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Rh group incompatibility therapeutic apparatus

A therapeutic instrument, rh blood type technology, applied in alkali metal compounds, blood circulation treatment, other medical devices, etc.

Active Publication Date: 2017-01-04
ATTACHED OBSTETRICS & GYNECOLOGY OSPITAL MEDICALCOLLEGE ZHEJIANG UNIV +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

But so far there is no report on the design of the treatment of blood group incompatibility hemolytic disease according to the above mechanism

Method used

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  • Rh group incompatibility therapeutic apparatus
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  • Rh group incompatibility therapeutic apparatus

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Experimental program
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Embodiment Construction

[0012] figure 1 It is an application schematic diagram of the Rh blood group incompatibility hemolytic disease therapeutic apparatus proposed according to the present invention.

[0013] figure 2 It is a schematic diagram of the internal structure of the plasma separator proposed according to the present invention.

[0014] image 3 is a schematic diagram of the internal structure of the adsorber proposed according to the present invention.

[0015] figure 1 Among them, one end of the arterial blood line tube (1) is connected with the arterial blood vessel, and the other end is connected with the plasma separator (4) through the heparin pump (2) and the blood pump (3), and the plasma separator (4) is connected through the plasma pump (6) ) and circulation pipeline (7) are connected with two parallel adsorbers (8) and adsorber (9), and then connected with circulation pipeline (10) and venous pipeline (5) in turn, and venous pipeline (5) The other end is connected to the v...

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Abstract

The invention relates to an Rh group incompatibility therapeutic apparatus in the field of medical science. The Rh group incompatibility therapeutic apparatus is characterized in that rhesus monkey red blood cells containing human common Rh antigen are alternately washed by PB lysate with the osmotic concentration of 25 and 35mmol / L, ghost cells dialyzed with hemoglobin, retaining Rh antigenicity and capable of adsorbing an Rh antibody are prepared and fixed to agarose with special concentration together with the Rh antibody prepared by immunology according to a specific ratio, the agarose is placed into a cylindrical adsorber made of high-biocompatibility materials, antibody valence from high to low and agarose concentration from low to high are formed from a sample inlet end to a sample outlet end, the ghost cells are uniformly distributed, red blood cell destruction products of patients suffering from group incompatibility can be effectively intercepted by the agarose with gradually increased special concentration and gradually decreased molecular micropores at the sample inlet end and the sample outlet end and a mesh screen at an outlet of the adsorber, and a novel therapeutic method for maternal fetal Rh group incompatibility does not remove plasma components and avoids toxic and side effects.

Description

technical field [0001] The invention relates to a Rh blood group incompatibility hemolytic disease treatment instrument used in the medical field, which is mainly used for removing anti-fetal red blood cell antibodies and red blood cell lysates in plasma of pregnant women with maternal-fetal Rh blood group incompatibility. Background technique [0002] The fetus inherits half of the genetic components of the father and half of the mother, and the fetal red blood cells can carry antigens from the father, showing that the blood type of the fetus is different from that of the mother. When the fetal red blood cells enter the mother's blood circulation, the mother's immune system is induced to produce antibodies, and the antibodies pass through the placenta and enter the fetal blood circulation system, combining with fetal red blood cells, causing fetal red blood cells to be destroyed, resulting in maternal-fetal blood group incompatibility hemolytic disease in fetuses and newborn...

Claims

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Application Information

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IPC IPC(8): A61M1/36B01J20/28B01J20/30C12N5/078C07K16/18C12N5/0781C12N5/0783C12N5/20C12R1/91
CPCA61M1/3621A61M1/3633A61M1/3672A61M1/3687A61M2202/0413A61M2205/75B01J20/28047C07K16/18C12N5/0635C12N5/0636C12N5/0641A61M2202/0021
Inventor 翁炳焕李兰娟
Owner ATTACHED OBSTETRICS & GYNECOLOGY OSPITAL MEDICALCOLLEGE ZHEJIANG UNIV
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