Preparation method of kidney invigorating and blood nourishing pill

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a preparation method of a kidney invigorating and blood nourishing pill. The kidney invigorating and blood nourishing pill comprises polygonum multiflorum, Chinese angelica, black beans, radix achyranthis bidentatae, tuckahoe, cuscuta chinensis, fructus psoraleae and wolfberry fruits. Processed honey and conditioners are further added into the kidney invigorating and blood nourishing pill, addition weight of the conditioners is 10-30% of total weight of raw materials, the conditioners comprise Chinese yam, licorice and astringing intestine and relieving diarrhea drug, the Chinese yam is used for alleviating heavy turbid and sticky greasy characteristics of the polygonum multiflorum, the licorice is used for improving deficiency of spleen and stomach, lassitude and debilitation of patients and relieving toxicities of the pill, the astringing intestine and relieving diarrhea drug is used for adsorbing intestinal harmful substances and decreasing intestine peristalsis, and the weight ratio of the Chinese yam, the licorice and the astringing intestine and relieving diarrhea drug is (2-3):1:(0.3-0.5). The prepared kidney invigorating and blood nourishing pill can be used for counteracting adverse reaction of gastrointestinal tracts of the polygonum multiflorum in the pill.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a preparation method of kidney-tonifying and blood-nourishing pills. Background technique [0002] Nourishing the kidney and nourishing blood pills comes from "Compendium of Materia Medica", according to the book: "At the beginning of Jiajing period in Ming Dynasty, Shao Yuanjie's real person used Qibao Meiran Dan to serve as bait for Emperor Shizongsu, and he gave birth to emperor's heirs. Therefore, the prescription of Polygonum multiflorum is very popular in the world. Since then, Qibao Meiran Dan has become famous and has become a famous prescription for health preservation; it has been used until now, and it is the first of the ten famous anti-aging prescriptions; in 1991, it was included in the drug standard of the Ministry of Health and renamed as Bushen Yangxue Pill; in 2013 The annual income is the third supplement of the 2010 edition of ...

AI Technical Summary

Problems solved by technology

[0004] At present, there are mainly the following points of view on the mechanism of toxicity caused by Polygonum multiflorum and its products: (1) The toxic components of Polygonum multiflorum are mainly anthraquinones, such as emodin, rhubarb fen, rhein, emodin methyl ether, etc. It can cause symptoms of gastrointestinal discomfort, skin allergies, liver damage, nausea, vomiting, fatigue, diarrhea, abdominal pain, borborygmi, etc.; in severe cases, paroxysmal tonic convulsions and even respiratory paralysis may occur; anthraquinones have Similar to the action of adrenal cortex hormone, it has a certain toxic effect on the liver, which can be recovered after stopping the drug, which is a reversible damage; (2) It is related to genetic liver metabolic enzyme defects, such as the liver isoenzyme metabolism and its protein Deficiency or lack of secretion; the liver plays a very important role in the metabolism and disposal of exogenous chemical substances, because there are many metabolic enzymes in the liver; when the patient lacks this enzyme system, it will cause the drug to accumulate in the body and appear drug The adverse reactions caused by this cause have significant familial characteristics and large individual differences; (3) During the body's metabolism, certain hepatotoxic substances are produced, causing lipid peroxidation in liver cells to cause Liver cell necrosis

(4) A certain toxic substance interferes with the uptake and secretion of bile by liver cells, destroys the receptors carrying bile salts in the cell membrane, affects the activity of the sodium-potassium pump in the cell membrane, and causes abnormalities in the normal structure and metabolic function of liver cells

[0006] (1) The dosage of Radix Polygoni Multiflori in Bushen Yangxue Pills is large, and some patients will experience gastrointestinal discomfort symptoms after taking them. If they are taken continuously for a long time, the medicine will accumulate in the body, cause hepatitis, and produce adverse reactions. Recoverable means reversible damage;

[0007] (2) Familial adverse reactions, those who are allergic to Polygonum multiflorum, and those with allergic constitution, will have adverse reactions after taking small doses; those with hereditary liver metabolic enzyme defects, taking this product will cause drug-induced liver damage due to accumulation of drugs in the body

[0012] However, this problem cannot be solved simply by reducing the dosage of Radix Polygoni Multiflori, nor by excessively prolonging the processing time and reducing the content of anthraquinones; It has pharmacological effects such as laxative, as well as anti-tumor and immune-enhancing effects. It is one of the main active ingredients in Polygonum multiflorum