosion inhibitor is good. The method adopts a simple coating process, is convenient to operate and low in preparation cost, and does not need additional aids.
Owner:QINGDAO AGRI UNIV

Super low free radical cigarette

The cigarette with super low free radical content features its delayed released plant polyphenol microcapsule content of 0.02-0.6 wt% of shredded tobacco. The plant polyphenol microcapsule is first dissolved in water, alcohol, mixture of water and alcohol or water solution of propylene glycol and the solution is then sprayed to shredded tobacco. The delayed released plant polyphenol microcapsule may be catechin microcapsule, gallic acid microcapsule as degraded product of tannin or grape polyphenol microcapsule. The added plant polyphenol has stability raised by 9-12 times, extraneous antioxidant performance raised by 5-6 times and intracorporal antioxidant performance raised by about 10 times. Its effective component may be absorbed by oral cavity and respiratory system to eliminate free radical in body while meeting the need of smokers.
Owner:CHANGDE CIGARETTE FACTORY

Technological method for producing composite probiotic two-layer microcapsule by virtue of double-emulsification method-spray drying

PendingCN108902983AOptimizing the composition mass to volume ratioFlat surfaceFood shapingProduction rateControl release
The invention relates to a technological method for producing a composite probiotic two-layer microcapsule by virtue of a double-emulsification method-spray drying which is suitable for various activeprobiotic composite micro-ecological preparations, which belongs to the technical field of food microorganisms. The two-layer microcapsule prepared by adopting the double-emulsificaiton-spray dryingmethod is high in probiotic embedding efficiency, good variable bacteria stability, complete in surface and is in an approximate spherical shape; and moreover, the embedded component is released afterpassing by two interfaces, so that the burst release phenomenon can be overcome, the release time can be prolonged, and the controlled-release performance is good. The production device is simple, the operation is convenient, the labor protection is facilitated, the process period is short, the productivity is high, the finished product has good acid tolerance and cholate resisting capability, the source of raw materials is wide, the price is low, the industrialized continuous mass production can be realized, and a foundation can be laid for the industrialized production of the probiotic products.
Owner:SHENZHEN POLYTECHNIC

Preparation method of slow release type fruit and vegetable sterilizing fresh keeping agent

The invention provides a preparation method of a slow release type fruit and vegetable sterilizing fresh keeping agent. Raw materials of the slow release type fruit and vegetable sterilizing fresh keeping agent comprise distilled water, beer dry yeast, majoram essential oil and anhydrous alcohol. The preparation method comprises the following steps of firstly adding the beer dry yeast to a given amount of the distilled water for activation, then adding an appropriate amount of the majoram essential oil, performing stirring for a definite time, enabling the majoram essential oil to enter the inner parts of yeast cells through permeation and diffusion effects to form microcapsules, then performing centrifuging, performing vacuum filtration on sediments, washing filter residues with anhydrousalcohol, washing away the majoram essential oil which is not embedded, and performing vacuum freeze drying on filter residues so as to obtain the slow release type fruit and vegetable sterilizing fresh keeping agent capable of slowly releasing the majoram essential oil. The slow release type fruit and vegetable sterilizing fresh keeping agent can be encapsulated with ventilated non-woven fabric bags when being used, the majoram essential oil which is slowly released can restrain propagation and growth of bacterial colonies, can reduce rot of fruits and vegetables and achieve the purpose of keeping fresh through destroying the permeability of cell membranes of pathogenic bacteria.
Owner:SHANDONG UNIV OF TECH

Controlled release halloysite-loaded 2-mercaptobenzothiazole and phenyltriazole composite corrosion inhibitor and preparation method thereof

