Statistical calculation method for detecting publication bias based on arctangent transformation
A statistical calculation and arctangent technology, applied in the field of evidence-based medicine, it can solve the problems of incomplete data and use restrictions, and achieve the effect of high test efficiency and easy realization.
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[0011] Below in conjunction with specific embodiment and appended figure 1 The present invention is further described. figure 1 is a flow chart of the method of the present invention. The specific process is as follows:
[0012] Step 1: Take the most commonly used OR value in epidemiological research as the effect index. A 2 × 2 table for a single case-control study follows.
[0013]
case group
control group
total
exposed
a
b
M 1
non exposed
c
d
M 2
total
N t
N c
n
[0014] a and b are the number of events in the case and control groups, respectively, and c and d are the number of non-events in the case and control groups, respectively. Nt and Nc are the total number of cases and controls, respectively, and n is the sample size of a single study. The estimated logOR of the effect size is
[0015]
[0016] The estimated variance is
[0017]
[0018] Step 2: After performing arctangent tra...
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