Novel lavage fluid preparation

The technology of lavage solution and preparation is applied in the field of medicine and medicine, which can solve the problems of no sterilization function and single function, and achieve the effects of excellent inhibition effect, wide application and broad application prospect.

Inactive Publication Date: 2018-03-23
李雪红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The function is relatively single, and it does not have the function of sterilization

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A new type of lavage fluid preparation, which consists of the following components according to mass percentage: 4.8% sodium hyaluronate, 4.0% povidone iodine, 9.5% nonoxynol, 3.8% chitosan, and 58.0% phosphate buffer , and the balance is water.

Embodiment 2

[0020] A new type of lavage fluid preparation, which is composed of the following components according to mass percentage: sodium hyaluronate 5.8%, povidone iodine 4.5%, nonoxynol 8.5%, chitosan 3.8%, phosphate buffer 50.0% , and the balance is water.

Embodiment 3

[0022] A new type of lavage fluid preparation, which consists of the following components according to mass percentage: sodium hyaluronate 4.5%, povidone iodine 4.0%, nonoxynol 10.0%, chitosan 3.8%, phosphate buffer 65.0% , and the balance is water.

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PUM

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Abstract

The invention relates to a novel lavage solution preparation, which is composed of the following components in mass percentage: 3.5-6.2% of sodium hyaluronate, 2.0-5.0% of povidone-iodine, 8.0-12.5% ​​of nonoxynol, and 3.2% of chitosan ‑5.0%, phosphate buffer 50.0‑75.0%, and the balance is water. The inventor conducted a large number of screening experiments on components and dosages in the early stage, and unexpectedly found that the technical solution of the present invention can effectively prevent the form of tissue adhesion, promote wound healing and can It can effectively stop bleeding, and can also play a role in sterilization, and has an excellent inhibitory effect on microorganisms. It is widely used in ophthalmology, surgery, abdominal chemotherapy and other operations, and has broad application prospects.

Description

technical field [0001] The invention belongs to the technical field of medicine and medicine, and in particular relates to a novel lavage solution preparation. Background technique [0002] Adhesions are abnormal structures in which fibrous bands of connective tissue join together with adjacent tissues or organs. Postoperative tissue adhesions are one of the most serious postoperative complications resulting from surgical procedures. At present, in the clinical treatment process, the lavage fluid can prevent postoperative tissue adhesion during the treatment process. How to effectively prevent the form of tissue adhesion after the operation, without affecting the healing of the incision, and effectively stop the bleeding, while inhibiting the production of microorganisms, has become the most urgent problem to be solved in clinical medicine. [0003] Lavage solution is the most important agent in clinical medicine, although it can solve the above problems, it also has some p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/722A61K31/79A61K31/728A61K31/085A61K9/08A61P31/02A61P17/02A61P31/04A61P31/10
CPCA61K31/722A61K9/08A61K31/085A61K31/728A61K31/79A61K2300/00
Inventor 李雪红
Owner 李雪红
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