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Marine peptides and fish nucleotides, compositions and use thereof for lowering blood sugar

A technology of fish nucleotides and marine peptides, applied in drug combination, application, food science and other directions, can solve the problem of no contribution to blood sugar control

Active Publication Date: 2021-12-17
FIRMENICH SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In contrast, whey protein hydrolysates did not contribute to glycemic control by either insulin-dependent or insulin-independent mechanisms

Method used

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  • Marine peptides and fish nucleotides, compositions and use thereof for lowering blood sugar
  • Marine peptides and fish nucleotides, compositions and use thereof for lowering blood sugar
  • Marine peptides and fish nucleotides, compositions and use thereof for lowering blood sugar

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0099] A double-blind study involving 12 healthy male testers was conducted with four (4) different diets as described below:

[0100] 1. Diet A : (control diet) casein (30%) + added carbohydrates (55% maltodextrin) + fat (11% medium chain triglycerides (MCT); ie 30g protein from casein per 100g diet.

[0101] 2. Diet B : In the control diet, 10% of casein was replaced by marine peptide (marine protein hydrolyzate) in terms of crude protein (N×6.25); that is, the protein portion of the diet consisted of 3.2% protein from marine peptide and 26.7% from casein protein composition.

[0102] 3. Diet C : 10% of casein as crude protein (N x 6.25) in the control diet was replaced by whey peptides (whey peptide hydrolyzate), ie 3.2 g protein from whey peptides and 26.8 g protein from casein.

[0103] 4. Diet D. : In the control diet, 10% casein was replaced by marine peptides (marine protein hydrolyzate) based on crude protein (N×6.25); that is, the protein portion in the diet...

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Abstract

This article provides a way to reduce the meal concentration of glucose in the blood in the blood, including the combination of an effective marine peptide and codonucleotide to the subject before or during meals. This amount is sufficient to reduce the trialGlucose concentration in blood.This article also provides a method of reducing the concentration of meals of the apertonin peptide in the blood of the subject, including the combination of an effective amount of marine peptide and fish nucleotide to the subject before dining or dining.Blood ingredients, wherein the combination is applied to the subject.

Description

technical field [0001] This article provides information on fish products and by-products and their uses in health, food, nutrition and medicine. Background technique [0002] Postprandial blood glucose (or blood glucose), together with associated hyperinsulinemia and lipemia, is implicated in the development of chronic metabolic diseases such as obesity, type 2 diabetes and cardiovascular disease. Evidence links postprandial blood glucose or blood glucose variability to the onset of these conditions or impairment of cognitive and exercise performance. [0003] Data show that pre-meal protein intake, when consumed with carbohydrates, lowers post-meal blood sugar; the blood sugar-lowering effect is particularly associated with dairy proteins such as whey protein. A recent study comparing whey protein with whey protein hydrolysates showed that whey protein consumed before a meal reduced food intake, postprandial blood glucose and insulin, and cumulative blood glucose and insu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/01A61P3/10A61P3/04A61P5/00A23L33/18A23L33/13A23L17/20A61K36/02A61K35/612A61K35/60
CPCA61K35/60A61K35/612A61K36/02A61K38/011A61K38/012A23V2002/00A23V2200/328A23V2250/1944A23V2250/5114A23V2250/54246A23V2250/543A23V2250/55A23L33/18A23L17/20A23L33/40A23L33/13A61P3/04A61P3/08A61P43/00A61P5/00A61P3/10A61K38/01A61K31/7052A23L33/30
Inventor O·伯珍E·莱德
Owner FIRMENICH SA