Bicarbonate physiological balanced solution and preparation method thereof

A physiological balance liquid, bicarbonate technology, applied in pharmaceutical formulations, medical preparations containing active ingredients, aluminum/calcium/magnesium active ingredients, etc. Hyperlactatemia, unfavorable liver transplantation, etc., achieve the effect of formula conforming to physiology, preventing immune stress and oxidative stress, and improving metabolic conditioning
CN101721424BInactive Publication Date: 2012-07-25曾因明 +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
曾因明
Publication Date
2012-07-25
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a bicarbonate physiological balanced solution which belongs to the field of infusion preparations and is prepared form the following raw materials: sodium chloride, potassium chloride, calcium chloride, magnesium sulfate, sodium bicarbonate, citric acid, trisodium citrate and optional glucose. All the raw materials are accurately weighed according to corresponding portions, and dissolved in water for injection; the volume is determined; CO2 gas is introduced; the pH value is adjusted; and the solution is filtered, filled, packed, sterilized, labeled and then stored at room temperature. The solution has the advantages that ion components and a penetration concentration are similar to those of extracellular fluid and have physiological performance. The balanced solution is suitable for supplementing the extracellular fluid by injection, intravenous drip or oral administration, has an adjustment function for acid-base balance, and is also used as a surgical washing fluid or buffering solution.
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Description

technical field

[0001] The invention relates to a large transfusion preparation, in particular to a bicarbonate physiological balance liquid. It is a balance solution whose ionic composition and osmotic pressure are closer to extracellular fluid. It is suitable for supplementing extracellular fluid through injection, intravenous infusion or oral route. It can regulate acid-base balance and can also be used as a surgical flushing fluid. or buffer solution. Background technique

[0002] There are three main types of balance solutions currently used in the medical field: Ringer’s solution (RS), Lactated Ringer’s solution (LRS) and Acetated Ringer’s solution (ARS).

[0003] From 1880 to 1883, Sydney Ringer (1835-1910), a British physiologist and clinician, accidentally used tap water to prepare frog myocardial perfusion fluid, and found that its myocardial contractility was stronger than that of saline prepared with distilled water. The contained traces of potassium / calcium io...

Claims

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