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Integrated device based on multiple detection sites and analysis method

A detection cavity and body technology, applied in the field of biochemical analysis, can solve the problems of being unsuitable for use in primary medical institutions, difficult to ensure no human interference, and large sample consumption, so as to realize the detection of whole blood on the machine, eliminate human interference, The effect of small sample usage

Pending Publication Date: 2018-10-12
武汉芯生生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, large hospitals usually use fully automatic biochemical analyzers and specific protein analyzers, both of which contain bulky mechanical sample loading arms with complex structures, expensive prices, large sample consumption, and require professionals to perform reagent calibration, which is not suitable for Primary medical institutions use
[0005] Hospitals below the second level usually use semi-automatic biochemical analyzers and specific protein analyzers, but they require too much manual participation, it is difficult to ensure that they will not be free from human interference, and users are required to complete very professional operations such as reagent calibration, which is troublesome to operate

Method used

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  • Integrated device based on multiple detection sites and analysis method
  • Integrated device based on multiple detection sites and analysis method
  • Integrated device based on multiple detection sites and analysis method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] figure 1 A schematic structural diagram of a biochemical immune analyzer according to an embodiment of the present invention is schematically provided, as figure 1 As shown, the biochemical immune analyzer includes:

[0063] Integrated biochemical device, figure 2 Schematically presents a simplified structural diagram of an integrated biochemical device based on multiple detection sites in an embodiment of the present invention, as shown in figure 2 As shown, the integrated biochemical device includes:

[0064] Body 1, the body has a fixed part 2 suitable for connecting with the rotating shaft of a motor, etc., and is used to rotate under the drive of external power such as a motor; the body is formed with:

[0065] Diluent chamber 3, said diluent chamber 3 is arranged around the outer edge of said fixed part 2; said diluent chamber 3 is preloaded with diluent, and has an outlet 7; in order to prevent leakage when not in use, said The outlet can also be equipped w...

Embodiment 2

[0112] Application example of biochemical immune analyzer and analysis method in biochemical project according to embodiment 1 of the present invention.

[0113] In this application example, if Figure 1-5 As shown, the body is made of resin plastic, which is composed of the first part and the second part arranged up and down. The quantitative chamber, mixing chamber and detection chamber are all formed on the second part through grooves; the diluent and reagents are pre-installed in the integrated In the biochemical device; the first channel adopts a capillary with a bent structure, and the minimum distance from the rotation center of the body to the first channel is smaller than the minimum distance from the rotation center of the body to the first quantitative chamber; the second channel A capillary with a bent structure is adopted, the minimum distance from the rotation center of the body to the second channel is smaller than the minimum distance from the rotation center of ...

Embodiment 3

[0125] An application example of the biochemical immune analyzer and analysis method according to Embodiment 1 of the present invention in immune projects.

[0126] The difference from Embodiment 2 is that the blocking structure adopts a micro-flow valve, and when the rotation speed reaches a certain value, the liquid breaks through the micro-flow valve and enters the next cavity.

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Abstract

The invention provides an integrated device based on multiple detection sites and an analysis method. The integrated device comprises a body; a diluent cavity is formed around the outer edge of a fixed part; a first quantification cavity is formed on the periphery of the diluent cavity; a sample cavity is formed on the periphery of the diluent cavity; a second quantification cavity is formed on the periphery of the sample cavity and is communicated with the sample cavity; a first storage cavity is formed on the periphery of the second quantification cavity, and is communicated with the secondquantification cavity; a second storage cavity is communicated with a second overflow port; a third storage cavity is communicated with a first overflow port; each of first to third passages has a choke flow structure; a mixing cavity is formed on the periphery of the first quantification cavity, and is communication with a distribution cavity by the third passage; the distribution cavity is formed on the periphery of the mixing cavity, and is communicated with a plurality of detection cavities by passages; the plurality of detection cavities are formed on the periphery of the distribution cavity. The integrated device has the advantages of simple structure, complete functions, convenience for operation and the like.

Description

technical field [0001] The invention relates to biochemical analysis, in particular to an integrated device and analysis method based on multiple detection positions. Background technique [0002] Traditional biochemical analyzers use colorimetry and transmission turbidimetry to analyze the substance content of blood samples. Colorimetry can detect most blood biochemical test items, and transmission turbidimetry can detect some blood immune test items. The test method is to add serum samples and reagents into the cuvette to react and detect at 37°C. The reacted liquid will absorb and scatter monochromatic light of different wavelengths, and the transmitted light will become weaker. Get the content of the detected substance. [0003] Traditional specific protein analyzers mostly use the method of scattering turbidimetry for detection. Add samples and reaction reagents to the cuvette to detect the antigen suspended in the liquid and react with the corresponding antibody. Unde...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/53
CPCG01N33/5302
Inventor 陈坦彭绍铁喻婷
Owner 武汉芯生生物科技有限公司
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