Carbon dioxide concentration-modified exhaled gas multi-component detection instrument and detection method

Abstract

The invention discloses a carbon dioxide concentration-corrected exhaled gas multi-component detection instrument and detection method. The detection instrument comprises a filter flask, a carrier gas pump, a drying pipe, a sampling gas pump, a sample ring, a first two-phase three-way solenoid valve, a second two-phase three-way solenoid valve, a third two-phase three-way solenoid valve, a chromatographic column and a detection gas chamber, and after communication, a sampling passage, a washing passage and a detection passage are respectively formed. The detection gas chamber is of a cuboid structure and is provided with a PCB tank, a MOS tank, a carbon dioxide sensor tank, a temperature measuring hole, a gas reaction chamber and the like. A sensor can quickly give a response and restore a baseline; after the outputted response is subjected to signal processing and calculation, hydrogen and methane concentrations are obtained and can be corrected according to carbon dioxide concentration, so that sample acquisition constraints are reduced, and the error caused by breath collection and other human factors is reduced. The carbon dioxide concentration-corrected exhaled gas multi-component detection instrument is perfect in functions, small in size, simple and convenient to operate, higher in accuracy, stability and repeatability and friendly in user interaction, and facilitates popularization of large-scale clinical application.

Description

technical field [0001] The invention relates to a trace mixed gas detection device and detection technology, in particular to an exhaled gas multi-component detector and detection method with carbon dioxide concentration correction. Background technique [0002] The hydrogen breath test has been widely used by experts in many fields around the world to diagnose carbohydrate malabsorption, small intestinal bacterial overgrowth and other diseases. Functional check method. Methanogens present in the small intestine can use hydrogen and carbon dioxide to produce methane, and a simple hydrogen breath test applied to such people will produce false negative results. Adding the determination of methane content in the hydrogen breath test will be more meaningful to eliminate false negative results and improve the diagnosis rate of related diseases. Methane and hydrogen breath testing is a simple, non-invasive, reproducible, and highly specific method for gastrointestinal function t...

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Problems solved by technology

[0006] In view of the problems existing in the prior art, the purpose of the present invention is to solve the shortcomings of the above-mentioned detection means, such as large instruments, complicated operation, long detection cycle, large error of detection results, unfriendly user interaction, short life, etc., and provide a carbon dioxide concentration correction method. , and can quickly and simultaneously detect methane, hydrogen and carbon dioxide, and is easy to operate, accuracy, stability, and repeatability all meet national standards, and is conducive to large-scale clinical application and promotion of small integrated detection instruments

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