Antibacterial patterned surface and method of manufacturing the same

Abstract

The present invention relates to a substrate comprising a plurality of integrally formed surface features, the surface features being micro-sized and / or nano-sized, each surface feature comprising at least one tip. Due to this unique surface, the substrate exhibits biocidal activity, as the ends of the surface features pierce the cell membrane of any microbial cells that come into contact with the substrate, causing cell deformation and lysis. The invention also relates to methods of manufacturing said substrates. Preparation of Cu(OH) by simple treatment of copper or zinc foil with a reagent solution containing base and oxidizing 2 Nanotube arrays, CuO nanoblades and ZnO nanoneedles. These surfaces have been shown to be very effective at killing bacteria (such as E. coli) through physical interaction.

Description

technical field [0001] The present invention generally relates to substrates comprising surface features having antimicrobial properties and methods of making the same. Background technique [0002] About 80% of infectious diseases caused by microorganisms are transmitted by contact, thus posing a serious threat to public health. Therefore, killing microorganisms on frequently touched surfaces is an effective way to avoid cross-infection. [0003] A common method of killing microbes on these surfaces is through chemical means, such as disinfectants. In another approach, antimicrobial surfaces are created to limit cross-infection by grafting or coating the surface with biocidal chemicals or disinfectants. However, microorganisms may evolve and develop resistance to current biocidal chemicals, necessitating the development of new chemicals. Therefore, killing by chemical means will cause secondary pollution. Therefore, these methods face problems such as increased resistan...

AI Technical Summary

Problems solved by technology

In other words, top-down approaches can be time-consuming and expensive and are limited to applications on surfaces of specific materials (e.g., those susceptible to etching or other forms of photolithographic methods)

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