Tofogliflozin composition
A technology of toggliflozin and composition, which is applied in the field of toggliflozin tablet composition, can solve the problems of high related substances, low dissolution rate of preparations, etc. Effect
Inactive Publication Date: 2018-03-20
WEIHAI GUANBIAO INFORMATION TECH
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Abstract
The invention relates to a torgliflozin tablet composition and belongs to the technical field of pharmaceutical preparations. The torgliflozin tablet composition in a unit dose comprises 5 mg of torgliflozin, 65 to 80 mg of lactose, 0.8 to 1.5 mg of sodium lauryl sulfate, 10 to 20 mg of calcium sulfate, 8-15mg of fumed silica, 8-16mg of beta-cyclodextrin, 4-8mg of povidone K30, 4-8mg of cross-linked povidone and 1-1.5mg of magnesium stearate. The stable torgliflozin tablet composition has excellent dissolution rate, and the dissolution rate and the content of related substances are stable during the effective period. The problems of decline in the dissolution rate and raise of the content of the related substances in the tablet storage process in the prior art can be solved.
Application Domain
Metabolism disorderInorganic non-active ingredients +3
Technology Topic
Magnesium stearatePharmaceutical formulation +10
Examples
- Experimental program(3)
- Comparison scheme(2)
- Effect test(2)
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