Suppository for treating cold caused by exogenous wind and heat

A technology of exogenous wind-heat and suppositories, which is applied in the direction of suppository delivery, antipyretics, anti-inflammatory agents, etc., can solve the problems of increasing the burden on the liver and kidneys, and achieve the effect of convenient administration

Inactive Publication Date: 2018-08-17
JIANGXI JIUHUA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the drug needs to enter the body and be excreted by the kidneys after being metabolized by the liver. Considering this will increase the burden on the liver and kidneys
[0005] At present, there is no traditional Chinese medicine composition on the market that can clear away heat and detoxify, treat cold and fever caused by exogenous wind-heat, and does not harm the liver and kidney.

Method used

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  • Suppository for treating cold caused by exogenous wind and heat
  • Suppository for treating cold caused by exogenous wind and heat

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Recipe: main drug honeysuckle extract 300g, scutellaria baicalensis extract 375g, forsythia extract 225g

[0036] Excipients: semi-synthetic fatty acid ester (type 36) 450g semi-synthetic fatty acid ester (type 38) 150g

[0037]Preparation method: decoct Scutellaria baicalensis with water three times, the first time for 2 hours, the second and third times for 1 hour each, combine the decoction, filter, and concentrate the filtrate to 1.03 (80°C), add 2mol / L hydrochloric acid solution at 80°C, Adjust the pH value to 1.5, keep it warm for 1 hour, let stand for 24 hours, filter, add 6 times the amount of water to the sediment, adjust the pH value to 7.0 with 40% sodium hydroxide solution, add the same amount of ethanol, stir to dissolve, and filter . The filtrate was adjusted to pH 2.01 with 2mol / L hydrochloric acid solution, kept at 60°C for 30 minutes, allowed to stand for 12 hours, filtered, and the precipitate was washed with water until the pH reached 5.0, followed b...

Embodiment 2

[0039] Recipe: Main drug Honeysuckle extract 225g Scutellaria baicalensis extract 300g Forsythia extract 150g

[0040] Excipients: semi-synthetic fatty acid ester (type 36) 450g semi-synthetic fatty acid ester (type 38) 375g

[0041] Preparation method: Scutellaria baicalensis is decocted with water three times, the first time is 2 hours, the second and third time are 1 hour each, the decoctions are combined, filtered, the filtrate is concentrated to 1.04 (80°C), at 80°C, add 2mol / L hydrochloric acid solution, Adjust the pH value to 1.1, keep it warm for 1 hour, let stand for 24 hours, filter, add 6 times the amount of water to the sediment, adjust the pH value to 7.02 with 40% sodium hydroxide solution, add the same amount of ethanol, stir to dissolve, and filter . The filtrate was adjusted to pH 1.99 with 2mol / L hydrochloric acid solution, kept at 60°C for 30 minutes, allowed to stand for 12 hours, filtered, and the precipitate was washed with water until the pH reached 5.0...

Embodiment 3

[0043] Recipe: main drug honeysuckle extract 225g, scutellaria baicalensis extract 300g, forsythia extract 300g

[0044] Excipients: Semi-synthetic fatty acid ester (type 36) 300g Semi-synthetic fatty acid ester (type 38) 375g

[0045] Preparation method: Scutellaria baicalensis is decocted with water three times, the first time is 2 hours, the second and third time are 1 hour each, the decoctions are combined, filtered, the filtrate is concentrated to 1.08 (80°C), at 80°C, add 2mol / L hydrochloric acid solution, Adjust the pH value to 1.6, keep it warm for 1 hour, let stand for 24 hours, filter, add 7 times the amount of water to the sediment, adjust the pH value to 7.03 with 40% sodium hydroxide solution, add the same amount of ethanol, stir to dissolve, and filter . The filtrate was adjusted to pH 1.98 with 2mol / L hydrochloric acid solution, kept at 60°C for 30 minutes, allowed to stand for 12 hours, filtered, and the precipitate was washed with water until the pH reached 5...

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PUM

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Abstract

The invention discloses a suppository for treating cold caused by exogenous wind and heat. A formula of the suppository comprises the following components: 15%-20% of a honeysuckle extract, 10%-15% ofa fructus forsythiae extract, 20%-25% of a radix scutellariae extract, 20%-30% of 36-type semi-synthetic fatty acid ester, and 10%-35% of 38-type semi-synthetic fatty acid ester. The suppository is an externally applied heat-clearing and detoxifying non-prescription medicine, is used for fever, cough, sore throat, upper respiratory tract infection, pneumonia and the like caused by exogenous windand heat, and can clear away heat and toxic materials, and lightly relieve wind and heat.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a suppository for treating cold caused by exogenous wind-heat. Background technique [0002] Due to the frequent changes in weather, the number of cold patients is increasing day by day, and it takes several weeks for many severe cold patients to recover, which brings great troubles to the patients. Cold is a common and frequently-occurring disease with strong contagious power. It is generally treated or prevented by taking orally or injecting related drugs. Drugs enter the body and need to be excreted by the kidneys after liver metabolism. Considering this will increase the risk of liver and kidney diseases. The burden of liver and kidney will inevitably cause some degree of damage to the liver and kidney, especially for people with liver and kidney insufficiency or liver and kidney disease, it is more important to avoid liver and kidney damage. [0003] Chinese patent (Applica...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/634A61K9/02A61K47/14A61P11/00A61P11/04A61P11/14A61P29/00A61P31/00
CPCA61K36/355A61K9/0031A61K9/02A61K36/539A61K36/634A61K47/14A61K2236/331A61K2236/39A61K2236/53A61P11/00A61P11/04A61P11/14A61P29/00A61P31/00A61K2300/00
Inventor 孙新平雷迅刘中伟
Owner JIANGXI JIUHUA PHARMA
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