Processing method for improving drug effect of tendril-leaved fritillary bulb powder and product and use

A kind of Chuanbei powder, Chuanbei technology, applied in non-active ingredients medical preparations, medical preparations containing active ingredients, pharmaceutical formulas and other directions, can solve the problems of loss of effective substances, long production cycle, easy residues, etc. Increased solubility, improved efficiency, uniform color effects

Inactive Publication Date: 2018-05-11
四川德仁堂中药科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method is simple in process and easy to operate, but it is not mild, and it is easy to cause the loss of effective substances, and some harmful substances such as pesticide residues and heavy metals are also easy to remain, which is potentially harmful to the human body, and the production cycle is longer.

Method used

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  • Processing method for improving drug effect of tendril-leaved fritillary bulb powder and product and use
  • Processing method for improving drug effect of tendril-leaved fritillary bulb powder and product and use
  • Processing method for improving drug effect of tendril-leaved fritillary bulb powder and product and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] The processing of embodiment 1 Chuanbei powder

[0047] (1) Cleaning:

[0048] Wash and drain the excavated fresh Chuanbei; chop it;

[0049] (2) Add compound antioxidant protection agent:

[0050] Add 0.7% of its weight to the chopped fresh Chuanbei granule, which is composed of Vc, Vc sodium, Vc phosphate and tea polyphenols; the composite antioxidant protection agent consists of Vc, Vc sodium , Vc phosphate and tea polyphenols are composed in a weight ratio of 5:4:3:5;

[0051] (3) Coarse crushing:

[0052] The fresh Chuanbei granules containing the composite anti-oxidant protection agent are coarsely crushed with a crusher and set aside;

[0053] (4) Enzymolysis:

[0054] According to the ratio of solid-liquid ratio 1:12, add pure water to the fresh Chuanbei coarse particles obtained in step (2), then add the compound enzyme of 4% of fresh Chuanbei coarse particle weight to carry out enzymolysis, and described compound enzyme is obtained by Cellulase, amylase ...

Embodiment 2

[0062] The processing of embodiment 2 Chuanbei powder

[0063] (1) Cleaning:

[0064] Wash and drain the excavated fresh Chuanbei; chop it;

[0065] (2) Add compound antioxidant protection agent:

[0066] Add 1.2% of its weight to the chopped fresh Chuanbei granule, which is composed of Vc, Vc sodium, Vc phosphate and tea polyphenols; the composite antioxidant protection agent consists of Vc, Vc sodium , Vc phosphate and tea polyphenols are composed in a weight ratio of 4:2:5:3;

[0067] (3) Coarse crushing:

[0068] The fresh Chuanbei granules containing the composite anti-oxidant protection agent are coarsely crushed with a crusher and set aside;

[0069] (4) Enzymolysis:

[0070] Add pure water to the fresh Chuanbei coarse particles obtained in step (2) according to the ratio of material to liquid 1:10, then add the compound enzyme of 10% of the weight of fresh Chuanbei coarse particles to carry out enzymolysis, and the compound enzyme is composed of Cellulase, amylas...

Embodiment 3

[0078] The processing of embodiment 3 Chuanbei powder

[0079] (1) Cleaning:

[0080] Wash and drain the excavated fresh Chuanbei; chop it;

[0081] (2) Add compound antioxidant protection agent:

[0082] Add 1.0% of its weight to the shredded fresh Chuanbei granule, which is composed of Vc, Vc sodium, Vc phosphate and tea polyphenols; the composite antioxidant protection agent consists of Vc, Vc sodium , Vc phosphate and tea polyphenols are composed of 2.5:3:2:2.5 by weight;

[0083] (3) Coarse crushing:

[0084] The fresh Chuanbei granules containing the composite anti-oxidant protection agent are coarsely crushed with a crusher and set aside;

[0085] (4) Enzymolysis:

[0086] According to the ratio of solid-liquid ratio of 1:15, pure water is added to the fresh Chuanbei coarse particles obtained in step (2), and then the compound enzyme of fresh Chuanbei coarse particle weight 8% is added to carry out enzymolysis, and the described compound enzyme is obtained by Cell...

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PUM

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Abstract

The invention discloses a processing method for improving drug effect of tendril-leaved fritillary bulb powder and a product and use, and belongs to the field of medicinal material processing. The processing method for improving the drug effect of the tendril-leaved fritillary bulb powder in preventing and treating of bronchial diseases such as cough and asthma is disclosed based on innovation ofmodern traditional Chinese medicine processing method starting from the theory and practice of the traditional Chinese medicine. The processing method comprises the following steps in turn: taking fresh tendril-leaved fritillary bulb, washing, chopping, adding of Vc, Vc sodium, Vc phosphate and tea polyphenols as protective agents, coarse crushing, enzymatic hydrolysis, ultrafine crushing, low temperature microwave vacuum drying, fine crushing and the like. The method is easy to operate and has a short production cycle. The dissolution of active substances is increased, the loss of active ingredients is reduced, bioavailability is improved, and the tendril-leaved fritillary bulb powder has better drug and treatment effect for the bronchial diseases such as cough and asthma. At the same time, the tendril-leaved fritillary bulb powder is uniform in color, good in smell, and aseptic, and the method has a broad application prospect in the processing area of the tendril-leaved fritillary bulb powder.

Description

technical field [0001] The invention relates to a processing method of Chuanbei, in particular to a processing method capable of improving the efficacy of Chuanbei powder for preventing and treating bronchial diseases such as cough and asthma, and the application of the powder in treating bronchial diseases such as cough and asthma. The invention belongs to the field of medicinal material processing. Background technique [0002] Fritillaria L. is derived from the plant of the genus Fritillaria L. in the family Liliaceae, and is the dried bulb of several species of Fritillaria L. distributed in the western plateau of Sichuan and adjacent areas. Chuanbei is a traditional Chinese medicinal material included in the "Chinese Pharmacopoeia", and its main active ingredients are saponins and alkaloids. Chuan Fritillaria has the effects of relieving cough and relieving asthma, clearing heat and moistening lung, resolving phlegm and relieving cough. [0003] As a precious Chinese h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61K9/14A61K47/22A61K47/46A61P11/14A61P11/06A61P11/00
CPCA61K9/145A61K9/148A61K36/8966A61K2236/15A61K2236/17A61K2236/19
Inventor 于凯何红萍
Owner 四川德仁堂中药科技股份有限公司
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