The invention relates to a
blood purification therapeutic apparatus for treating mother-
fetus Rh blood group incompatibility in the medical field. The
blood purification therapeutic apparatus is characterized in that PB lysates with osmotic concentrations of 25 mmol / L and 35 mmol / L respectively are prepared; rhesus red blood cells containing a common Rh
antigen of human red blood cells are alternately washed to prepare ghost cells which dialyze
hemoglobin but retain the Rh
antigen and can effectively adsorb an Rh
antibody; purifying agents with the ghost
cell concentration of 95% are prepared by using
agarose, with the concentrations of 0.9%, 1.0%, 1.1%, 1.2% and 1.3% respectively, molten at 100 DEG C and then thermally insulated at 42 DEG C; from
high concentration to low concentration of the
agarose, 55-65ml of the purifying agents are sequentially added into a cylindrical container made of a highly-
biocompatible material so as to form an adsorber in which ghost cells in the purifying agents are uniformly distributed from the sample inlet end to the sample outlet end, but
agarose concentration gradually increases from the sample inlet end to the sample outlet end; the adsorber is used for clearing away the Rh
antibody in
plasma of a filtering purifier and macromolecular pathogenic substances generated by destroyed red blood cells so as to treat a hemolytic
disease caused by the Rh blood group incompatibility.