The invention discloses a controlled release halloysite-loaded 2-mercaptobenzothiazole and phenyltriazole composite corrosion inhibitor and a preparation method of the controlled release halloysite-loaded 2-mercaptobenzothiazole and phenyltriazole composite corrosion inhibitor. According to a nano container effect of halloysite and the synergistic effect of 2-mercaptobenzothiazole and phenyltriazole, the 2-mercaptobenzothiazole and the phenyltriazole are sequentially loaded into halloysite through a negative pressure method, and an insoluble Cu-BTA composite is formed at a port of the halloysite by the interaction of BTA and Cu ions on an orifice to control the release speed of the 2-mercaptobenzothiazole and the phenyltriazole. By means of the controlled release and composite corrosion inhibiting behaviors of the corrosion inhibitor, the corrosion resistance and service life of a seawater circulation cooling system are increased.
Owner:TIANJIN UNIV

Docetaxel nanometer lipid injection, preparation method and purpose thereof

The present invention relates to a docetaxel nanometer lipid injection. The invention also relates to a method for preparing the docetaxel nanometer lipid injection. The invention further relates to the application of the docetaxel nanometer lipid injection for preparing medicament for treating a tumor. The nanometer preparation of the invention is capable of prolonging the medicament action time, conveying the medicament with a target, reducing the administration dose under the precondition of ensuring the medicament action, alleviating or avoiding medicament toxin and side effects, improving the medicament action stability, and being benefited for the medicament storage, thus it is capable of implementing the development of the medicament which has advantages in the aspects of a high yield, automatization, large scale, low cost, convenient carry and storage, small dose and low side-effect.
Owner:HAIKOU PHARMA FACTORY +1

Preparation method of fertilizer with functions of reducing content of heavy metal ions and achieving sustained release

ActiveCN108586114ANot easy to loseEnhance the ability to continuously remove heavy metal ions in soilMagnesium fertilisersOrganic fertilisersSoil treatmentWater insoluble
The invention relates to a sustained release fertilizer capable of reducing the content of heavy metal ions in soil and a preparation method thereof. By adopting sodium sulfide, polyvinyl alcohol, aluminum nitrate nonahydrate, magnesium nitrate hexahydrate, lignin and urea as reaction raw materials, the sustained release fertilizer with sulfur-containing hydrotalcite and lignin as carriers is prepared through a reaction. Sulfur ions in the sustained release fertilizer and the heavy metal ions can generate a water-insoluble sulfide precipitate, the effect of reducing the content of the migration-state heavy metal ions in the soil is achieved, and meanwhile a compound composed of sulfur-containing hydrotalcite and lignin has the sustained release function on urea. The dual-functional fertilizer can reduce environmental pollution caused by excessive heavy metal ions in the soil and reduce the cost of soil treatment without affecting normal agricultural production.
Owner:NANJING FORESTRY UNIV

Preparation method of oregano essential oil nano-microcapsules

The invention provides a preparation method of oregano essential oil nano-microcapsules. The preparation method of the oregano essential oil nano-microcapsules mainly comprises the following steps: firstly, correspondingly dissolving gelatin and Arabic gum; then uniformly mixing; adding oregano essential oil into a mixed solution and homogenizing; then adjusting the pH (potential of Hydrogen) to be acidic by utilizing 10 percent glacial acetic acid and continually stirring for certain time; then taking out; cooling to about 10 DEG C in an ice-water bath; adjusting the pH to be 6.0 by utilizing10 percent sodium hydroxide; adding glutamine transaminase; continually stirring and curing; standing and filtering to obtain a nano-microcapsule solution; pre-cooling the nano-microcapsule solutionat -20 DEG C for 24h; and then freezing and drying under a pressure vacuum condition of 1Pa for not less than 24h to obtain solid-state nano-microcapsules. According to the preparation method providedby the invention, the oregano essential oil can be slowly released and the acting time of the oregano essential oil is prolonged.
Owner:SHANDONG UNIV OF TECH

Slow-released fertilizer capable of decreasing content of heavy metal ions in soil and preparation method thereof

