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Preparation method of pomelo peel total flavones and pomelo peel total flavone composition

A technology of grapefruit peel and total flavonoids is applied in the directions of pharmaceutical combinations, medical preparations containing active ingredients, pharmaceutical formulations, etc., which can solve the problems of affecting application, many impurities, and low content of active ingredients, and achieves the realization of dehumidification and drying, and simple operation. Quick, simple effects

Inactive Publication Date: 2017-02-08
滁州先奇工业科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented technology improves upon existing methods such as extracting total flavones (TF) with less purity than desired due to their complexity or lacked effectiveness during production processes. By adding TF into this process instead of relying on traditional techniques like evaporation-based solvents, it becomes easier to handle large amounts of residual material without affecting its quality. Dryers made up entirely of plastic are also simpler but more effective at removing moisture compared to other ways they use. Overall, these technical improvements improve the efficiency and convenience associated with producing medications containing THC compounds.

Problems solved by technology

This patented extracts all flavones out of Pomle Peeler (Prunus salicina), but it also contains other compounds that are difficult or expensive to make medicine because they have high levels of unwanted substances like quercetin). These contaminants can be harmful if taken too much by people who may want them through their medication without being able to use these drugs effectively due to its poor absorption properties.

Method used

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  • Preparation method of pomelo peel total flavones and pomelo peel total flavone composition
  • Preparation method of pomelo peel total flavones and pomelo peel total flavone composition
  • Preparation method of pomelo peel total flavones and pomelo peel total flavone composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Take 1000g of fresh pomelo peel, wash and mince it, add ethanol to make the alcohol content reach 75% by volume, put it into a water bath at 90°C to fully condense and reflux to obtain a crude extract, and use a vacuum filter to extract it under reduced pressure. Filtrate, collect the filtrate, concentrate under reduced pressure, spray dry the concentrated solution, granulate, and dry the granules to obtain the total flavonoids extract of pomelo peel.

[0020] In the preparation method of the total flavonoids of pomelo peel, the weight of adding ethanol is 10 times of the weight of pomelo peel.

[0021] Particle drying device used in the preparation method of total flavonoids of pomelo peel, see Figure 1-2 , including: a casing 3, a drum 5 and a feed hopper 7, the casing 3 is cylindrical and fixedly installed on the bracket 2, the bottom of the casing 3 is provided with a discharge port 1, and the drum 5 is installed therein. Several buckets 4 are fixed on the drum 5....

Embodiment 2

[0026] Take 1000g of fresh pomelo peel, wash and mince it, add ethanol to make the alcohol content reach 75% by volume, put it into a water bath at 90°C to fully condense and reflux to obtain a crude extract, and use a vacuum filter to extract it under reduced pressure. Filtrate, collect the filtrate, concentrate under reduced pressure, spray dry the concentrated solution, granulate, and dry the granules to obtain the total flavonoids extract of pomelo peel.

[0027] In the preparation method of the total flavonoids of pomelo peel, the weight of adding ethanol is 10 times of the weight of pomelo peel.

[0028] The particle drying equipment is the same as above.

[0029] The weight ratio of the total flavonoids, lauric aldehyde, and perillaldehyde of grapefruit peel prepared by the above method is 5:4:2, and prepared into tablets according to the conventional method.

Embodiment 3

[0031] Take 1000g of fresh pomelo peel, wash and mince it, add ethanol to make the alcohol content reach 75% by volume, put it into a water bath at 90°C to fully condense and reflux to obtain a crude extract, and use a vacuum filter to extract it under reduced pressure. Filtrate, collect the filtrate, concentrate under reduced pressure, spray dry the concentrated solution, granulate, and dry the granules to obtain the total flavonoids extract of pomelo peel.

[0032] In the preparation method of the total flavonoids of pomelo peel, the weight of adding ethanol is 10 times of the weight of pomelo peel.

[0033] The particle drying equipment is the same as above.

[0034] The weight ratio of the total flavonoids, lauric aldehyde, and perillaldehyde of grapefruit peel prepared by the above method is 4:6:3, and prepared into tablets according to the conventional method.

[0035] Lauric aldehyde (70%) and perillaldehyde (20%) in the above examples were purchased from Shaanxi AOC B...

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Abstract

The invention provides a preparation method of pomelo peel total flavones. The method comprises the following steps: taking fresh pomelo peel, cleaning, grinding, adding ethanol until the volume percent of ethanol reaches 75%, putting into a 90-DEG C water bath, sufficiently condensing under reflux to obtain a crude extracting solution, carrying out vacuum filtration by using a vacuum filter, collecting the filtrate, concentrating under reduced pressure, drying the concentrated solution and granulating to obtain the pomelo peel total flavone extract. The obtained pomelo peel total flavones have high content, and can be mixed with lauraldehyde and perillaldehyde to prepare the pomelo peel total flavone composition.

Description

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Claims

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Application Information

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Owner 滁州先奇工业科技有限公司
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