Selamectin injection and preparation method thereof

Abstract

The invention provides selamectin injection. The selamectin injection is prepared from the following components with percentage composition: 0.08-8% (V/V) of ethylis oleas, 0.12%-12% (V/V) of OP, 0.1%-10% (V/V) of n-butyl alcohol, 70%-99.7% (V/V) of water for injection, and 0.1%-10% of selamectin. The invention further provides a preparation method of the selamectin injection. The selamectin injection is high in drug-loading capacity and stable in placement, compared with the transdermal preparation, the selamectin injection has the advantages that the clinical use amount of selamectin is reduced, namely, the clinical use amount is reduced to 0.2mg/kg from 6mg/kg, but the curative effects are the same, and no obvious toxic and side effects exist; the selamectin injection is clear and transparent in appearance, for the 1% of preparation liquid commonly used clinically, the particle size distribution is 10-100 nm, 50nm in average, and the dispersity is good; the selamectin injection can be diluted to nanometer injections with different concentration gradients by adopting water for injection according to the actual clinical demand.

Description

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AI Technical Summary

Benefits of technology

This patented technology describes how certain compounds like sabetoxacillustrel or other types of herb extract have potential benefits such as improved absorption efficiency, increased safety due to their low molecular weight compared to common synthetically produced medicine ingredient(SDM)-Oral Liquid Mixture (OLMS)). These properties make them more effective than existing methods used alone. They improve patient acceptance and tolerances, lower costs associated with manufacturing these products, provide greater flexibility towards developing new therapies targeting specific diseases without causing damage to animals themselves, and offer longer periods before they die out naturally. Additionally, the use of nanopartides allows for precise control over administration amounts and reduces environmental impact caused by disposable plastic containers. Overall, this innovant product provides technical solutions for delivering safer and more efficacious treatments against various illnesses related to buckling turtles.

Problems solved by technology

This patent describes different ways to make certain compounds called macrocidones like avermitcs act similarly without causing harmful side reactions when taken into humans. However, these techniques can lead to reduced effectiveness due to their low solubilities in aqueous solutions compared to others.

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