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A kind of compound phellodendron gel for treating children's eczema and preparation method thereof

A technology of compound phellodendron and phellodendron, which is applied in the field of medicine, can solve the problems of insufficient curative effect, short retention time of wounds, secondary infection, etc., and achieve the effects of prolonging the retention time of drugs, long duration of drug effects, and not polluting clothes

Active Publication Date: 2020-06-16
SHANDONG HANFANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the dosage form of compound Phellodendron phellodendron liquid varnish is mainly external liquid preparation, which has a short residence time on the wound surface and cannot give full play to the curative effect. In clinical practice, sterile gauze is used for wet compress, which is inconvenient to use and easily causes secondary infection

Method used

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  • A kind of compound phellodendron gel for treating children's eczema and preparation method thereof
  • A kind of compound phellodendron gel for treating children's eczema and preparation method thereof
  • A kind of compound phellodendron gel for treating children's eczema and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0078] 1. Product: a compound Phellodendron gel for treating eczema in children

[0079] 2. Materials and methods

[0080] 2.1 Instrument

[0081] pH meter, electric constant temperature water bath, refrigerator, oven, electronic balance, etc.

[0082] 2.2 Materials and reagents

[0083] Forsythia: It is the dried fruit of Forsythia suspensa (Thunb.) Vahl, a plant of Oleaceae.

[0084] Phellodendron: It is the dry bark of the Rutaceae Phellodendron chinense Schneid.

[0085] Honeysuckle: It is the dry flower bud or the first flower of Lonicera japonica Thunb.

[0086] Dandelion: the dried whole herb of Taraxacum mongolicum Hand.-Mazz., Taraxacum borealisinense Kitam. or several plants of the same genus

[0087] Centipede: It is the dry body of Scolopendra subspinipes mutilans L. Koch, a centipede animal with few spines.

[0088] The above-mentioned medicinal materials are in compliance with the provisions of each medicinal material in the first part of the "Chinese Pharm...

Embodiment 2

[0146] Formula: 70 parts of Forsythia, 35 parts of Cortex Phellodendri, 35 parts of Honeysuckle, 35 parts of Dandelion, 2.1 parts of Centipede, 1 part of Carbomer, 5 parts of Transcutol P.

[0147] Preparation:

[0148] (1) Take the five flavors of traditional Chinese medicines in the prescription by weight components, add water to decoct and extract three times, the first time is 1 hour, the second time is 45 minutes, and the third time is 30 minutes;

[0149] (2) The decoctions are combined, filtered, and the filtrate is concentrated to a clear paste with a relative density of 1.10 to 1.15 (measured at a temperature of 50°C);

[0150] (3) Add ethanol to make the ethanol content reach 70%, let it stand for 24 hours, filter, and concentrate the filtrate under reduced pressure until there is no alcohol smell, and the compound Phellodendron Phellodendri extract is obtained after alcohol precipitation.

[0151] (4) Take the liquid extract after alcohol precipitation, add 4 times...

Embodiment 3

[0156] Formula: 80 parts of Forsythia, 40 parts of Cortex Phellodendri, 40 parts of Honeysuckle, 40 parts of Dandelion, 2.4 parts of Centipede, 3 parts of Carbomer, 10 parts of Transcutol P.

[0157] The preparation method is the same as in Example 2.

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Abstract

The invention provides compound Cortex Phellodendri gel for treating child eczema and a preparation method. The compound Cortex Phellodendri gel for treating child eczema consists of the following raw herbal medicines in parts by weight: 70-90 parts of Fructus Forsythiae, 35-45 parts of Cortex Phellodendri, 35-45 parts of honeysuckle, 35-45 parts of dandelion, 2.1-2.7 parts of Scolopendra, 1-6 parts of carbomer, 5-15 parts of Transcutol P, 2-5 parts of triethanolamine, 10-30 parts of glycerol and 0.1-0.5 part of potassium sorbate. By the compound Cortex Phellodendri gel, the shortcomings that the residence time of compound Cortex Phellodendri liquid liniment on wound is short, and the wound needs to be covered with gauze can be overcome to a great extent; compared with other domestic and international like products, the compound Cortex Phellodendri gel has considerable resource advantages and technical advantages; and used Chinese herbal medicines are common medicinal materials, auxiliary materials are common pharmaceutic adjuvants, and the supply quality can be guaranteed. The traditional Chinese medicine extracting technology is mainly used, and is organically combined to an alcohol precipitation and water precipitation separation technology, a gel preparation process and the like, effective ingredients of traditional Chinese medicines and the pharmaceutic adjuvants are combined organically, and the efficacy is played fully. The compound Cortex Phellodendri gel for treating child eczema has considerable social benefit and economic benefit.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a compound cortex cortex gel for treating children's eczema and a preparation method thereof. Background technique [0002] Children are a special group in the crowd. They are in the stage of gradual growth and development to maturity. They are divided into 8 different stages because of their different ages. However, children with different ages have different frequently-occurring diseases, and children's skin diseases are different from those of adults. features. In our country, the eugenics policy is implemented, parents are encouraged to have only one child, and they are more concerned about children. Children's skin and children's skin diseases are gradually paid attention to. Children's eczema and atopic dermatitis are common chronic, inflammatory diseases in children. sexual skin disease. With the development of my country's national economy and the improvement of indu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/06A61K36/756A61K47/32A61K47/10A61K47/18A61P17/00A61K35/648
CPCA61K9/06A61K35/648A61K36/288A61K36/355A61K36/634A61K36/756A61K47/10A61K47/18A61K47/32A61K2236/331A61K2236/51A61K2236/53A61K2300/00
Inventor 秦承雪
Owner SHANDONG HANFANG PHARMA