56results about How to "Reduce lipid peroxidation" patented technology

This invention is based on the observed oxidative stress and increased risk on cardiovascular diseases in subjects with increased lipid peroxidation, in particular with women using oral contraceptives and in hormone replacement therapies. The invention provides compositions and combinations, particularly useful in preventing and or reducing the increased lipid peroxidation in subjects in need thereof. These compositions are based on the synergistic combination of zinc and/or a hydroxyl radical scavenger in reducing lipid peroxidation.

The present invention relates to a cosmetic, dietary supplement, or pharmaceutical composition for oral ingestion or topical application to the skin comprising effective amounts of a tocopherol quinone, tocopherol quinol, plastoquinol, menaquinol, or phylloquinol compound, or any combination thereof as a method for preventing free radical oxidation or preventing or treating environmental skin damage including photoaging, trauma, discoloration, dryness, thickness, elasticity, or wrinkles.

A do-it yourself test kit as a diagnostic agent for the detection of malonyldiadeyde and other aldehydes in the urine, which are formed in the course of the lipid peroxidation process caused by the free radicals. Also disclosed is a process for the preparation of the test, including suggested formulations of antioxidants as body's protectors against oxidative stress to the cells and help to reduce the risk of developing diseases due to the attack of free radicals.

A traditional Chinese medicine composition for treating thrombophlebitis belongs to the field of medicines, and comprises the following raw materials by weight: astragalus 25-32 g, dangshen 12-17 g, angelica sinensis 13-17 g, ligusticum wallichii 14-16 g, spina gleditsiae 13-17 g, radix paeoniae rubra 14-17 g, radix aucklandiae 8-11 g, akebiaquinata 9-12 g, pangolin 7-11 g, rheum officinale 9-11 g, and honeysuckle stem 18-22g. Through the selection of the traditional Chinese medicines, characteristics of all the medicines are fully used, and all the medicines interact to relax tendons and activate collaterals, promote blood circulation to remove blood stasis, reduce phlegm and resolve masses, and the treatment effect on the thrombophlebitis is remarkable.

A fermented tea produced by primary-drying tea material leaves by means of a primary tea rolling dryer (primary drying step) to adjust the moisture content of raw leaves (tea material leaves) of bancha with low qualities (the second crop of tea, the third crop of tea, the shuto-bancha, the skiffed leaves of tea, and the like) to a constant moisture; subsequently, providing them in a tea roller (tea rolling step); adding loquat leaves during the tea rolling step in order to knead loquat leaves together with the tea material leaves; and fermenting and drying the kneaded tea material leaves and loquat leaves. The fermented tea is formed into a composition having, as an active component, the fermented tea obtained by tea-rolling processing of tea material leaves and loquat leaves, and an extract contained in the fermented tea.

The invention provides a combination for protecting peroxide injury of myocardium. The combination comprises the following raw materials (parts by weight of each raw material are shown in brackets): coenzyme Q100 (5 to 50), L-carnitine (10 to 500), and octocosanol (10 to 100). The combination can lessen lipid peroxidation of a myocardium cell membrane and improve the activity of antioxidant enzymes such as SOD, GSH-Px and CAT, thereby protecting the peroxide injury of the myocardium and delaying or eliminating sports fatigue.

The invention discloses a technology of using ocean phaffiarodozyma for producing feed additive astaxanthin in a fermentation mode. The technology includes the steps that glucose, yeast extract powder and the like serve as main raw materials to carry out liquid state submerged fermentation cultivation of special type yeast strains; fermenting-ripening astaxanthina saccharomycetes liquid is pumped into a horizontal low speed centrifuge to be centrifuged; astaxanthina saccharomycetes residue suspension liquid obtained through centrifugation is squeezed in a box pressure filter until the solid content is about 30%, the suspension liquid is moved into a fluidized bed and dried at low temperature till the moisture content is reduced to below 5%, and then the feed additive astaxanthin with the astaxanthin content of 10% is obtained through pulverizing and filtering. The technology has the advantages that as the astaxanthin production capacity strains are matched with a highly shared and complementary product extracting and purification technology, two most important natural antioxidant chiral drug intermediates and the feed additive are simultaneously obtained through one production line, the production cost is reduced, and the productivity benefits of the astaxanthin are increased.