ActiveCN105418337ANot easy to loseEnhance the ability to continuously remove heavy metal ions in soilMagnesium fertilisersOrganic fertilisersHydration reactionSoil treatment
The invention relates to a slow-released fertilizer capable of decreasing the content of heavy metal ions in soil and a preparation method thereof. The slow-released fertilizer is prepared through a reaction by taking sodium sulfide, polyvinyl alcohol, aluminum nitrate nonahydrate, magnesium nitrate hexahydrate, lignin and urea as the reaction raw materials and taking sulfurated hydrotalcite and lignin as carriers. Sulfur ions in the slow-released fertilizer and the heavy metal ions can form water-insoluble sulfide precipitation, the effect of decreasing the content of migrated heavy metal ions in the soil is achieved, and meanwhile a compound formed by the sulfurated hydrotalcite and the lignin has a slow-release function on the urea. The bi-functional fertilizer does not affect normal agricultural production and can reduce environmental pollution caused by the excessive heavy metal ions in the soil, and the cost of soil treatment is reduced.
Owner:湖南斯多瑞农业发展有限公司

Preparation method of fishy-smell-removed bighead carp slices based on slow release of fresh ginger essential oil microemulsion

The invention discloses a preparation method of fishy-smell-removed bighead carp slices based on slow release of fresh ginger essential oil microemulsion. The preparation method comprises the following steps of preparing the fresh ginger essential oil microemulsion by using the raw materials of fresh ginger essential oil, ethanol, nisin, tea polyphenols, an emulsifying agent and the like; pretreating bighead carps to obtain bighead carp slices of which the thickness is 4-6mm; soaking the treated bighead carp slices in the fresh ginger essential oil microemulsion, and then performing draining;and performing vacuum packing on the bighead carp slices obtained in the step C. The fishy-smell-removed bighead carp slices prepared by the method disclosed by the invention have the characteristicsthat the effect of removing fishy smell is good, and the duration is long.
Owner:杭州邦沃森生物科技有限公司

Material capable of controlling slow release of fertilizer

The invention provides a material capable of controlling the slow release of a fertilizer. The composite material is synthesized by the following steps of: firstly, conducting hydro-thermal synthesis into carbon sphere materials by utilizing organic carbon materials with different concentrations; drying the carbon materials, evenly suspending into deionized water, conducting ultrasonic dispersion together with L-aspartic acid, a trace crosslinking agent and a catalyst under the condition of nitrogen protection, and synthesizing into an intermediate at a high temperature, flushing the intermediate to be neutral respectively with methanol and water; conducting crushing, basic hydrolysis and neutralization to the intermediate to be neutral, precipitating and filtering the neutralized hydrolysate into a sodium chloride-methanol saturated solution, flushing with methanol, and drying to obtain a polyaspartic acid-modified carbon sphere material. The material can be widely used in the field of fertilizers, and has an excellent fertilizer slow release effect.
Owner:NANJING TECH UNIV

Method for preparing lily polysaccharide microcapsule

The invention provides a method for preparing a lily polysaccharide microcapsule. The method for preparing the lily polysaccharide microcapsule comprises the following main steps: first dissolving gelatin and arabic gum separately, then performing uniform mixing, adding lily polysaccharide into the mixed solution, performing high-speed dispersion for 3 min under 100 r / min, adjusting pH to be acidity with 10% glacial acetic acid and then continuing to stir for a certain period of time and then performing taking-out, performing cooling to about 10 DEG C in an ice-water bath, adjusting pH to 6.0with 10% sodium hydroxide, adding transglutaminase (TGase), continuing to stir and solidify, performing standing and vacuum filtration to obtain a wet capsule product, spreading the microcapsule wet capsule flat in a petri dish, performing pre-cooling at -20 DEG C for 24 h, and then performing freeze-drying under 1 Pa pressure vacuum conditions for a time not less than 24 h to obtain the solid microcapsule. The microcapsule can slowly release the lily polysaccharide, prolongs the action time, improves the utilization efficiency of the lily polysaccharide, and realizes the wider application ofthe lily polysaccharide in the fields of food and medicine.
Owner:SHANDONG UNIV OF TECH

