Submucosal injection solution

Abstract

The invention provides a submucosal injection solution. The submucosal injection solution comprises, by weight, 0.1-3.0 parts of sodium hyaluronate, 0.001-0.02 parts of coloring agent and 90-99 parts of water. The dyeing agent is one or more of indigo carmine, toluidine blue, phenol red, Congo red and crystal violet. The submucosal injection solution has good fluidity and a long swelling effect, and the sodium hyaluronate can serve as a mechanical barrier. The lubricating effect is good, and friction caused by foreign matters in the esophagus, stomach and intestinal tract during wound healing can be reduced. Local inflammatory response and infiltration of inflammatory cells can be reduced, and bleeding and errhysis can be reduced and inhibited. A protective film is formed on the serosa and retained for a long time, so that the serosa covering the surface of an organ can be better repaired. By affecting the viability of immune cells and cytokines, the immune regulatory function is realized, and the submucosal injection solution has angiogenesis and wound healing promoting, anti-tumor, immune regulation and other physiological functions.

Description

technical field [0001] The invention relates to a submucosal injection solution. Background technique [0002] Endoscopic submucosal dissection (Endoscopic submucosal dissection, ESD) is developed by Japanese scholars in the 1990s on the basis of endoscopic mucosal resection (EMR), which integrates the diagnosis and treatment of early gastric cancer. Endoscopic techniques. Studies have shown that compared with traditional laparotomy, endoscopic treatment has a high one-time tumor resection rate, and can effectively avoid complications such as incision infection, incision dehiscence, and dumping syndrome. It has significant advantages in alleviating the suffering of patients during treatment and improving the quality of life of patients, which fully embodies the advantages of minimally invasive. At the same time, ESD can also obtain complete pathological specimens, which is of great significance for diagnosing the development stage of tumors and preventing recurrence. [0...

AI Technical Summary

Problems solved by technology

However, it is worth noting that when the electric cutting and coagulation mode is used to strip the submucosal tissue during the ESD process, the smoke generated by the ionization of glycerol and fructose seriously interferes with the endoscopic field and affects the smooth progress of the operation.

[0007] Patent application number: 201280052159.7 discloses a submucosal swelling agent, by using xanthan gum, carrageenan, gellan gum