The invention provides a eucalyptus leaf extract natural meat quality improver, and a preparation method and a purpose thereof. According to the invention, eucalyptus leaves are dried in a shade at a place protected from light; the eucalyptus leaves are crushed to 40-60 meshes; the eucalyptus leaf is added into an extraction tank; 40-95% ethanol is added, and the eucalyptus leaf is extracted twice; filtrates are combined, and the combined filtrate is added into a concentration device; the material is concentrated until only water is left; and spray-drying is carried out, such that the meat quality improver is obtained. The meat quality improver provided by the invention has a total phenol content of 25-40%. The meat quality improver comprises 6-12% of evening primrose element B, 1-2% of tellimagrandin I, and 0.1-0.15% of 1, 2, 3, 4, 6 penta-alloyl glucose. The natural meat quality improver provided by the invention is used as a livestock and poultry feed additive, and has the effects such as body antioxidant capacity enhancing, lipid peroxidation reducing, meat color brightening, meat tenderness improving, drip loss reducing, and meat shelf live prolonging.

Disclosed are uses of isotopically modified polyunsaturated compounds for treating, ameliorating or inhibiting the progression of a neurodegenerative disease or condition related to tauopathy in a subject in need thereof. In certain embodiments, the isotopically modified polyunsaturated compounds are deuterated polyunsaturated fatty acids or derivatives thereof.

The invention relates to a traditional Chinese medicine composition fro treating thrombophlebitis. The traditional Chinese medicine is prepared by the following raw materials by weight part: 25-32g of astragalus mongholicus, 12-17g of codonopsis pilosula, 13-17g of angelica sinensis, 14-16g of ligusticum wallichii, 13-17g of spina gleditsiae, 14-17g of root of common peony, 8-11g of elecampane, 9-12g of akebiaquinata, 7-11g of manis pentadactyla, 9-11g of rheum officinale and 18-22g of honeysuckle stem. According to the traditional Chinese medicine composition, the traditional Chinese medicines are selected and matched with each other, and the characteristics of the medicines can be fully utilized, so that the traditional Chinese medicine composition relieves rigidity of muscles and activates collaterals, promotes blood circulation to remove blood stasis, dissolves phlegm and removes stasis, and has obvious effects on the treatment of thrombophlebitis.

There are presented topical formulations and methods of applying these formulations in therapeutically effective amounts directly to areas of the human skin to remediate and to counter effects that are commonly regarded as aging. The formulations address the effects on the skin of UV light, High Energy Visible (HEV) light, blue light, and Urban Dust as well as remediating fine lines and age-related localized melanin concentrations (“age spots”), improving the uniformity of skin tone (reduction in skin redness) and enhancing the brightness of the skin to provide a more youthful appearance. Skin treated with the formulations also exhibit a reduction in the depth and prominence of wrinkles, a marked reduction in harmful reactive oxygen species in the treated skin, and a reduction in lipid peroxidation caused by Urban Dust.

A method for treatment of acute lung injury by use of kirenol is revealed. The method includes a step of applying an effective dose of kirenol to an individual in need for reducing hyaline membrane formation, neutrophil infiltration, pulmonary edema, and pulmonary oxidative stress so as to treat acute lung injury.

The invention relates to the technical field of purification of triterpenoids, medicine and health foods and particularly relates to a method for extracting and purifying triterpenoids from apple pomace and application of the triterpenoids. The method comprises the following steps of mixing dried 100-120-mesh apple pomace serving as a raw material and 95% ethanol solution at a ratio of the material to liquid being 1:18, carrying out ultrasonic extraction and drying filtrate to obtain an apple pomace triterpenoid extract; mixing the extract and petroleum ether according to a ratio of the material to liquid being (1:30)-(1:40), repeatedly washing with ultrasonic waves for 4-6 times at 40-60 DEG C and 40-60 minutes each time and drying filter residue to obtain an apple pomace triterpenoid crude extract; and finally adsorbing and eluting triterpenoids in apple pomace by macroporous resin to obtain an eluent, concentrating and drying the eluent to obtain an apple pomace triterpenoid purified product. The invention further discloses main active ingredients (ursolic acid and oleanolic acid) in the apple pomace triterpenoid crude extract and the purified product and two extracts have the characteristic of scavenging free radical and antioxidant capacity and have significant improving and protecting effect on acute liver injury.