Bulleyaconitine A lipidosome freeze-dried powder injection and preparation method thereof

The invention provides a bulleyaconitine A lipidosome freeze-dried powder injection and a preparation method thereof. The injection mainly comprises the following compositions by weight ratio: bulleyaconitine A:phospholipid:cholesterol:freeze-dry protecting agent=1:1-60:1-10:1-360. The prepared freeze-dried powder injection with encapsulation rate of between 75 and 90 percent not only can obviously improve storage stability, but also can lead the bulleyaconitine A lipidosome freeze-dried powder to be re-dissolved after injection water is added. The prepared bulleyaconitine A lipidosome freeze-dried powder injection has light or non irritation in clinic application compared with the prior bulleyaconitine A injection, and has slow release property compared with common preparation.
Owner:KPC PHARM INC

Slow release fertilizer used for potted leafy plants and preparation method thereof

InactiveCN105272690ALow costEfficient use ofFertilizer mixturesNormal growthDeep ocean minerals
The invention discloses slow release fertilizer used for potted leafy plants and a preparation method thereof. The slow release fertilizer is prepared from urea formaldehyde rubber powder, copper sulfate, ferrous chloride, borax, magnesium chloride, zinc sulphate heptahydrate, potassium humate, animal waste, traditional Chinese medicine residues and ash, mushroom residues, animal bones, knar clay and the like. The prepared slow release fertilizer is low in cost and easy and convenient to apply; mineral substances and microelements, such as nitrogen phosphorus and potassium, required for growth of leafy plants are met through various added inorganic substances, and normal growth of leafy plants is ensured; nutrient elements required for plants can be provided through added organic substances such as potassium humate, animal waste and deep sea mineral salt; by matching and retting the raw materials , plants can be dark green and bright in leaf color in the growth process, and the ornamental value of plants is greatly improved; slow release components such as urea formaldehyde rubber powder and ethylene oxide / propylene epoxide copolymers and hydroxypropyl xanthan gum are added, and therefore the prepared fertilizer can have the slow release characteristic, the fertilizer efficiency can be lasting, and growth requirements of potted leafy plants can be met through one-time fertilizer application.
Owner:BEIJING UNIV OF AGRI

Slow-release fertilizer capable of reducing heavy metal ion content in soil and preparation method thereof

ActiveCN105418337BEnhance the ability to continuously remove heavy metal ions in soilNot easy to loseMagnesium fertilisersOrganic fertilisersPolyvinyl alcoholTalc
The invention relates to a slow-release fertilizer capable of reducing the content of heavy metal ions in soil and a preparation method thereof. The slow-release fertilizer adopts sodium sulfide, polyvinyl alcohol, aluminum nitrate nonahydrate, magnesium nitrate hexahydrate, lignin and urea as reaction raw materials , a slow-release fertilizer with sulfur-containing hydrotalcite and lignin as carriers was prepared. The sulfur ions in the slow-release fertilizer can form water-insoluble sulfide precipitation with heavy metal ions, so as to reduce the content of migratory heavy metal ions in the soil. release function. The dual-function fertilizer can reduce the environmental pollution caused by excessive heavy metal ions in the soil and reduce the cost of soil treatment while not affecting normal agricultural production.
Owner:湖南斯多瑞农业发展有限公司

Entecavir-loaded mesoporous silica nanoparticle and preparation method thereof

The invention belongs to the technical field of medicines, and relates to an entecavir-loaded mesoporous silica nanoparticle and a preparation method thereof. The entecavir-loaded mesoporous silica nanoparticle provided by the invention contains entecavir and mesoporous silica nanoparticle. According to the entecavir-loaded mesoporous silica nanoparticle provided by the invention, the bioavailability of the entecavir is improved; the entecavir-loaded mesoporous silica nanoparticle can be slowly released in a body; and according to the preparation method provided by the invention, the drug loading capacity is greatly improved.
Owner:CHIA TAI TIANQING PHARMA GRP CO LTD

