Unlock instant, AI-driven research and patent intelligence for your innovation.

Medicine with anti-ageing activity

An anti-aging and drug technology, applied in the field of biomedicine, can solve the problems of increasing kidney damage, gastrointestinal dysfunction, cardiovascular diseases, etc.

Inactive Publication Date: 2017-11-24
SICHUAN AGRI UNIV
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention provides a drug with anti-aging activity, which solves the problem of increasing kidney damage, gastrointestinal dysfunction and cardiovascular disease in the prior art due to the inhibitory activity of celecoxib on COX-2 in clinical practice for a long time. risk technical issues

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medicine with anti-ageing activity
  • Medicine with anti-ageing activity
  • Medicine with anti-ageing activity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0016] In order to make the above objects, features and advantages of the present invention more comprehensible, the present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0017] The invention provides a medicine with anti-aging activity, comprising: 2,5-dimethylcelecoxib, 2,5-dimethylcelecoxib (2,5-Dimethyl-celecoxib, DMC) is A derivative of celecoxib, the chemical structure of 2,5-dimethylcelecoxib is as follows figure 1 shown.

[0018] Wherein, the drug is any one of oral, injection or topical dosage form.

[0019] The invention provides a medicine with anti-aging activity, which comprises: 2,5-dimethylcelecoxib, which is a derivative of celecoxib. The invention can remarkably prolong the life span of females and males. Improve aging-related physiological indicators, improve intestinal health, and enhance tolerance to stress.

[0020] In order to verify the effect of DMC on lifespan in the em...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the field of medicines and discloses a medicine with the anti-ageing activity and a preparation method. The medicine comprises 2,5-dimethylcelecoxib, wherein the 2,5-dimethylcelecoxib is a derivative of celecoxib. According to the medicine, the life of females and the males can be remarkably prolonged, related physiological indexes of aging are improved, the health level of intestine is improved, and the pressure tolerance is enhanced.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a medicine with anti-aging activity. Background technique [0002] Drug anti-aging is a major topic in the field of aging and anti-aging research. There have been a large number of literature reports on anti-aging drugs and compounds. However, there are not many anti-aging drugs with clear mechanism of action and few side effects, so finding new compounds with anti-aging activity and studying their mechanism of action are still a hotspot in aging biology. Among them, the secondary development of some FDA-approved drugs is a shortcut to study this issue. [0003] The non-steroidal drug celecoxib is a commonly used anti-inflammatory drug approved by the FDA. In addition to its anti-inflammatory and analgesic effects, previous studies have shown that it can also prolong the lifespan of nematodes by inhibiting the insulin signaling pathway. However, due to the inhibitory activity of cele...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/635A61K47/69A61P39/00A61P1/00
CPCA61K31/635
Inventor 吴奇杨明耀樊晓兰
Owner SICHUAN AGRI UNIV
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More