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Beam shaping body for neutron capture therapy

A body shaping and neutron technology, which is applied in the field of beam shaping body for neutron capture therapy, and can solve the problems of poor treatment effect and normal tissue damage.

Active Publication Date: 2017-06-06
NEUBORON MEDTECH
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  • Summary
  • Abstract
  • Description
  • Claims
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Problems solved by technology

However, traditional photon or electron therapy is limited by the physical conditions of the radiation itself. While killing tumor cells, it will also cause damage to a large number of normal tissues along the beam path; in addition, due to the different sensitivity of tumor cells to radiation, traditional radiation therapy Treatment of more radiation-resistant malignancies (eg, glioblastoma multiforme, melanoma) is often less effective

Method used

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  • Beam shaping body for neutron capture therapy
  • Beam shaping body for neutron capture therapy
  • Beam shaping body for neutron capture therapy

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Embodiment Construction

[0027] The application of neutron capture therapy as an effective means of treating cancer has gradually increased in recent years, among which boron neutron capture therapy is the most common, and neutrons supplying boron neutron capture therapy can be supplied by nuclear reactors or accelerators. The embodiment of the present invention takes the accelerator boron neutron capture therapy as an example, and the basic components of the accelerator boron neutron capture therapy generally include an accelerator for accelerating charged particles (such as protons, deuterons, etc.), targets and heat removal System and beam shaper, in which the accelerated charged particles interact with the metal target to generate neutrons, according to the required neutron yield and energy, the available accelerated charged particle energy and current, and the physical and chemical properties of the metal target To select the appropriate nuclear reaction, the nuclear reactions that are often discu...

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Abstract

The invention, on one hand, provides a beam shaping body for neutron capture therapy, so as to improve the flux and the quality of a neutron source. The beam shaping body comprises a beam inlet, a target material, a retarding body adjacent to the target material, a reflector surrounding the retarding body, a thermal neutron absorber adjacent to the retarding body, a radiation shield arranged inside the beam shaping body and a beam outlet, wherein the target material and a proton beam incident from the beam inlet are subjected to a nuclear reaction to produce neutrons; the neutrons form a neutron beam; the neutron beam limits a spindle; the retarding body retards the neutrons generated from the target material to an epithermal neutron energy region; the retarding body is set to be in a shape containing at least one cone; the retarding body comprises a main body part and a supplementary part surrounding the periphery of the main body part; the material of the supplementary part is different from that of the main body part; the reflector guides neutrons deviating from the spindle back to the spindle to improve the epithermal neutron beam intensity; the thermal neutron absorber is used for absorbing thermal neutrons to avoid over dose with superficial normal tissues in the case of therapy; and the radiation shield is used for shielding leaked neutrons and photons to reduce the normal tissue dose in a non-radiation area.

Description

technical field [0001] The invention relates to a beam shaping body, in particular to a beam shaping body for neutron capture therapy. Background technique [0002] With the development of atomic science, radiation therapy such as cobalt 60, linear accelerator, and electron beam has become one of the main means of cancer treatment. However, traditional photon or electron therapy is limited by the physical conditions of the radiation itself. While killing tumor cells, it will also cause damage to a large number of normal tissues along the beam path; in addition, due to the different sensitivity of tumor cells to radiation, traditional radiation therapy Treatment for more radioresistant malignant tumors (eg glioblastoma multiforme, melanoma) is often less effective. [0003] In order to reduce radiation damage to normal tissues around the tumor, the concept of target therapy in chemotherapy (chemotherapy) has been applied to radiation therapy; and for tumor cells with high ra...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/10
CPCA61N5/1042A61N5/1077Y02E30/10
Inventor 刘渊豪陈韦霖李珮仪
Owner NEUBORON MEDTECH
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