The invention discloses a lotus craft beer brewing process and flow, and belongs to the technical field of beer. Lotus craft beer is brewed from Australia malt, burnt malt, aqueous extract of folium forsythia, aqueous extract of honeysuckle flower, aqueous extract of semen armeniacae amarum, aqueous extract of houttuyniae herba, aqueous extract of liquorice root, aqueous extract of lophatherum herb, aqueous extract of chicory, purified water and additives by mixing and sequentially carrying out saccharification, fermentation, filtration and sterilization. According to the invention, on the basis of using traditional beer raw materials including water, malt and hops, the folium forsythia (extract), the honeysuckle flower (extract), the semen armeniacae amarum (extract), the houttuyniae herba (extract), the liquorice root (extract), the lophatherum herb (extract) and the chicory (extract) are added in different production processes; intrinsic active substances of the seven traditional Chinese medicines are sufficiently played under the action of yeast biological fermentation; and the aims of invigorating stomach, tonifying qi, eliminating carbuncle and eliminating stagnation are fulfilled.

The present invention relates to the treatment of sepsis and sepsis-associated acute kidney injury (SA-AKI). More specifically, it relates to cilastatin for use in a method of treating sepsis and/or SA-AKI and reducing its associated mortality, in a mammalian subject. It is further directed to methods for treating sepsis and/or SA-AKI; and to pharmaceutical compositions for use in the methods of the invention.

An extract of the skin or peel of passion fruit is prepared. The extract has the effect of ameliorating the symptoms of inflammation disorders, including asthma and osteoarthritis, in mammals, including humans, when administered in an effective amount.

A compound ambroxol hydrochloride composition and a preparation method therefor, which relate to the field of medicine. 0.1%-99.9% by mass of ambroxol hydrochloride and 99.9%-0.1% by mass of scopolamine serving as main ingredients and mannitol are added into water for injection; stir to dissolve, then adjusting to pH 5.0 by adding an NaOH solution; add 0.1% of activated carbon with stirring for 30 minutes; filter out the activated carbon, and then filtering the liquid with 0.45 μm and 0.22 μm microporous filter membranes; fill the filtered liquid into a large plate or a vial; send into a lyophilizer, cool to −40° C., and hold the temperature for 2 hours; warm to −5° C. to 0° C. slowly to lyophilize the liquid, heat to 35° C., and hold the temperature for 3 hours; take out of the lyophilizer after lyophilizing to obtain a lyophilized powder injection containing ambroxol hydrochloride and scopolamine; crush the lyophilized powder injection under a sterile conditions, and sieve with a 180-mesh sieve to obtain sterile lyophilized powder containing ambroxol hydrochloride and scopolamine; and prepare various dosage forms by using the lyophilized powder as a raw material.

The invention discloses a preparation method of a slow-release photosynthetic promoting compound fertilizer. The preparation method comprises the following steps: (1) mixing plant straw, livestock andpoultry manure, fulvic acid and mushroom dregs, pulverizing, sending into a fermentation tank, and carrying out sealed fermentation to obtain a decomposed fermentation material; (2) air-drying the decomposed fermented material, crushing, adding oxidized glutathione and inorganic nutrient powder into the crushed material, uniformly mixing, and feeding into a granulator for granulation; (3) mixingpolyvinyl alcohol and water, heating and stirring until the polyvinyl alcohol and the water are completely dissolved, and sequentially adding chitosan and silicon dioxide to obtain a coating agent; and (4) immersing the obtained particles into a coating agent, taking out the particles, and blow-drying the particles to constant weight at normal temperature to obtain the compound fertilizer. The compound fertilizer is simple in preparation method, easy for large-scale production in factories, balanced in nutritional ingredients, and capable of powerfully promoting photosynthesis during plant growth, and provides powerful technical support for reducing planting labor input and increasing crop yield.

