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Package system and method for inhibiting moisture entry

A packaging system and wrapping technology, applied in packaging, wrapping paper, transportation and packaging, etc., can solve the problems of expensive barrels and difficult for users to empty

Active Publication Date: 2017-05-17
AVANTOR PERFORMANCE MATERIALS LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the system has some disadvantages; the bucket is expensive and can be difficult for the user to empty

Method used

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  • Package system and method for inhibiting moisture entry
  • Package system and method for inhibiting moisture entry
  • Package system and method for inhibiting moisture entry

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Prototype test pouches were produced by heat sealing a multilayer pouch consisting of An inner layer made which provides a vapor transmission wall interposed between two outer layers made of substantially air and moisture impermeable HDPE. The top edges of the three layers are aligned and the inner The layer extends to a point intermediate the first and second ends of the two outer layers. The bottom and two side edges of the HDPE outer layer are sealed together to form the first compartment and The edges of the bottom and sides of the layer are sealed to the first outer HDPE layer to form a second compartment. Place 1kg of test salt in layer and place the desiccant material in the first compartment at the top of the pouch on the layer side In the second compartment on the other side of the deck (five 1 / 6 clay type desiccants from Desicare). Seal the edges of the three layers on the top side of the bag to close the system and place the The product on one sid...

Embodiment 2

[0071] Conduct laboratory studies to demonstrate the ability of the packaging system to maintain a free-flowing state of material. In addition, tests were performed to compare the packaging system with prior art disposable bags. A new packaging system bag was filled with 11.3 kg of free-flowing sodium chloride and the end cap, clamp and clip were placed on the bag. To another standard disposable bag that does not have a compartment for desiccant (i.e., Flowmor TMtechnique) filled with an equal amount of free-flowing sodium chloride and sealed in the same manner. The two bags were placed side by side in a stable room at 40°C and 75% RH. The two bags were tested after 32 days; sodium chloride in the packaging system (see Figure 12 photo) is free-flowing and lump-free. Said material in the prior art bag (see Figure 13 photo) clumps and is not free flowing.

Embodiment 3

[0073] The studies were carried out under high humidity conditions (40°C, 90% RH) in the bags to investigate the rate of moisture infusion into the bag walls. A bag with weighed 8 units of desiccant (approximately 8 oz) is placed in the stabilization chamber; the cap and collar are placed on the bag and sealed. After 96 hours, the desiccant had absorbed 6.5 grams of water, indicating that at this water vapor transmission rate, the desiccant would be exhausted within 30 days. Then place the bag in the bag (or any suitable bag with low water vapor transmission rate) and heat sealed. The water vapor transmission rate is significantly increased, and the test results show that the expected shelf life exceeds 400 days.

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Abstract

A package system for maintaining the physicochemical integrity of the contents of the package system that includes: an inner bag formed from a gas and / or moisture permeable material, an outer bag formed from an impermeable polymer material, a discharge port that provides access to the interior of the outer bag; and a desiccant or gas scavenging material. The first end of the outer bag sealingly surrounds the exterior wall of the discharge port. The second end of the inner bag is sealed closed and the desiccant or gas scavenging material is disposed in an isolated compartment. The second end of the outer bag is sealed closed to isolate the interior from the environment exterior to the package system.

Description

[0001] This application claims the benefit of priority to Provisional Application Serial No. 61 / 971,003, filed March 27, 2014, which is incorporated herein in its entirety. technical field [0002] The present invention is a packaging system that maintains the physicochemical integrity, free-flowing properties of its contents. In particular, the invention relates to packaging systems that prevent caking of salts used in the manufacture of biopharmaceuticals (eg, in the production of cell cultures). Background technique [0003] Various salts and buffers are used in manufacturing operations associated with biopharmaceutical production (eg, production of cell cultures and purification of proteins). These chemicals are dissolved under aseptic conditions to prepare various solutions. A common problem with delivering granular solids is that they have a tendency to agglomerate (ie, bind together into lumps) due to the presence of moisture in the solid. The moisture can come from...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B65D81/26
CPCB65D75/38B65D75/522B65D75/56B65D31/12B65D75/5872B65D2205/00B65D81/268B65D81/266B65D41/02B65D65/38
Inventor J.法里纳E.A.博莱萨N.德奥卡
Owner AVANTOR PERFORMANCE MATERIALS LLC