A method for three-dimensional printing artificial skin

A kind of artificial skin, 3D printing technology, applied in the direction of skin transplantation, biomaterial sampling method, epidermal cells/skin cells, etc., can solve the problems of artificial skin loss of perspiration and hair follicle protection, inability to obtain skin sweat glands and hair follicles, etc. To achieve the effect of sterile biocompatibility

Active Publication Date: 2018-04-24
3D GLOBAL BIOTECH
View PDF9 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, no matter whether the artificial skin obtained from mammals or the artificial skin shaped by polymer materials cannot obtain the original sweat glands and hair follicles of the skin, the artificial skin lo

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A method for three-dimensional printing artificial skin
  • A method for three-dimensional printing artificial skin
  • A method for three-dimensional printing artificial skin

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0030] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below with reference to the accompanying drawings and examples.

[0031] see figure 1 , figure 1 It is a flow chart illustrating the steps of a specific embodiment of the method for 3D printing artificial skin of the present invention. In one embodiment of the present invention, the method for 3D printing artificial skin of the present invention, it comprises the following steps: S 1 : Mix autologous dermal cells and hydrogel material 21 and print dermis layer 14, S 2 : mix autologous keratinocytes and hydrocolloid material 22 and print epidermis 16 on dermis 14, S 3 : The sweat gland and hair follicle precursor cells 23 are implanted and printed to the dermis 14 via the epidermis 16 to produce artificial skin.

[0032] Wherein, the autologous dermal cells, autologous keratinocytes, and sweat gland and hair follic...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Thicknessaaaaaaaaaa
Thicknessaaaaaaaaaa
Login to view more

Abstract

The present invention discloses a method for three dimensional printing artificial skin. The method comprises the following steps of: printing a dermis layer by a hydrogel combined with an autologousdermal cell; printing an epidermis layer on the dermis layer by a hydrogel combined with an autologous kerationocytes cell; and implanting a plurality of progenitor cells for sweat glands and hair follicles through the epidermis layer into the dermis layer to form an artificial skin. Because all used materials are from the autologous skin, and the 3D printing technology is used to implant the progenitor cells for sweat glands and hair follicles to form the artificial skin which has sweat glands and hair follicles. According to the method, an artificial skin with a complete skin structure is completed.

Description

technical field [0001] The present invention relates to a method of preparing artificial skin, and in particular, to a method of 3D printing artificial skin with sweat glands and hair follicles. Background technique [0002] The skin is the largest tissue structure of the human body. It not only has the functions of regulating body temperature and preventing water loss in the human body, but also is the first line of defense for the human body to defend against external pathogens and bacterial infections. So whenever there is extensive damage to the skin, the body is at risk of dehydration and death from bacterial infection. [0003] There are several ways to traditionally treat skin damage that cannot heal naturally: take a piece of skin from another part of the patient's body and put it on the wound; or take skin from other humans or mammals (such as pigs) and put it on the wound . The former cannot obtain a large amount of skin, otherwise it is easy to cause bacterial i...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61L27/60A61L27/38A61L27/50B33Y10/00B33Y70/00
CPCB33Y10/00B33Y70/00A61L27/3804A61L27/3813A61L27/3886A61L27/50A61L27/60C12M33/00A61L27/52B33Y80/00A61F2/105C12M21/08A61L27/24C09D11/108C12N2502/094
Inventor 欧耿良游志华詹育豪郑为仁
Owner 3D GLOBAL BIOTECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap