Wireless infrared remote control optogenetic system

Abstract

The invention discloses a wireless infrared remote control optogenetics system. The infrared transmitting end includes a power driver board, an infrared emitting tube light strip, a signal source, and a 5V power supply; the infrared receiving end includes an infrared receiving tube, a 3.7V lithium battery, a comparison circuit and a blue light-emitting diode. Use the signal source to control the on-off of the power drive board to control the on-off of the infrared emission tube light strip, so that the brightness of the infrared emission tube light strip is basically the same and is turned on and off synchronously, and the infrared receiving tube receives the infrared signal from the infrared emission tube light strip. , the blue infrared diode is controlled to turn on and off through the comparison circuit, and the light signal of the blue light-emitting diode is introduced into the living body cells through the optical fiber to realize effective light stimulation. The invention can realize long-distance wireless control in the experiment box, is small in size, highly integrated and compact in structure, can respond accurately and timely to the remote control signal of the signal source, has a large range of infrared remote control, and will not affect the free movement of mice in a wide range , which is conducive to large-scale behavioral experiments.

Description

technical field [0001] The invention relates to a method and system for optical stimulation of optogenetic technology, in particular to a wireless infrared remote control optogenetic system. Background technique [0002] Optogenetics is a method of precisely controlling cell activity by combining optical and genetic techniques. Using optogenetics, neuroscience researchers can deeply explore the relationship between neurons in a nucleus. Position and relationship, understand the intrinsic interaction between multiple nuclei, and thus have a clearer understanding of the brain structure and the tectonic function of the nervous system. In addition to basic neuronal structure research, more importantly, using this set of equipment and some animal disease models, it is possible to explore common neurological diseases such as Parkinson's syndrome, Alzheimer's disease, depression, etc. under living conditions. Brain pathological changes, understanding of its intrinsic neuronal path...

AI Technical Summary

Problems solved by technology

However, the domestic and foreign optogenetic device production markets are still in their infancy.

[0004] At present, optogenetic devices are mostly wired devices, which use optical fiber to transmit stimulating light or require the mouse's head to be fixed, while the wireless device is too large and heavy to restrict the free movement of the mouse, so it is impossible to distinguish whether it is due to the light stimulation or the device. The restrictions have an impact on the behavior of mice, which greatly affects the scientific nature of the experiment

In addition, the use of wireless charging in wireless power supply also increases the complexity and cost of the system, making it impossible for biological experiments to be carried out in ordinary biobehavioral experiment boxes.

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