Application of wogonoside in preparation of anti-rotavirus drug

Abstract

The invention relates to the technical field of wogonoside, in particular to application of the wogonoside in preparation of an anti-rotavirus drug. In the application of the wogonoside in preparationof the anti-rotavirus drug, the applicant firstly finds that the wogonoside has anti-rotavirus effect through study, the blank of the anti-rotavirus drug is filled, and the wogonoside has profound significance and value; and the study shows that molar concentration of the wogonoside in the anti-rotavirus drug is 2.5-160 micromol / L.

Description

technical field [0001] The invention relates to the technical field of wogonoside, in particular to the application of wogonoside in the preparation of anti-rotavirus drugs. Background technique [0002] Rotavirus (RV) is the main pathogen that causes acute diarrhea in infants and young children. About 600,000 infants and young children die each year due to RV infection. It is mainly prevalent in autumn and winter, and its occurrence and prevalence are not affected by sanitary conditions. The incidence rate in developed countries is similar to that in developing countries, but the mortality rate in developing countries is much higher than that in developed countries. RV is generally transmitted through the fecal-oral route, and the incubation period is 2 to 4 days. In the past, it was believed that RV mainly invaded the villi of the small intestinal cells. The main symptom of the patient was diarrhea, with acute onset, more than ten to dozens of times a day, accompanied by ...

AI Technical Summary

Problems solved by technology

[0004] Wogonin (structural formula as follows) is a flavonoid compound derived from the root of Scutellaria baicalensis Georgi, a perennial herb of the genus Scutellaria in the family Labiatae, which has sedative, hepatoprotective, choleretic, antibacterial and anti-inflammatory effects Studies have shown that wogonoside has inhibitory effects on influenza virus, herpes simplex virus, coxsackie virus, respiratory syncytial virus, hepatitis C virus, etc., but whether wogonoside has an effect on RV has not been reported

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