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Compositions capable of alleviating alcohol-induced chemical liver injury

A technology for chemical liver injury and composition, applied in the field of pharmaceutical preparations, can solve the problems of decreased drug efficacy, impact on liver protection, instability and the like

Active Publication Date: 2018-02-09
WEIHAI BAIHE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many liver-protecting products. The active ingredients of liver-protecting products mainly include: total flavonoids in Chinese herbal medicines, crude polysaccharides, puerarin, schisandrin A, silibinin, etc., and most of these traditional Chinese medicines are unstable. Efficacy declines, affecting liver protection

Method used

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  • Compositions capable of alleviating alcohol-induced chemical liver injury
  • Compositions capable of alleviating alcohol-induced chemical liver injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A composition for alleviating chemical liver damage caused by alcohol, comprising 33.3 parts by weight of milk thistle extract, 13 parts by weight of Schisandra chinensis extract, 20 parts by weight of dandelion extract, 10 parts by weight of Haematococcus powder and 22.7 parts by weight of carboxymethyl cellulose. The composition is mixed, wetted by adding a small amount of ethanol, dried and sieved to obtain composition granules.

Embodiment 2

[0026] The difference between the present embodiment and Example 1 is that the composition includes 35 parts by weight of milk thistle extract, 15 parts by weight of Schisandra chinensis extract, 25 parts by weight of dandelion extract, 12 parts by weight of pluvialis Algae powder and 25 parts by weight of carboxymethyl cellulose.

Embodiment 3

[0028] The difference between this embodiment and Example 1 is that the composition includes 30 parts by weight of milk thistle extract, 10 parts by weight of Schisandra chinensis extract, 17 parts by weight of dandelion extract, and 7 parts by weight of Plus cerevisiae Algae powder and 20 parts by weight of carboxymethyl cellulose.

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Abstract

The present invention discloses a composition capable of alleviating alcohol-induced chemical liver injury, which comprises the following components in parts by weight: 30-35 parts of a silybum marianum extract, 10-15 parts of a schisandra chinensis extract, 17-25 parts of a dandelion extract, 7-12 parts of haematococcus pluvialis powder, and 20-25 parts of carboxymethyl cellulose. The compositionof the present invention has the advantages of scientific cooperation, significant protective effect and stable pharmacological effect. The animal experiment proves that the composition has certain protective effect on ethanol-induced acute liver injury.

Description

technical field [0001] The present invention relates to a pharmaceutical preparation of undetermined structure from traditional herbal medicines of algae and plants, especially a composition for alleviating chemical liver injury caused by alcohol. Background technique [0002] Chemical liver injury is liver injury caused by chemical hepatotoxic substances. These chemicals include alcohol, toxic chemicals in the environment, and certain drugs. With the development of my country's economy and the improvement of people's living standards, the incidence of chemical liver injury is increasing year by year, seriously affecting the health of Chinese people. At present, there are many liver-protecting products. The active ingredients of liver-protecting products mainly include: total flavonoids, crude polysaccharides, puerarin, schisandrin A, silibinin, etc. in Chinese herbal medicines. Most of these traditional Chinese medicines are unstable. Efficacy decreased, affecting the liv...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/79A61K36/57A61K9/16A61P1/16
CPCA61K9/1652A61K36/05A61K36/28A61K36/288A61K36/57A61K36/79A61K2236/33A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 肖水水张伟李艳王丽娜
Owner WEIHAI BAIHE BIOTECH
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