Long-acting breast injection agent for treating cow mastitis in dry period and preparation method of long-acting breast injection agent

The invention relates to a long-acting breast injection agent for treating cow mastitis in dry period and a preparation method of the long-acting breast injection agent. The long-acting breast injection agent is prepared from the following raw materials: cefalonium, a tanshinone extract, a slow-release agent, an emulsifier, an antioxidant and an oily solvent. The breast injection agent provided by the invention is mainly used for preventing and treating clinical mastitis and subclinical mastitis caused by staphylococcus aureus, streptococcus, Escherichia coli and the like, has the characteristics of long-lasting property, high stability and high efficiency, and has good clinical application value and market prospects.
Owner:QILU ANIMAL HEALTH PROD +1

Preparation method of amomum villosum essential oil microcapsule

The invention provides a preparation method of an amomum villosum essential oil microcapsule. The preparation method mainly comprises the following steps: by taking amomum villosum essential oil as a core material and one or more of an inulin-lysozyme aqueous solution, an inulin-chitosan aqueous solution, a pectin-lysozyme aqueous solution and a pectin-chitosan aqueous solution as wall materials, adjusting the pH value of a system to 3-10 according to a mass ratio of the amomum villosum essential oil to the nanoparticle aqueous solution of 2: 1-1: 2, stirring at a high speed of 800-1600 r / min to obtain a pickering emulsion product, carrying out ultrasonic dispersion for 30-60 minutes under the power of 200W, and then carrying out spray drying to obtain the amomum villosum essential oil microcapsule. The amomum villosum essential oil microcapsule prepared by the method not only can protect the activity of the amomum villosum essential oil and realize slow release of the amomum villosum essential oil, but also has biological activity of inducing apoptosis of human hepatoma cells HepG2, and can realize wider application of the amomum villosum essential oil in the fields of food, health care products and medicines.
Owner:MINNAN NORMAL UNIV +1

Controllable release halloysite supported molybdate and benzotriazole composite corrosion inhibitor and preparation method thereof

InactiveCN110607086AIncrease the effect of slow releaseHas sustained release propertiesAnti-corrosive paintsHalloysiteControlled release
The invention discloses a controllable release halloysite supported molybdate and benzotriazole composite corrosion inhibitor and a preparation method thereof. According to the nano container effect of halloysite and the synergistic effect of MoO4<2-> and BTA; molybdate and BTA are supported into halloysite in sequence through a negative pressure method; meanwhile, an insoluble Cu-BTA compound isformed at the port of the HNTs by utilizing the interaction of BTA and Cu ions at the pipe orifice to slow down the release speed of MoO4 <2-> and BTA in the pipe, so that the corrosion resistance ofthe marine anticorrosive paint is improved and the service life of the marine anticorrosive paint is prolonged through the controlled release and composite corrosion inhibition behaviors of the corrosion inhibitor.
Owner:TIANJIN UNIV

Floating microorganism adhesive porous hydrogel and preparation method thereof

The invention discloses a preparation method of a floating bioadhesive porous hydrogel. The porous hydrogel is a non-effervescent granule and is prepared by adopting an orifice-coagulating bath method, wherein the method is simple, and reaction conditions are mild. A micropill is prepared from drugs and a carrier, wherein the carrier is a natural high molecular polysaccharide substance, has biocompatibility and bioadhesion, is sensitive to the pH value and does not have toxic side effect. The preparation method of the micropill comprises the following steps of: firstly, adding water-insolubledrugs into a solution containing surfactants, and stirring or ultrasonically dispersing uniformly; stirring at a higher speed; adding polysaccharides for dissolving to form uniform viscous mixture; then adding the mixture into a chitosan coagulating bath containing calcium chloride in a form of droplets for cross-linking curing; washing with water; and drying to obtain the micropill. The preparedmicropill has good floatability, bioadhesion and sustained release property in the stomach, and has bioadhesion and pulsed sustained release property in the intestinal tract.
Owner:SHENYANG PHARMA UNIVERSITY

