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Application of a compound traditional Chinese medicine composition in the preparation of medicines for improving human immunity

A technology of compound Chinese medicine and composition, which is applied in the application field of compound Chinese medicine composition in the preparation of drugs for improving human immunity, and can solve problems such as decreased phagocytosis of macrophages, decreased activity of NK cells, and decreased CD4/CD8 ratio of body weight , to achieve the effect of improving macrophage function, increasing macrophage content, and being easy to popularize and apply

Active Publication Date: 2019-06-18
JIANGSU PROVINCIAL HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, patients will suffer from low immunity after using chemotherapy drugs. Animal experiments have shown that the body weight, spleen index, T lymphocyte proliferation activity, and CD4 / CD8 ratio of experimental mice after 5-fluorouracil intervention were significantly reduced, and leukopenia, Atrophy of immune organs, decreased phagocytosis of macrophages and decreased activity of NK cells

Method used

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  • Application of a compound traditional Chinese medicine composition in the preparation of medicines for improving human immunity
  • Application of a compound traditional Chinese medicine composition in the preparation of medicines for improving human immunity
  • Application of a compound traditional Chinese medicine composition in the preparation of medicines for improving human immunity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A compound combination medicine for improving human immunity, which consists of the following components in parts by weight:

[0028] 15 parts of roasted astragalus, 15 parts of fried Codonopsis, 10 parts of fried Atractylodes macrocephala, 15 parts of poria cocos, 15 parts of Chinese yam, 5 parts of roasted licorice, 10 parts of sun-burned black plum, 10 parts of trigonum, 10 parts of curcuma, 30 parts of Agrimony, Patrinia 30 parts, altogether 11 medicines.

[0029] According to the proportion of the prescription, weigh the above 11 decoction pieces of traditional Chinese medicine, add water 10 times the total weight of the raw material medicine, decoct and extract 3 times, 1 hour each time. Combined decoction, namely decoction.

[0030] The resulting decoction is concentrated to a relative density of 1.10 (measured at 60° C.), added with ethanol until the alcohol content reaches 60%, and left to stand for more than 12 hours. The supernatant was collected by filtrat...

Embodiment 2

[0032] A compound combination medicine for improving human immunity, which consists of the following components in parts by weight:

[0033] 15 parts of Radix Astragalus, 30 parts of Codonopsis pilosula, 10 parts of Atractylodes macrocephala, 20 parts of Poria cocos, 15 parts of Chinese yam, 5 parts of roasted licorice, 10 parts of sun-baked plum, 15 parts of Sanleng, 15 parts of curcuma, 30 parts of Agrimony, Patrinia 30 parts, altogether 11 medicines.

[0034] According to the proportion of the prescription, weigh the above 11 decoction pieces of Chinese herbal medicines, add 20 times the total weight of raw materials in water, decoct and extract 3 times, 1 hour each time. Combine the decoctions, concentrate to a relative density of 1.08 (measured at 60°C), add ethanol until the alcohol content reaches 60%, let it stand for more than 24 hours, filter the supernatant, recycle the ethanol to the utmost, and concentrate to a relative density of about 1.08 ( measured at 60°C). ...

Embodiment 3

[0036] A compound combination medicine for improving human immunity, which consists of the following components in parts by weight:

[0037] 20 parts of Radix Astragalus, 20 parts of Codonopsis pilosula, 15 parts of Atractylodes macrocephala, 15 parts of Poria, 15 parts of Chinese yam, 10 parts of roasted licorice, 15 parts of sun-baked plum, 10 parts of Sanleng, 10 parts of Curcuma, 15 parts of Agrimony, Patrinia 15 parts, totally 11 medicines.

[0038] According to the proportion of the prescription, weigh the above 11 decoction pieces of traditional Chinese medicine, add 5 times the total weight of the raw material in water, decoct and extract 3 times, 1 hour each time. Combine the decoctions, concentrate to a relative density of 1.10 (measured at 60°C), add ethanol until the alcohol content reaches 60%, let it stand for more than 24 hours, filter the supernatant, recycle the ethanol to the utmost, and concentrate to a relative density of about 1.33 ( measured at 60°C). A...

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Abstract

The invention discloses an application of a compound traditional Chinese medicine composition in the preparation of medicines for improving human immunity, wherein the compound traditional Chinese medicine composition comprises the following components in parts by weight: 15-30 parts of Radix Astragali Radix, 15-30 parts of Fried Codonopsis Codonopsis 30 parts, 10-20 parts of fried Atractylodes macrocephala, 15-30 parts of poria cocos, 15-30 parts of Chinese yam, 5-10 parts of roasted licorice, 10-20 parts of roasted ebony, 10-20 parts of trigonum, 10-20 parts of curcuma, crane 15-30 parts of grass, 15-30 parts of Patrinia. The compound combination medicine of the invention has the curative effect of increasing the content of macrophages in the body, can significantly improve the immunity of the human body, and at the same time, the preparation price of the medicine is low, and it is easy to popularize and apply.

Description

technical field [0001] The invention relates to traditional Chinese medicine technology, in particular to the application of a compound traditional Chinese medicine composition in the preparation of medicines for improving human immunity. Background technique [0002] With the change of lifestyle and environmental pollution, the incidence of tumors is increasing year by year. In addition to surgery, most of the first-line chemotherapy for tumor patients is still combined drug therapy based on cytotoxic drugs represented by 5-fluorouracil. Although the use of chemotherapy drugs has eliminated some tumor cells, it also has a certain killing effect on normal cells in the body. Clinically, patients will suffer from low immunity after using chemotherapy drugs. Animal experiments have shown that the body weight, spleen index, T lymphocyte proliferation activity, and CD4 / CD8 ratio of experimental mice after 5-fluorouracil intervention were significantly reduced, and leukopenia, A...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P37/04A61P35/00
CPCA61K36/076A61K36/284A61K36/344A61K36/481A61K36/484A61K36/73A61K36/736A61K36/84A61K36/8945A61K36/902A61K36/9066A61K2236/331A61K2236/39A61K2300/00
Inventor 周锦勇刘沈林陈玉根朱学军
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM