Chinese medicine preparation for treating infant rotavirus enteritis and preparation method thereof

A technology for viral enteritis and traditional Chinese medicine preparations, applied in antiviral agents, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as slow effect of controlling symptoms, and achieve less toxic and side effects, simple production process, and easy manufacturing. Effect

Inactive Publication Date: 2011-09-28
南通市星期七旅游开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Although there are many medicines for the treatment of diarrhea in children in traditional Chinese medicine, such as Chinese patent medicines: Pikexin, Jianpi Zhixie San, Changweikang Granules, etc., for those children who have persistent diarrhea, or are accompanied by vomiting and have difficulty taking medicine, they can control symptoms and are effective Slow, it is difficult to solve the problem fundamentally

Method used

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  • Chinese medicine preparation for treating infant rotavirus enteritis and preparation method thereof

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preparation example Construction

[0055] The preparation method of enema of the present invention: take Pulsatilla 1500g, Purslane 1500g, Chinese yam 1500g, Scutellaria baicalensis 1500g, Huoxiang 1500g, Adenophora 1200g, Atractylodes macrocephala 1500g, Poria cocos 1400g, Burnet 1500g, Scallop 1500g, Pueraria 1500g, Coptis 1500g , Chenpi 1600g, Nutmeg 1500g, Pomegranate peel 1500g, Malt 1500g, Polyporus 1500g, Ginger 1500g, Chicken Gold 1500g, add water to extract twice, into extract, it is component 1; In the form of extract, soak dregs in 60-90% ethanol for 0.5-1.5 hours, extract twice, 1-2 hours each time, combine the extracts, filter, concentrate, filter with 80-160 mesh, 6000-10000 rpm The supernatant after centrifugation for 10 minutes is ultrafiltered through an ultrafiltration column with a cut-off molecular weight of 5000-10000, and the ultrafiltrate is concentrated under reduced pressure to a extract with a relative density of 1.35 at 80°C, heated and refluxed for extraction twice, each time for 30 m...

Embodiment 1

[0103] Embodiment 1: Chai, male, 1 year old and 2 months old. Diarrhea for 2 months, more than 5-6 times a day, all dilute water samples, water samples or egg patterns, with a small amount of mucus, no fishy smell; the child is mentally lethargic, dry skin, pale complexion, routine stool examination WBC 0~3 / HP, fat globules ( + ~ + + + ), bacterial cultures were all negative, and stool rotavirus antigens were all positive by ELISA method. Prescription: Pulsatilla 15g, Purslane 10g, Yam 10g, Scutellaria baicalensis 15g , Huoxiang 10g, Adenophora 10g, Atractylodes 10g, Poria 10g, Burnet 10g, Allium 10g, Pueraria 10g, Coptis 15g, Tangerine peel 10g, Nutmeg 15g, Pomegranate peel 10g, Malt 15g, Polyporus 10g, Ginger 15g, Chicken gold 15g, 20mL each time, 3 times a day; decoct the dregs of the medicine as an enema, 1 time a day. One week later, the loose and soft stools were resolved twice a day, and the symptoms improved significantly; after 3 days of consolidation treatment, the ...

Embodiment 2

[0104] Embodiment 2: Jia, man, 9 months. He received treatment in our hospital after 3 days due to cold and diarrhea. More than 5-6 times a day, all are dilute water samples, water samples or egg patterns, with a small amount of mucus, no fishy smell; children are mentally lethargic, dry skin, pale complexion, routine stool examination WBC 0~ 3 / HP , fat globules ( + ~ + + + ), bacterial cultures were all negative, and stool rotavirus antigens were all positive by ELISA. Recipe: Pulsatilla 15g, Purslane 10g, Yam 10g, Scutellaria baicalensis 15g, Huoxiang 10g, Adenophora 10g, Atractylodes macrocephala 10g, Poria cocos 10g, Burnet 10g, Scallop 10g, Pueraria 10g, Coptis 15g, Chenpi 10g, Nutmeg 15g, pomegranate peel 10g, malt 15g, Polyporus 10g, ginger 15g, gallinacea 15g, 20mL each time, 3 times a day; decoct the dregs of the medicine as an enema, once a day. One week later, the loose stools were resolved, and the pills made by the invention were taken for a total of 5 days, an...

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Abstract

The invention discloses a Chinese medicine preparation for treating infant rotavirus enteritis. The Chinese medicine preparation comprises the following raw materials in parts by weight: 10-20 parts of Chinese pulsatilla root, 10-20 parts of purslane, 10-20 parts of yam, 10-20 parts of baical skullcap root, 10-20 parts of wrinkled gianthyssop herb, 10-20 parts of radix glehniae, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of Indian buead, 10-20 parts of burnet, 10-20 parts of longstamen onion bulb, 10-20 parts of kudzu vine root, 10-20 parts of coptis, 10-20 parts of dried tangerine peel, 10-20 parts of nutmeg, 10-20 parts of pomegranate rind, 10-20 parts of malt, 10-20 parts of grifola, 10-20 parts of ginger and 10-20 parts of endothelium corneum gigeriae galli. The preparation has the effects of relieving pain, regulating vital energy, tonifying the spleen, nourishing the spleen, the lung and the kidney, tonifying middle-Jiao and Qi, ascending yang and stopping diarrhea, and is mainly used for treating diarrhea caused by invasion of exogenous evil and weakness of spleen and stomach. The Chinese medicine preparation has the advantages of simple manufacture technology, small toxic side effect, convenience for administration, easiness for manufacture and low cost. The preparation can directly act on the focus, requires short curative time and avoids relapse after rehabilitation.

Description

[0001] technical field [0002] The invention relates to a medical preparation containing raw materials derived from plants, animals or minerals, in particular to a traditional Chinese medicine preparation for treating children with rotavirus enteritis and a preparation method thereof. Background technique [0003] Diarrhea in infants and young children is a common pediatric disease in autumn and winter, most of which are caused by rotavirus. Rotavirus was discovered in duodenal mucosal cell biopsy specimens by Bishop et al. in Melbourne in 1973 when they were studying gastroenteritis in infants and young children. , Rotavirus is one of the main causes of diarrhea in infants and young children. The virus invades the epithelial cells of the small intestine, and the villi shorten and fall off, resulting in the loss of small intestinal function. Mucosa disaccharidase activity decreases, xylose and sucrose in the intestinal cavity are hydrolyzed and absorbed, and are decompose...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P1/12A61P31/14A61K35/37A61K35/57
Inventor 孔建
Owner 南通市星期七旅游开发有限公司
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