Premixed feed capable of improving egg production of summer laying hens

The invention discloses premixed feed capable of improving the egg production of summer laying hens, and belongs to the technical field of laying hen breeding. The feed can realize the effect of innovatively introducing a special additive to cope with the heat stress response of the summer laying hens by improving the formula of premixed feed, and the feed uses an anti-heat stress sustained-release pill as a main raw material and a plurality of additives as auxiliary materials, uses the heat-clearing toxicity-removing properties to cool blood reduce temperature when the laying hens are fed with the feed while fully providing nutrients required by the laying hens, synchronously supplement a calcium source and vitamin C to maintain the continuous synthesis of protein and inhibit rising of body temperature; in addition, the anti-heat stress sustained-release pill has certain sustained-release properties, can be used during eating and digestion and has a long-time continuous effect, can avoid the physical discomfort of the laying hens caused by excessive cooling due to one-time release. The feed can greatly improve the egg production of the summer laying hens, and improve the survivalrate and egg quality of the laying hens.
Owner:南通和美华科技饲料有限公司

Long-acting udder injection for treating dry mastitis in dairy cows and preparation method thereof

The invention relates to a long-acting breast injection agent for treating cow mastitis in dry period and a preparation method of the long-acting breast injection agent. The long-acting breast injection agent is prepared from the following raw materials: cefalonium, a tanshinone extract, a slow-release agent, an emulsifier, an antioxidant and an oily solvent. The breast injection agent provided by the invention is mainly used for preventing and treating clinical mastitis and subclinical mastitis caused by staphylococcus aureus, streptococcus, Escherichia coli and the like, has the characteristics of long-lasting property, high stability and high efficiency, and has good clinical application value and market prospects.
Owner:QILU ANIMAL HEALTH PROD +1

Anti-pollution method of spray bottle

The invention provides an anti-pollution method for a spray bottle. The clathrate containing essential oil is prepared, and then a medicine box for accommodating the clathrate is arranged on the inner wall of the bottle cap of the spray bottle, and the clathrate is placed in the medicine box. The essential oil is volatilized inside the spray bottle, wherein the clathrate is formed by mixing the essential oil with an inclusion agent, or is formed by loading the essential oil on a carrier. The anti-pollution method provided by the present invention uses essential oils derived from natural plants instead of common synthetic antibacterial agents, which has less toxic and side effects and better safety; making essential oils into clathrates with slow-release properties can prolong their use efficacy, Make it work stably for a long time; put the essential oil inclusion compound in the bottle cap of the spray bottle, which can avoid the influence with the substances in the bottle, and can form an antibacterial environment in the spray bottle, thereby solving the problem of bacterial contamination, especially It is the problem of bacterial contamination at the nozzle; the method of the invention has a wide range of sources of raw materials, a simple and convenient production method, and has great potential for large-scale application.
Owner:上海弼诺医疗器械有限公司

Long-acting slow-release microcapsule food antistaling agent and preparation method thereof

