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Novel chalcone compound and application thereof

A technology of compound and composition, applied in the field of chemical structure of novel chalcone compounds

Pending Publication Date: 2018-05-01
王艳艳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there is no research report on chalcones that exert anti-aging effects from multiple levels. The inventors have designed and synthesized a series of novel chalcones through long-term and arduous research experiments, and finally obtained a series of novel chalcones, which have been tested for pharmacological activity. They were found to have good anti-aging benefits

Method used

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  • Novel chalcone compound and application thereof
  • Novel chalcone compound and application thereof
  • Novel chalcone compound and application thereof

Examples

Experimental program
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Effect test

Embodiment Construction

[0015] 1. Research on the anti-aging effect and mechanism of compound A102 on aging female mice

[0016] Sample: Compound A102

[0017] Positive control drug: Vit-E

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Abstract

The invention provides a novel 2-propene-1-one substituted chalcone compound with an anti-aging effect. The novel chalcone compound can serve as a bulk drug for preparing related drugs with anti-oxidation and anti-aging functions of various dosage forms, and has the medical application of treating aging-related diseases.

Description

technical field [0001] The invention belongs to the field of medicinal chemistry, in particular, the invention relates to the chemical structure of novel chalcone compounds with anti-aging effect. In addition, the present invention also relates to the anti-aging and anti-oxidation mechanism and application of the compound. Background technique [0002] The problem of aging is considered to be one of the three major worldwide social problems in the 21st century. As of the end of 2016, my country has already had an aging population of more than 100 million. By 2050, my country's aging population will account for a quarter of the total population. Aging is a process of programmed decline of various tissues and organs in organisms starting from the cellular level with age. It is a common phenomenon in organisms. Aging is divided into two types: physiological aging (normal aging) and pathological aging (abnormal aging). Types of. Current studies believe that aging and geriatri...

Claims

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Application Information

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IPC IPC(8): C07C49/84A61K31/12A61P39/06
CPCC07C49/84
Inventor 王艳艳
Owner 王艳艳
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