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Anti-bacterial liquid adhesive bandage and preparation method thereof

A band-aid and liquid technology, applied in medical science, absorbent pads, bandages, etc., can solve problems such as inability to effectively prevent wound infection, long wound healing time, and few products on the market, achieving no allergies and drug resistance, and promoting wound healing. Good effect of healing and water repellency

Active Publication Date: 2016-10-12
严锋
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The research on liquid band-aids emerged as the times require. At present, there are also studies on liquid band-aids, such as ZL200410031161.3, CN 102258804 A, and the research on them is also deepening. However, there are few marketed products with significant wound-protecting and antibacterial effects.
It is especially insufficient for the busy and fast modern society and cannot be waterproof, resulting in long wound healing time and inability to effectively prevent wound infection and other shortcomings

Method used

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  • Anti-bacterial liquid adhesive bandage and preparation method thereof
  • Anti-bacterial liquid adhesive bandage and preparation method thereof
  • Anti-bacterial liquid adhesive bandage and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Present embodiment provides a kind of antibacterial liquid band-aid, and it comprises the component of following parts by weight:

[0031] 5 parts of polymethyl acrylate;

[0032] 20 parts of nitrocellulose;

[0033] 200 parts of ethanol;

[0034] 20 parts of butyl acetate;

[0035] 10 parts of ethyl acetate;

[0036] 50 parts of ether;

[0037] 1.5 parts of camphor;

[0038] 10 parts castor oil;

[0039] 5 parts of polydimethylsiloxane;

[0040] 0.3 parts of nano-silver particles (prepared by conventional liquid-phase chemical reduction method or purchased directly, the same below);

[0041] The preparation method of above-mentioned antibacterial liquid band-aid, it comprises the following steps:

[0042] (a) Dissolve the formulated amount of the cellulose ether and polyacrylate in the mixed solution of ethanol, ethyl acetate, butyl acetate and ether, after mixing and stirring (stirring speed is 500rpm), add the formulated amount of polydimethyl base siloxane ...

Embodiment 2

[0051] This embodiment provides an antibacterial liquid wound protection solution, the preparation method of which is basically the same as that in Example 1, except that it includes the following components in parts by weight,

[0052] 30 parts of polyethyl acrylate;

[0053] Carboxymethyl cellulose 10 parts;

[0054] 30 parts of butyl acetate;

[0055] 15 parts of ethyl acetate;

[0056] 180 parts of ethanol;

[0057] 25 parts of ether;

[0058] 1.2 parts of camphor;

[0059] 8 parts castor oil;

[0060] 1 part of polydimethylsiloxane;

[0061] 0.25 parts of nano silver particles;

[0062] Its cytotoxicity test, skin irritation test result are similar to embodiment 1, and antibacterial test result is as image 3 shown.

Embodiment 3

[0064]This embodiment provides an antibacterial liquid wound protection solution, the preparation method of which is basically the same as that in Example 1, except that it includes the following components in parts by weight,

[0065] 9 parts of polybutyl acrylate;

[0066] 12 parts of ethyl cellulose;

[0067] 10 parts of butyl acetate;

[0068] 20 parts of ethyl acetate;

[0069] 160 parts of ethanol;

[0070] 5 parts of ether;

[0071] 0.6 parts of camphor;

[0072] 6 parts castor oil;

[0073] 2 parts of polydimethylsiloxane;

[0074] Nano-titanium oxide 0.1 part;

[0075] Its cytotoxicity test, skin irritation test result are similar to embodiment 1, and antibacterial test result is basically consistent with embodiment 2, and the survival rate of escherichia coli, Staphylococcus aureus and Candida albicans is respectively 5%, 3%, 3%. 8%.

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Abstract

The invention relates to an anti-bacterial liquid adhesive bandage and a preparation method thereof. The anti-bacterial liquid adhesive bandage comprises, by weight, 10-20 parts of cellulose ether, 5-30 parts of polyacrylate, 150-200 parts of ethanol, 10-30 parts of butyl acetate, 10-20 parts of ethyl acetate, 0.5-1.5 parts of camphor, 5-10 parts of castor oil, 1-5 parts of polydimethylsiloxane and 0.1-0.3 part of anti-bacterial nano particles. After being smeared to a wound, the anti-bacterial liquid adhesive bandage has effects of analgesia, convergence, bacteriostasis, wound healing promotion and the like; the isolation performance is good, bacteria and foreign matter can be prevented from entering the wound, bacteria and fungi on the surface of the wound can be killed, infection is reduced, and the waterproof performance is good. The anti-bacterial liquid adhesive bandage is suitable for wounds different in size, shape and position; after smearing of the anti-bacterial liquid adhesive bandage, a formed film has a certain elasticity, and the coated part can move freely. The anti-bacterial liquid adhesive bandage does not lead to allergy and drug resistance and is high in safety. The anti-bacterial liquid adhesive bandage has no obvious irritation and is convenient to carry and use.

Description

technical field [0001] The invention belongs to the field of medical dressings, and relates to a liquid band-aid, in particular to an antibacterial liquid band-aid and a preparation method thereof. Background technique [0002] Small-area wounds in daily life are mostly treated with alcohol or iodine disinfection first, and then wrapped or protected with gauze or band-aids. Although they can protect the wound surface, there are certain disadvantages. For example, gauze or band-aids are not suitable for special parts. The dressing of the wound surface needs to be replaced repeatedly, which may cause secondary damage to the wound. At the same time, the air permeability is poor after wrapping, and the water vapor and sweat secreted by the wound cannot seep out in time, which will soak the local skin and easily lead to secondary infection of bacteria. , and gauze or band-aid dressing cannot completely isolate the wound from contact with the outside world, and it is easy to cause...

Claims

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Application Information

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IPC IPC(8): A61L15/24A61L15/26A61L15/28A61L15/46
CPCA61L26/0014A61L26/0019A61L26/0023A61L26/0066A61L2300/102A61L2300/104A61L2300/404A61L2300/412C08L33/04C08L1/28C08L83/04
Inventor 严锋
Owner 严锋
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