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Management of ethanol concentration during syngas fermentation

A technology of ethanol concentration and syngas, applied in fermentation, biofuel, etc., can solve problems such as reactor failure and yield decline

Pending Publication Date: 2018-09-04
巨鹏生物香港公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A certain level of ethanol becomes inhibitory and causes reactor failure or yield loss

Method used

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  • Management of ethanol concentration during syngas fermentation
  • Management of ethanol concentration during syngas fermentation
  • Management of ethanol concentration during syngas fermentation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] Example 1: Water Cycle vs. H 2 and the effect of CO uptake

[0066] Fermentation was carried out with Clostridium ljungdahlii at a STY level of 60 g / L. The ethanol concentration was compared with the total H 2 and a graph of CO uptake are shown in Figure 8 middle. In this fermentation, once the ethanol concentration exceeds 36.8g / L, the water cycle starts immediately. After starting the water cycle, the ethanol concentration dropped to about 28 g / L. h 2 The total uptake of CO and CO reaches a maximum at an ethanol concentration of about 33.7 g / L, and then decreases from about 2.02 mol / min to about 1.85 mol / min when the ethanol concentration exceeds 36 g / L. Once the water cycle started (approximately 537 hours), the ethanol concentration dropped and the total H 2 and CO uptake increased. Continuous fermentation without water recycling results in total H 2 and CO uptake decreased and the culture failed.

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Abstract

The invention relates to management of ethanol concentration during syngas fermentation. A process is provided for management of ethanol concentration during syngas fermentation. A process for fermentation of syngas includes inoculating a medium to provide an inoculated medium. Inoculated medium is contacted with syngas and cells and medium are removed and separated to provide concentrated cells and permeate. Ethanol is separated from the permeate to provide ethanol and a reduced ethanol aqueous stream. The reduced ethanol aqueous stream is returned to the fermentation.

Description

[0001] This application is a divisional application of the international application PCT / US2012 / 068418, which entered the Chinese national phase on June 12, 2014, with the application number 201280061371.X and the title of the invention "Control of ethanol concentration during synthesis gas fermentation". [0002] This application claims the benefit of US Provisional Application No. 61 / 569,355, filed December 12, 2011, which is incorporated by reference in its entirety. technical field [0003] The present invention provides a method of controlling ethanol concentration during synthesis gas fermentation. More specifically, the cells and media are removed from the fermentor and the ethanol-reduced water stream is returned to the fermentor at a rate effective to maintain the desired ethanol concentration. Background technique [0004] Anaerobic microorganisms are capable of producing ethanol from carbon monoxide (CO) by fermentation of gaseous substrates. Ethanol and other us...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12P7/06C12P7/08C12P7/14
CPCC12P7/065C12P7/08C12P7/14Y02E50/10
Inventor 瑞安·塞纳拉特纳刘颂
Owner 巨鹏生物香港公司