The invention relates to the technical field of beer, and discloses beer having effects of nourishing yin and tonifying kidney and a preparation process of the beer. The beer having effects of nourishing yin and tonifying kidney is prepared by mixing Australia malt with burnt malt, mulberry fruit powder, lotus seed powder, oyster peptide, a raspberry extract, a wolfberry fruit extract, purified water and an additive; and performing saccharifying, performing fermenting, performing filtering and performing sterilizing to brew. The beer having effects of nourishing yin and tonifying kidney is prepared from the following components in parts by weight: 535 parts of the Australia malt, 15 parts of the burnt malt, 6 parts of the mulberry fruit powder, 5 parts of the lotus seed powder, 1-3 parts of the oyster peptide, 3-5 parts of the raspberry extract and 4-6 parts of the wolfberry fruit extract. On the basis of using traditional beer raw materials of water, malt and hops, in different production processes, according to compatibility of monarch, minister, assistant and guide of the traditional Chinese medicines, intrinsic active substances of the traditional Chinese medicines of all the components are sufficiently exerted under the action of biological fermentation of yeast, and the purpose of the beer having effects of nourishing yin and tonifying kidney is achieved.

An extract of the skin or peel of passion fruit is prepared. The extract has the effect of ameliorating the symptoms of inflammation disorders, including asthma and osteoarthritis, in mammals, including humans, when administered in an effective amount.

An extract of passion fruit is prepared. The extract has the effect of lowering blood pressure and serum nitric oxide levels in mammals. The extract also provides a hepatoprotective effect, as well as antioxidant and anti-inflammatory effects in mammals. A novel compound was identified in the extract and given the name edulilic acid.

The invention discloses a composition applied to an anti-wrinkle firming multi-effect skin care product. The composition comprises the following raw materials in parts by weight: 4.0 to 8.0 parts of an inonotus obliquus extract and 0.18 to 0.22 part of triethanolamine. The invention further discloses the anti-wrinkle firming multi-effect skincare product and a preparation method thereof. The anti-wrinkle firming multi-effect skincare product comprises the composition, A-phase raw material, B-phase raw material and D-phase raw material, with the balance being water, wherein the A-phase raw materials contain polydimethylsiloxane, caprylic/capric triglyceride, hydrogenated polyisobutene, an emulsifier and 2,6-di-tert-butyl-4-methylphenol; the B-phase raw materials contain glycerinum, betaine,carbomer 2020, ethylenediamine tetraacetic acid disodium salt and propylene glycol; and the phase-D raw materials contain a cross-linked polymer of polydimethylsiloxane and C16-18 alkyl polydimethylsiloxane, and cyclopentasiloxane. The composition and the product provided by the invention have excellent moisturizing, anti-wrinkle and firming effects, and have the effects of fading dark circles and removing under-eye puffiness.

The invention discloses a composition capable of intelligently regulating skin oil-water balance. The composition comprises capryloyl glycine, fragrant citrus extract, pseudoalteromonas fermentation product extract, Laminaria saccharina extract, zinc gluconate, dipotassium glycyrrhizinate and auxiliary components. The composition has the advantages that skin oil-water secretion balance care is performed through multiple approaches by compounding the components, and the skin can fast adapt to different environment conditions and keep a good oil-water balance healthy state.

The invention discloses a traditional Chinese medicine compound composition with an anti-fatigue function and application of the traditional Chinese medicine compound composition. The traditional Chinese medicine compound composition with the anti-fatigue function is prepared from rhodiola rosea, polygonatum kingianum, hairyvein agrimony, ginger, cassia twig and broadleaf holly leaf according to a certain weight percentage. The traditional Chinese medicine compound composition has an obvious effect on improving energy, and is a safe and effective dietary supplement.

Disclosed is a composition of a synergistically effective ratio of an hydroxamic acid, salt and/or a complex thereof and an antioxidant. The composition is effective to reduce or prevent lipid peroxidation upon exposure of a lipid to UV light. Personal care and other formulations are included within the scope of the invention, as are the related methods of increasing the antioxidant potential of an antioxidant, of reducing a rate of peroxidation of constituent lipids in a personal care formulation over a time period and of reducing peroxidation of lipids within mammalian skin cells.