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Clinical nutrition agent for hepatopathy and application thereof

A nutrient and liver disease technology, applied in the medical and health field, can solve the problems of aggravating liver function damage, reducing the quality of life of patients with liver cirrhosis, and malabsorption, so as to benefit liver cell regeneration, protect existing liver function, and improve metabolic disorders Effect

Inactive Publication Date: 2017-06-13
THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, patients are prone to loss of appetite and malabsorption due to impaired liver function, which not only increases the possibility of nutritional deficiencies, but also aggravates liver function damage and reduces the quality of life of patients with liver cirrhosis, thus falling into a vicious circle
This severe liver damage can lead to metabolic disorders of macronutrients and micronutrients in the body, resulting in nutritional deficiencies in patients with liver cirrhosis

Method used

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  • Clinical nutrition agent for hepatopathy and application thereof
  • Clinical nutrition agent for hepatopathy and application thereof
  • Clinical nutrition agent for hepatopathy and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] In the clinical nutrient for liver disease in Example 1, the protein energy supply component, the fat energy supply component and the sugar energy supply component account for 20%, 20% and 60% of the energy supply respectively.

[0025] Specifically, the liver disease clinical nutrient in Example 1 is mainly composed of the following components: 25.5g maltodextrin, 30g enzymatic rice flour, 8.9g medium-chain fatty acid, 0.7g long-chain fatty acid, 20g branched-chain amino acid, 2g soybean isolate Protein, 1g whey protein, 8g dietary fiber, 1g fat-soluble vitamin, 2g water-soluble vitamin and 1g trace element. The iron and copper in the trace elements are half of the dosage of conventional nutritional supplements for liver diseases, and the dosage of sodium is 75% of that of conventional nutritional supplements for liver diseases.

[0026] In a preferred embodiment of Example 1, 20 g of branched chain amino acids consists of 6 g of arginine, 7 g of ornithine and 7 g of a...

Embodiment 2

[0028] In the clinical nutrient for liver disease in Example 2, the protein energy supply component, the fat energy supply component and the sugar energy supply component accounted for 17%, 18.5% and 64.5% of the energy supply respectively.

[0029] Specifically, the liver disease clinical nutrient in Example 2 is mainly composed of the following components: 30g maltodextrin, 34.5g enzymatic rice flour, 8.2g medium-chain fatty acid, 17g branched-chain amino acid, 2g soybean protein isolate, 1g whey protein , 8g dietary fiber, 1g fat-soluble vitamins, 2g water-soluble vitamins and 1g trace elements.

Embodiment 3

[0031] The clinical nutrient for liver disease in Example 3 is mainly composed of the following components: 30g maltodextrin, 34.5g rice flour, 8.2g medium-chain fatty acid, 17g branched-chain amino acid, 8g dietary fiber, 1g fat-soluble vitamin, 2g water-soluble vitamin and 1g trace elements.

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Abstract

The invention belongs to the field of medical and health care, and specifically provides a clinical nutrient for liver diseases. The liver disease clinical nutrient includes protein energy supply components, fat energy supply components and sugar energy supply components, and the energy supply ratio of the three is 17-20:18.5-20:60-64.5. At the same time, the present invention also provides the application of the liver disease clinical nutritional agent of the present invention in the preparation of a composition for treating liver diseases. The beneficial effect achieved is that the clinical nutritional agent for liver disease of the present invention can provide a pretreatment nutritional substrate that meets the special needs of liver disease through targeted nutritional formula adjustment. Reduce the burden on the liver, improve metabolic disorders, protect the existing liver function, and benefit the regeneration of liver cells. Then it can meet the continuous medium and high consumption energy demand of patients with chronic liver disease for long-term treatment, and provide the necessary and key nutritional guarantee for the reconstruction and long-term maintenance of liver-intestinal function.

Description

technical field [0001] The invention belongs to the field of medical and health care, and in particular relates to a nutritional agent for clinical liver disease and its application. Background technique [0002] my country is an area with a high incidence of viral hepatitis. About 3% of patients with chronic hepatitis B develop decompensated liver cirrhosis every year, and the cumulative incidence rate in 5 years is about 16%. The 5-year mortality rate of compensated liver cirrhosis is 14%-20%, and the 5-year mortality rate of decompensated liver cirrhosis is 70%-86%. According to the above, hepatitis B cirrhosis has become a major disease that endangers the lives and health of the people in our country, and has brought heavy economic and psychological burdens to patients, families and the entire country. [0003] Studies have confirmed that 60%-100% of patients with liver cirrhosis suffer from malnutrition in varying degrees, and malnutrition also affects the clinical out...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/17A61P1/16A61P3/02A61K31/718A61K36/899A61K31/19A61K31/20A61K31/198A61K36/48A61K38/16A61K35/20A61K31/715A61K33/26A61K33/34A61K33/00
CPCA61K38/1709A61K31/19A61K31/198A61K31/20A61K31/715A61K31/718A61K33/00A61K33/26A61K33/34A61K35/20A61K36/48A61K36/899A61K38/168
Inventor 张大志
Owner THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIV
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