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A traditional Chinese medicine compound transdermal agent for treating animal foot rot and preparation method thereof

A technology of foot rot and transdermal agent, which is applied in the field of traditional Chinese medicine compound transdermal agent for the treatment of animal foot rot and its preparation, can solve the problems of single, poor curative effect, inconvenient medication, etc., and achieve convenient use, convenient medication, Facilitate the effect of long-term treatment

Active Publication Date: 2021-03-12
河南大农联生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The object of the present invention is to provide a traditional Chinese medicine compound transdermal agent for treating animal foot rot, so as to solve the problems of relatively single drug for the treatment of foot rot, inconvenient medication, and poor curative effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A traditional Chinese medicine compound transdermal agent for treating animal foot rot, which is made of the following components in parts by weight: 60 parts of Clematis clematis, 60 parts of Houttuynia cordata, 40 parts of safflower, 20 parts of frankincense, and 20 parts of myrrh parts, the total amount is 500g.

[0021] The method for preparing the above-mentioned traditional Chinese medicine compound transdermal agent for treating animal foot rot includes the following steps: (1) take each Chinese medicine and add 8 times the total amount of medicinal materials to soak for 2 hours, decoct three times, respectively for 2 hours and 2 hours. hour and 1 hour, combine the filtrate three times, and concentrate the filtrate to a relative density of 1.20 by rotary evaporation; (2) Add 4 times the amount of 95% ethanol to the solution prepared in (1), stir and mix well, refrigerate overnight, and recover the supernatant After ethanol, repeat alcohol precipitation and recove...

Embodiment 2

[0023] A traditional Chinese medicine compound transdermal agent for treating animal foot rot, which is made of the following components by weight: 50 parts of Clematis clematis, 50 parts of Houttuynia cordata, 30 parts of safflower, 15 parts of frankincense, and 15 parts of myrrh parts, the total amount is 500g.

[0024] The method for preparing the above-mentioned traditional Chinese medicine compound transdermal agent for treating animal foot rot includes the following steps: (1) take each Chinese medicine and add 7 times the total amount of medicinal materials to soak for 2 hours, decoct three times, respectively for 2 hours, 2 hours, and 2 hours. hour and 1 hour, combine the filtrate three times, and concentrate the filtrate by rotary evaporation to a relative density of 1.15; (2) add 4 times the amount of 95% ethanol to the solution prepared in (1), stir and mix well, refrigerate overnight, and recover the supernatant After ethanol, repeat alcohol precipitation and recov...

Embodiment 3

[0026] A traditional Chinese medicine compound transdermal agent for treating animal foot rot, which is made of the following components in parts by weight: 40 parts of Clematis clematis, 40 parts of Houttuynia cordata, 20 parts of safflower, 10 parts of frankincense, and 10 parts of myrrh parts, the total amount is 500g.

[0027] The method for preparing the above-mentioned traditional Chinese medicine compound transdermal agent for treating animal foot rot includes the following steps: (1) take each Chinese medicine and add 6 times the total amount of medicinal materials, soak in water for 2 hours, and decoct three times, respectively for 2 hours, 2 hours, and 2 hours. hour and 1 hour, combine the filtrate three times, concentrate the filtrate by rotary evaporation to a relative density of 1.10; (2) add 4 times the amount of 95% ethanol to the solution prepared in (1), stir and mix well, refrigerate overnight, and recover the supernatant After ethanol, repeat alcohol precipi...

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Abstract

The invention belongs to the technical field of veterinary medicine preparations, and in particular relates to a traditional Chinese medicine compound transdermal agent for treating animal foot rot and a preparation method thereof. The traditional Chinese medicine compound transdermal agent for treating animal foot rot is made of the following components by weight: 30-70 parts of Clematis clematis, 30-70 parts of Houttuynia cordata, 10-50 parts of safflower, 5-30 parts of frankincense part, 5-30 parts of myrrh, and 1-15 parts of a transdermal enhancer are also included in the raw material components, and the transdermal enhancer is decyl methyl sulfoxide and azone. The traditional Chinese medicine compound transdermal agent for treating foot rot in animals provided by the present invention can avoid the first-pass effect of the liver on the one hand and has high bioavailability; The drug can more effectively act on the diseased part of the animal, the drug release rate is stable, the toxic and side effects are small, the drug is convenient, and it is beneficial to long-term treatment.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine preparations, and in particular relates to a traditional Chinese medicine compound transdermal agent for treating animal foot rot and a preparation method thereof. Background technique [0002] Foot rot is also called inter-hoof rot or inter-toe rot. It is easy to develop in autumn. It is an infectious disease that can occur in sheep, cattle, pigs, and horses. Purulent discharge. It is characterized by local tissue inflammation and necrosis. Because the disease often affects the hoof, it is called "foot rot". The disease occurs all over my country, especially in the vast pastoral areas of Northwest China, which is endemic and very harmful to the development of animals. Foot rot is one of the important diseases affecting animal production, and it shows a high incidence rate in all parts of our country. The high incidence rate can reach 30-40% in house-fed cattle. The occurrence of ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/78A61P31/04
CPCA61K36/286A61K36/324A61K36/328A61K36/716A61K36/78A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 刘森涛邢永魁韩文拴王丽景
Owner 河南大农联生物工程有限公司
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