The invention provides a long-acting slow-release microcapsule food antistaling agent and a preparation method thereof. The antistaling agent comprises natural antiseptic patchouli oil as the core material and natural polymer chitosan and gelatin as the wall materials. The antistaling agent is prepared by complex coacervation, comprising the following steps: preparing a chitosan-acetic acid solution and a gelatin solution, uniformly mixing 0.5-3.0wt% of the chitosan-acetic acid solution and 1.0-3.0wt% of the gelatin solution, then adding a certain amount of patchouli oil and emulsifier, emulsifying for a certain time under stirring, and then regulating the pH value of the system to a proper value, after completing the complex coacervation reaction, adding 10wt% of vanillin-alcohol solution to conduct curing crosslinking reaction for a certain time, and finally conducting pumping filtration, washing and freeze drying to obtain the powdery microcapsule food antistaling agent. The antistaling agent has the particle size of 1-10 mum, good sphericity and dispersibility, the embedding rate of 85-92%, the drug-loading rate of 30-40%, and significant slow release effect, and has no toxicity, safety, and long acting and lasting fresh-keeping and anticorrosion effects. The preparation method has the advantages of simple and easiness in operation, good repeatability, low requirement for devices, no toxicity and nature of raw materials, wide obtainment of sources, and low production cost, and is suitable for industrial production.
Owner:AGRI PRODS PROCESSING RES INST CHINESE ACAD OF TROPICAL AGRI SCI

PAMAM-TPGS as well as preparation method and application thereof

The invention provides a dendritic polymer-vitamin E succinate polyethylene glycol 1000 (PAMAM-TPGS), a preparation method thereof and an application of the dendritic polymer-vitamin E succinate polyethylene glycol 1000 (PAMAM-TPGS) as a drug carrier in preparation of a drug preparation. The dendritic polymer-vitamin E succinate polyethylene glycol 1000 nanoparticles prepared by a micro-channel method, a film dispersion method and an emulsion solvent evaporation method respectively have the characteristics of easiness in industrialization, high drug loading capacity and stable system, can obviously improve the solubility of a model drug in water and realize controllable release, have obvious pharmacological activity, and can be used for preparing a drug carrier for the drug. The device is suitable for various administration modes such as intravenous injection.
Owner:ZHEJIANG UNIV OF TECH

Enhanced denitrification method and device

The invention discloses an enhanced denitrification method and device, and belongs to the technical field of wastewater treatment. The enhanced denitrification device comprises an anoxic tank, an aerobic tank and a carbon source multiplier which are connected in sequence, and the output end of the carbon source multiplier is connected with the anoxic tank; a plurality of membrane contactors are fixed in the carbon source multiplier, the membrane contactors are of hollow structures, and gaps exist between the membrane contactors and a shell of the carbon source multiplier; when the device disclosed by the invention is used for denitrification, a macromolecular carbon source can be added in the denitrification process, the macromolecular carbon source is hydrolyzed into volatile fatty acid by utilizing hydrolysis zymophyte existing in a gap between the carbon source multiplier and the membrane contactor, and then the volatile fatty acid is diffused and permeated into a hollow structure of the membrane contactor through the membrane; as a small molecular carbon source which can be efficiently utilized by denitrifying bacteria, the denitrification process is promoted.
Owner:SUN YAT SEN UNIV

Method for preparing solid organic carbon fertilizer with livestock and poultry breeding waste as raw material

InactiveCN105315017BEnsuring rich nutritionEliminate serious environmental problemsClimate change adaptationExcrement fertilisersEcological environmentLivestock breeding
The invention relates to the technical field of organic carbon fertilizer and discloses a method for preparing solid organic carbon fertilizer with livestock breeding waste being a raw material. The method includes the steps that a, livestock excrement is stirred evenly, and the water and pH value are adjusted; b, the preprocessed livestock excrement is conveyed into a hydrothermal carbonization oven, and a carbonized product is subjected to dehydration, wet granulation and drying to obtain the solid organic carbon fertilizer. The low-temperature hydrothermal carbonization technology is adopted for converting the livestock breeding waste into the organic carbon fertilizer, the preparation technology is simple and easy to implement, the problem that the ecological environment of the breeding industry is polluted is solved, and the value of the breeding waste is brought into full play. The technology is put into the market to generate great economic benefits and environmental benefits.
Owner:ZHEJIANG FORESTRY UNIVERSITY
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